Korean Journal of Radiology

The Korean Society of Radiology (대한영상의학회)
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Hemodynamic Measurement Using Four-Dimensional Phase-Contrast MRI: Quantification of Hemodynamic Parameters and Clinical Applications

  • Ha, Hojin (POSTECH Biotech Center, Pohang University of Science and Technology) ;
  • Kim, Guk Bae (Asan Institute of Life Science, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Kweon, Jihoon (Department of Cardiology, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Lee, Sang Joon (POSTECH Biotech Center, Pohang University of Science and Technology) ;
  • Kim, Young-Hak (Department of Cardiology, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Lee, Deok Hee (Department of Radiology, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Yang, Dong Hyun (Department of Radiology, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Kim, Namkug (Department of Radiology, Asan Medical Center, University of Ulsan College of Medicine)
  • Received : 2016.01.20
  • Accepted : 2016.04.22
  • Published : 2016.07.01
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Abstract

Recent improvements have been made to the use of time-resolved, three-dimensional phase-contrast (PC) magnetic resonance imaging (MRI), which is also named four-dimensional (4D) PC-MRI or 4D flow MRI, in the investigation of spatial and temporal variations in hemodynamic features in cardiovascular blood flow. The present article reviews the principle and analytical procedures of 4D PC-MRI. Various fluid dynamic biomarkers for possible clinical usage are also described, including wall shear stress, turbulent kinetic energy, and relative pressure. Lastly, this article provides an overview of the clinical applications of 4D PC-MRI in various cardiovascular regions.

Keywords

Acknowledgement

Supported by : Korea Health Industry Development Institute (KHIDI), National Research Foundation of Korea (NRF)

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