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Relation between Serum Uric Acid Levels and Metabolic Syndrome Markers among Koreans by Gender

한국인의 성별에 따른 혈중 요산 농도와 대사증후군 위험 혈액 지표 간의 관련성

  • Park, Hyunjin (ICAN Nutrition Education and Research) ;
  • Ryu, Hyesook (Dept. of Food and Nutrition, Sangji University) ;
  • Jho, Kwanghyun (Dept. of Business Administration, Sahmyook University) ;
  • Ko, Jaeyoung (National Health Insurance Corporation Ilsan Haspital) ;
  • Yun, Mieun (Dept. of Food and Nutrition, Sahmyook University)
  • 박현진 (ICAN 영양연구소) ;
  • 류혜숙 (상지대학교 식품영양학과) ;
  • 조광현 (삼육대학교 경영학과) ;
  • 고재영 (국민건강보험공단 일산병원영양팀) ;
  • 윤미은 (삼육대학교 식품영양학과)
  • Received : 2016.06.03
  • Accepted : 2016.08.26
  • Published : 2016.10.31

Abstract

It has been reported that the increased uric acid level is associated with metabolic syndrome risk factors in both male and female. However, there has not been enough studies to investigate gender differences of this association in Korea. To evaluate relation between serum uric acids and metabolic syndrome markers, anthropometric and biochemical analyses data was obtained from National Health Examination 2005 and 5,523 (M=3,097; F=2,426) data was analyzed. Results by quartile of serum uric acid levels in females showed that increased serum uric acid level was associated with elevated levels of total-. LDL-cholesterol, and triglycerides, whereas association between serum uric acid and total cholesterol levels was not observed in male subjects. In both female and male, higher quartile of serum uric acid level were linked with lower levels of HDL-cholesterol. In regression analysis, association of serum uric acid levels with fasting glucose levels was significant in female subjects only. In conclusion, higher serum uric acid levels were associated with metabolic syndrome indices, however gender differences were existed for total cholesterol.

Keywords

References

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