Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
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Chemical Constituents from the Stems of Lagerstroemia indica and Their Anti-oxidant Effect

배롱나무의 항산화 활성 성분

  • Woo, Kyeong Wan (Natural Product Laboratory, School of Pharmacy, Sungkyunkwan University) ;
  • Sim, Mi Ok (Traditional Korean Medicines Research Team, Naional Development Institute of Korea Medicine) ;
  • Park, Eel Jong (Traditional Korean Medicines Research Team, Naional Development Institute of Korea Medicine) ;
  • Kim, Min Suk (Traditional Korean Medicines Research Team, Naional Development Institute of Korea Medicine) ;
  • Suh, Won Se (Natural Product Laboratory, School of Pharmacy, Sungkyunkwan University) ;
  • Cho, Hyun Woo (Traditional Korean Medicines Research Team, Naional Development Institute of Korea Medicine) ;
  • Kwon, Hak Cheol (Natural Product Research Center, Korea Institute of Science and Technology) ;
  • Park, Jong Cheol (Department of Oriental Medicine Resources, Sunchon National University) ;
  • Lee, Kang Ro (Natural Product Laboratory, School of Pharmacy, Sungkyunkwan University)
  • 우경완 (성균관대학교 약학대학 천연물약품화학연구실) ;
  • 심미옥 (한약진흥재단 한약재연구팀) ;
  • 박종일 (한약진흥재단 한약재연구팀) ;
  • 김민석 (한약진흥재단 한약재연구팀) ;
  • 서원세 (성균관대학교 약학대학 천연물약품화학연구실) ;
  • 조현우 (한약진흥재단 한약재연구팀) ;
  • 권학철 (한국과학기술연구원 천연물연구소) ;
  • 박종철 (순천대학교 한약자원개발학과) ;
  • 이강노 (성균관대학교 약학대학 천연물약품화학연구실)
  • Received : 2016.07.11
  • Accepted : 2016.08.30
  • Published : 2016.09.30
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Abstract

Phytochemical investigation of the 80% MeOH extract from the stems of Lagerstroemia indica resulted in the isolation of eighteen compounds; four norsesquiterpenes, fourteen phenolic derivatives. Their chemical structures were characterized by spectroscopic methods to be tachioside (1), isotachioside (2), 2,4,6-trimethoxyphenyl ${\beta}$-D-glucopyranoside (3), gallic acid 4-methyl ether (4), protocatechuic acid (5), gallic acid (6), vanillic acid (7), vanillin (8), 2-methoxy-5-hydroxymethyl-phenyl-1-O-(6"-galloyl)-${\beta}$-D-glucopyranoside (9), 2,4,6-trimethoxyphenol-1-O-${\beta}$-D-(6'-O-galloyl)-glucopyranoside (10), 4-hydroxy-3-methoxyphenyl-1-O-(6'-O-galloyl)-${\beta}$-D-glucopyranoside (11), vomifoliol (12), vomifoliol 9-O-${\beta}$-D-glucopyranoside (13), 6R,9R-3-oxo-${\alpha}$-ionol-9-O-${\beta}$-D-glucopyranoside (14), dihydrophaseic acid 4'-O-${\beta}$-D-glucopyranoside (15), ${\beta}$-hydroxypropiovanillone 3-O-${\beta}$-D-glucopyranoside (16), myrciaphenone A (17), and coumaric acid (18). Compounds 1-5 and 7-18 were isolated for the first time from this plant. Compounds 1-18 were investigated for their antioxidant properties using DPPH and ABTS radical scavenging capacity assay, $Fe^{2+}$ chelating, and FRAP assay. It was found that 4, 6, and 11 possessed the highest antioxidant capacities.

Keywords

References

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