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Review of Korean Clinical Studies on Treatment for Childhood Obesity

소아비만의 치료에 대한 국내 임상연구 동향

  • Kim, Kyoung Ri (Department of Pediatrics, College of Korean Medicine, Daejeon University) ;
  • Han, Jae Kyoung (Department of Pediatrics, College of Korean Medicine, Daejeon University) ;
  • Kim, Yun Hee (Department of Pediatrics, College of Korean Medicine, Daejeon University)
  • 김경리 (대전대학교 한의과대학 소아과학교실) ;
  • 한재경 (대전대학교 한의과대학 소아과학교실) ;
  • 김윤희 (대전대학교 한의과대학 소아과학교실)
  • Received : 2016.07.22
  • Accepted : 2016.08.18
  • Published : 2016.08.31

Abstract

Objectives The purpose of this study is to investigate Korean clinical studies on treatment of childhood obesity and to propose for better treatment options for childhood obesity. Methods Based on RISS, KISS, OASIS, KMbase with the keyword 'childhood obesity', 'child obesity', 'obese child', 'overweight child', total of 21 randomized controlled trials (RCTs), 11 single clinical studies, 3 chart reviews and 3 case reports have been found, and were analyzed. Results and Conclusion 1. Some study subjects were classified based on their sex - only men or women in a group or sometimes both. Another way of classify the study subjects were based on their age - preschooler, primary school students, middle school students, and high school students. The diagnostic criteria of the subjects were BMI (body mass index), Body fat percentage, Obesity index, Weight and unknown criteria. 2. The treatments used in 38 studies were exercise alone, education alone, both exercise and education or herbal therapy. The 7 studies that used herbal therapy as part of their study intervention had a study group with herbal intervention only and the other 2 study group with herbal treatment in addition to exercise and education. 3. 9 studies included herb medicines, electroacupuncture, auricular acupuncture, cupping, aroma massage, infrared light, and abdomen pad. Herb medications used in 5 studies included Chegameuiin-tang 2 kinds, Sobieum, Biman-tnag, and I-razin. 4. The methods of assessment used in 38 studies were classified by 7 categories and anthropometry parameters which is the basic methods are used in all studies 5. Almost studies (29 studies in all 38 studies) were using anthropometric parameters results on significantly effectiveness of childhood obesity. 6. More studies are needed to prove true effectives from various treatments, especially herbal therapy for childhood obesity.

