Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
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Anti-fatigue Effect of Kyung-Ok-Ko

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  • Kim, Yong An (College of Pharmacy, Chungnam National University) ;
  • Jin, Sun Woo (College of Pharmacy, Chungnam National University) ;
  • Kim, Soul Mi (College of Pharmacy, Chungnam National University) ;
  • Lee, Gi Ho (College of Pharmacy, Chungnam National University) ;
  • Kim, Se Jong (College of Pharmacy, Chungnam National University) ;
  • Lee, Wang Lok (Department of Sport Science, Chungnam National University) ;
  • Na, MinKyun (College of Pharmacy, Chungnam National University) ;
  • Jeong, Hye Gwang (College of Pharmacy, Chungnam National University)
  • Received : 2016.05.27
  • Accepted : 2016.07.27
  • Published : 2016.09.30
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Abstract

In this study, we tested anti-fatigue effect of Kyung-Ok-Ko (KOK). We examined the exercise performance effects of KOK (600 mg/kg) at 2nd, 3rd and 4th week. The exercise performance of KOK treated group was significantly improved than that of vehicle control (VC) group on grip strength (2nd week), exhausted time of treadmill (3rd week) and exhausted time of weight loaded swimming (4th week). We also investigated the effects of KOK on the change of fatigue parameters in blood, skeletal muscle and liver after swimming exercise. KOK significantly reduced lactate level and enhanced glucose level in blood. Equally KOK significantly increased glycogen in skeletal muscle. However, the glycogen level of KOK in the liver was not significantly increased compared to VC group. These results show that supplementation of KOK may improve the anti-fatigue activity and exercise capacity.

Keywords

References

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