Quantitative Analysis of Taxifolin, (+)-Catechin and Procyanidin B1 from the Preparation of Pinus densiflora (PineXol®)

적송제제(PineXol®)로 부터 Taxifolin과 (+)-Catechin, Procyanidin B1의 함량분석

  • Hwang, Yoon Jeong (Laboratory of Pharmacognosy and Natural Product Derived Medicine, College of Pharmacy, Chung-Ang University) ;
  • Yin, Jun (Laboratory of Pharmacognosy and Natural Product Derived Medicine, College of Pharmacy, Chung-Ang University) ;
  • Le, Thi Tam (Laboratory of Pharmacognosy and Natural Product Derived Medicine, College of Pharmacy, Chung-Ang University) ;
  • Youn, Sung Hye (Laboratory of Pharmacognosy and Natural Product Derived Medicine, College of Pharmacy, Chung-Ang University) ;
  • Ahn, Hye Shin (Laboratory of Pharmacognosy and Natural Product Derived Medicine, College of Pharmacy, Chung-Ang University) ;
  • Kwon, Suk Hyung (Novarex) ;
  • Min, Bok Kee (Novarex) ;
  • Yun, Seong Ho (Novarex) ;
  • An, Yeoung Eun (Novarex) ;
  • Lee, Min Won (Laboratory of Pharmacognosy and Natural Product Derived Medicine, College of Pharmacy, Chung-Ang University)
  • Received : 2016.08.24
  • Accepted : 2016.09.07
  • Published : 2016.09.30

Abstract

Pinus densiflora contained diverse phenol compounds like flavonoid, phenylpropanoid and tannin. PineXol$^{(R)}$ is nutraceutical preparation which was treated from bark of Pinus densiflora. Validation and contents determination of taxifolin, (+)-catechin and procyanidion B1 for the preparation of Pinus densiflora (PineXol$^{(R)}$) were confirmed using High-Performance Liquid Chromatography (HPLC). As a result, content of taxifolin, (+)-catechin and procyanidin B1 were, respectively 4.90%, 2.35% and 8.19%. These analysis method and results could be used as important basic data for the preparation of Pinus densiflora.

Keywords

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