Keywords

References

  1. Hill J, Peters J. Environmental contributions to the obesity epidemic. Sci. 1998;280(5368):1371-4. https://doi.org/10.1126/science.280.5368.1371
  2. Brook C, Lloyd J, Wolf O. Relation between age of onset of obesity and size and number of adipose cells. Br Med J. 1972;2:25-7. https://doi.org/10.1136/bmj.2.5804.25
  3. Jeong IG. Management and exercise for children obesity. JKAK. 2003.
  4. Spear BA, Barlow SE, Ervin C, Ludwig DS, Saelens BE, Schetzina KE, Traveras EM. Recommendations for treatment of child and adolescent overweight and obesity. J Pediatr. 2007;120Suppl4:254-88. https://doi.org/10.1542/peds.2007-2329F
  5. Yang YH. Effects of a 12 week music jump rope exercise program on health-related physical fitness and blood lipid in obese elementary students. Master degree of education in Jeju university. 2015.
  6. Cheon SG. Effects of 12week exercise program arterial function in obese adolescents. Master degree of education in university of Seoul. 2009.
  7. Cho SR, Effects of a high school-based obesity intervention program. Master degree of health education in Hanyang university. 2012.
  8. Bark MJ, Min SJ, Yoo KG, Jun KS, Yeam SR, Kwon YD. A case report of oriental medical treatment for obesity on overweight and obese children of broken home. 2012;22(4):147-56.
  9. Shin JY. Serum levels Leptin and growth hormone in elementary school students in Gwangu area and effects of weight control education program. Master degree of food and nutrition in Chonnam national univiersity. 2005.
  10. Kim JW. The effects regular exercise on metabolic syndrome and insulin resistance in obese middle school boys. Doctor degree of physical education in Kongju national university. 2012.
  11. Han SH. The change of obese child's body compostion, strength, and metabolic syndrome index after physical fitness in a voucher program. Master degree of physical education, Kangwon national university. 2012.
  12. Seo JH. The effects of physical activity on physical composition, physical strength and blood serum RBP4 factors in obese children. Master degree of physical education in Dong-a university. 2010.
  13. Park JH, The effects of combined exercise on endotherial progenitor cell and risk factors of cardiovascular disease in obese children. Master degree of physcial eduation in Dong-a university. 2009.
  14. Park JH, Jeong MK, Kim GM, Park HT, Kim EH, Park SK, Kwon YC. Effects of combined exercise on body composition, physical fitness, and carotid artery structure and function in obese children. Korean Soc Sports Sci. 2013;23(3):1321-9.
  15. Won JS, Jun SH, Han AK. Effects of an obesity control program including rhythmical dance exercise for children with obesity. J Korean Acad Fundam Nurs. 2008;15(4):475-84.
  16. Park JK, Ahn HS, Lee DH, Kim MJ, Lee JH, Lee YJ. Effectiveness of nutrition education program for obese children. Korean J Nutrition. 1994;27(1):90-9.
  17. Lim YK, Min SR, Kim HM, Hur KW, Lee H, Lee JS, Kim HC, Park JW, Park HJ. Comparisons of effects of Biman-tang according to administration period in childhood obesity. J Pediatr Korean Med. 2013;27(4):57-67. https://doi.org/10.7778/jpkm.2013.27.4.057
  18. Ahn JY. The effect of circuit training on obesity-related indicator, brain function-related factor and feeling scale in obese children. Master degree of physical education in Korea university. 2013.
  19. Lee DH, Kim DG. The effects of Sobiem on decrease of body mass index and obesity index of obese children. J Korean Orient Pediatr. 2009;23(1):195-203.
  20. Nam HY, Kang SW, Woo JH. The effects of 24 week training and detraining on cardiac autonomic nervous system activity and antioxidant enzyme gene expression in obese children. J Exerc Nutrition Biochem. 2009;13(4):243-9.
  21. Kang KY, Ahn TW, Han JK. The effects of balneotherapy on obesity index and body composition on obese children. J Pediatr Korean Med. 2013;27(3):29-40. https://doi.org/10.7778/jpkm.2013.27.3.029
  22. Lee HR, Kang YU, Shim JY. Development of an OPD-based childhood obesity control program and the effects of its utilization. J Korean Acad Fam Med. 1998;19(10):787-800.
  23. Bak HG. The effects of child physical activity program on obesity young children's and normal weight young children's body composition, physical fitness, blood lipids and growth-related factors. Master degree of physical education in Pusan national university. 2009.
  24. Yang SY. Effects of track and field exercise program on health-related physical fitness, blood lipid and growth hormone in obese elementary children. Master degree of education in Jeju national university. 2014.
  25. Roh DJ. Prevalence of insulin resistance and metabolic syndrome and effects of health promotion program among obese children in Jeju. Master degree of physical education in Jeju national university. 2012.
  26. Jang JH, Lee SY. Three cases report about obese children over the middle level. J Pediatr Korean Med. 2004;18(2): 179-90.
  27. Jung YS, Ha KS, Kim SY, Lee HY, Choi BM. Outcomes of an community-based intervention program for obese children. APEM. 2006;11(1):85-92.
