Korean Journal of Radiology

  • 제17권2호
  • /
  • Pages.277-280
  • /
  • 2016
  • /
  • 1229-6929(pISSN)
  • /
  • 2005-8330(eISSN)
대한영상의학회 (The Korean Society of Radiology)
권호 표지
DOI QR코드

DOI QR Code

Chlorfenapyr-Induced Toxic Leukoencephalopathy with Radiologic Reversibility: A Case Report and Literature Review

  • Baek, Byung Hyun (Department of Radiology, Chonnam National University Hospital) ;
  • Kim, Seul Kee (Department of Radiology, Chonnam National University Hwasun Hospital) ;
  • Yoon, Woong (Department of Radiology, Chonnam National University Hospital) ;
  • Heo, Tae Wook (Department of Radiology, Chonnam National University Hospital) ;
  • Lee, Yun Young (Department of Radiology, Chonnam National University Hospital) ;
  • Kang, Heoung Keun (Department of Radiology, Chonnam National University Hwasun Hospital)
  • 투고 : 2015.07.09
  • 심사 : 2015.11.30
  • 발행 : 2016.04.01
⟨ 이전 논문 다음 논문 ⟩

초록

Chlorfenapyr is a widely used, moderately hazardous pesticide. Previous reports have indicated that chlorfenapyr intoxication can be fatal in humans. We reported the first non-fatal case of chlorfenapyr-induced toxic leukoencephalopathy in a 44-year-old female with resolution of extensive and abnormal signal intensities in white matter tracts throughout the brain, brain stem, and spinal cord on serial magnetic resonance imaging.

키워드

참고문헌

  1. United States Environmental Protection Agency. Chlorfenapyr-129093: Health Effects Division Risk Characterization for Use of the Chemical Chlorfenapyr (Alert, EPA File Symbol 5905-GAI) in/on Citrus (6F04623). Web site. http://archive.epa.gov/opprd001/chlorfenapyr/web/pdf/memohed2.pdf. Published February 12, 1998. Accessed June 2, 2015
  2. Kwon JS, Kim HY, Han HJ, Kim JY, Park JH. A case of chlorfenapyr intoxication with central nervous system involvement. J Clinic Toxicol 2012;2:147
  3. Tharaknath VR, Prabhakar YV, Kumar KS, Babu NK. Clinical and radiological findings in chlorfenapyr poisoning. Ann Indian Acad Neurol 2013;16:252-254 https://doi.org/10.4103/0972-2327.112486
  4. Kang C, Kim DH, Kim SC, Kim DS. A patient fatality following the ingestion of a small amount of chlorfenapyr. J Emerg Trauma Shock 2014;7:239-241 https://doi.org/10.4103/0974-2700.136874
  5. United States Environmental Protection Agency. Chlorfenapyr Reason for Issuance: New Chemical Registration. Web site. http://www3.epa.gov/pesticides/chem_search/reg_actions/registration/fs_PC-129093_01-Jan-01.pdf. Accessed June 9, 2015
  6. Choi UT, Kang GH, Jang YS, Ahn HC, Seo JY, Sohn YD. Fatality from acute chlorfenapyr poisoning. Clin Toxicol (Phila) 2010;48:458-459 https://doi.org/10.3109/15563651003750074
  7. Keogh CF, Andrews GT, Spacey SD, Forkheim KE, Graeb DA. Neuroimaging features of heroin inhalation toxicity: "chasing the dragon". AJR Am J Roentgenol 2003;180:847-850 https://doi.org/10.2214/ajr.180.3.1800847
  8. McKinney AM, Kieffer SA, Paylor RT, SantaCruz KS, Kendi A, Lucato L. Acute toxic leukoencephalopathy: potential for reversibility clinically and on MRI with diffusion-weighted and FLAIR imaging. AJR Am J Roentgenol 2009;193:192-206 https://doi.org/10.2214/AJR.08.1176
  9. Sivasubramanian S, Moorthy S, Sreekumar K, Kannan RR. Diffusion-weighted magnetic resonance imaging in acute reversible toxic leukoencephalopathy: a report of two cases. Indian J Radiol Imaging 2010;20:192-194 https://doi.org/10.4103/0971-3026.69354
  10. Ku JE, Joo YS, You JS, Chung SP, Lee HS. A case of survival after chlorfenapyr intoxication with acute pancreatitis. Clin Exp Emerg Med 2015;2:63-66 https://doi.org/10.15441/ceem.15.004

피인용 문헌

  1. Chlorfenapyr Intoxication Manifested by Extensive Leukoencephalomyelopathy vol.36, pp.4, 2018, https://doi.org/10.17340/jkna.2018.4.28
  2. Toxic Optic Neuropathy Caused by Chlorfenapyr Poisoning vol.59, pp.11, 2016, https://doi.org/10.3341/jkos.2018.59.11.1097
  3. Acute chlorfenapyr toxicity in 3 dogs from a single household vol.29, pp.6, 2019, https://doi.org/10.1111/vec.12894
  4. A fatal case of chlorfenapyr poisoning following dermal exposure vol.26, pp.6, 2016, https://doi.org/10.1177/1024907918782065
  5. Magnetic Resonance Imaging and Clinical Features of Chlorfenapyr-Induced Toxic Leukoencephalopathy: A Case Report vol.81, pp.4, 2016, https://doi.org/10.3348/jksr.2020.81.4.985
  6. Spongiform leukoencephalopathy: A unique case of biopsy confirmed leukoencephalopathy secondary to toxic, non-inflammatory exposure vol.9, pp.None, 2016, https://doi.org/10.1177/2050313x211042984