  28. Lee SW. Effects of Teakwondo training on physical fitness and immune system function in infantile obesity. Master degree of physical education in Dong-a university. 2011.
  29. Yoo JG, Song IB, Lee EJ, Back SR, Koh BH, Lee HY. The effect of education program on weight control in Taeumin childhood obesity. J Korean Orient Med. 2005;26(1):103-14.
  30. Jung BY. The effects of health management program through school homepage on body composition blood lipid profiles and life style patterns of obese adolescent. Master degree of sport science in Kangwon national university. 2008.
  31. Lee YJ. Effects of school-based physical activity program on macro-and microvascular function in obese adolescents. Master degree of physical education in university of Seoul. 2011.
  32. Jeong SH, Lee SY. The evaluation about 10 cases of childhood obesity treatment program in oriental medical center. J Korean Orient Pediatr. 2004;18(2):161-77.
  33. Ju JY, Choi JE, Kim KS. A case study on effect of herbal diet an childhood obese patient. J Korean Med Obes Res. 2003:3(1);69-74.
  34. Kim HJ. The effects of health education and program induced self-participation of exercise on body composition and self-efficiency in obesity and overweight children. Korean J obes. 2007;16(3):130-7.
  35. Cho YJ, Kim EJ, Yang YJ, Song MY. Effects of I-razin in overweight children. J Korean Med Obes Res. 2010;10(2):17-25.
  36. Park JK, Ahn HS, Lee DH. Effects of step by step diet control program in obese children. J Korean Med Obes Res. 2001;10(2):165-73.
  37. Park JK, Ahn HS, Lim KA, Lim IS. The effect of nutrition education in the case of obese children and parents. J Korean Med Obes Res. 1999;8(4).
  38. Cho YG, Song HR, Kim KA, Kang JH, Kang JH, Song YH, Yun HJ, Kim HS. Effect of a school-based intervention for overweight children "Fitness Class" performed on elementary schools located in Seoul. Korean J Obes. 2009;18(4):146-57.
  39. Lee HJ, Yun YS, Kim YH, Kim YM. A study on the effects of obesity management for reducing body fat in children. J Korean Med Obes Res. 1999;8(4).
  40. Ibrahim AK, Michal AY, Gadi R, Shai E, Eran K, Kaeren B, Michal F, Zahi D, Rami R, Matitahu B. Lifestyle modification in an adolescent dormitory: a clinical trial. Korean J Pediatr. 2014;57(23):520-5. https://doi.org/10.3345/kjp.2014.57.12.520
  41. Lee KY, Kim JK, Lee NS, Han JG, Park TJ, Jeon HN. The factors associated with change in percent obesity after obesity treatment among obese children and adolescents. J Korean Acad Fam Med. 2003;24:64-71.
  42. No YH, Lee SY, Kang JH. Short term effects of school-based obesity control programs performed on elementary students. J Korean Acad Fam Med. 2002;23(12):1470-9.
  43. Chu MA, Choe BH. Obesity and metabolic syndrome among children and adolescents in Korea. J Korean Med Assoc. 2010;53(2):142-52. https://doi.org/10.5124/jkma.2010.53.2.142
  44. Park YS, Lee DH, Choi JM, Kang YJ, Kim CH. Trend of obesity in school age children in Seoul over 23 years. Korean J Pediatr. 2004;47:247-57.
  45. Kim HM, Park J, Kim HS, Kim DH. Prevalence of the metabolic syndrome in Korean adolescents aged 12-19 years from the Korean national health and nutrition examination survey 1988 and 2001. Diabetes Res Clin Pract. 2007;75:111-4. https://doi.org/10.1016/j.diabres.2006.04.009
  46. Lim S, Park KS, Lee HK, Cho SI. Changes in the characteristics of metabolic syndrome in Korean over the period 1998-2001 as determined by Korean national health and nutrition examination surveys. Diabetes Care. 2005;28(7):1810-2. https://doi.org/10.2337/diacare.28.7.1810
  47. Barlow SE. Expert committee recommendations regarding the prevention, assessment, and treatment of child and adolescent overweight and obesity: summary report. Pediatr. 2007;120Suppl4:S164-92. https://doi.org/10.1542/peds.2007-2329C
  48. Whitaker RC, Wright JA, Pepe MS, Seidel KD, Dietz WH. Predicting obesity in young adulthood from childhood and parental obesity. N Engl J Med. 1997;337(13):869-93. https://doi.org/10.1056/NEJM199709253371301
  49. Oh SW, Shin SA, Yun YH, Yoo T, Huh BY. Cut-off point of BMI and obesity-related comorbidities and mortality in middle-aged Koreans. Obes Res. 2004;12(12):2031-40. https://doi.org/10.1038/oby.2004.254
  50. Oh SW, Yoon YS, Shin SA. Effect of excess weight on cancer incidences depending on cancer sites and histologic findings among men: Korea national health insurance corporation study. J Clin Oncol. 2005;23(21):4742-54. https://doi.org/10.1200/JCO.2005.11.726
  51. Lee SY. Pharmacotherapy and surgical therapy in the obese children and adolescents. Korean J Fam Med. 2004;25(8):579-84.
  52. Bark BY, Song YK, Lim HH. An analysis of domestic oriental medicine study tendency on obesity-focused on domestic academic journal since 2006. J Korean Med Obes Res. 2010;10(2):1-16.
  53. Ju JW, Nam SU, Lee JD, Choi DY, Ahn BC, Barck DS, Lee YH, Choi YT. Review of effect of electrotherapeutic current to human body. Acupunct. 1996;13(2):335-66.
  54. Huang MH, Yang RC, Hu SH. Preliminary results of triple therapy for obesity. Int J Obes Relat Metab Disord. 1996;20:830-6.
  55. Mazzoni R, Mannucci E, Rizzello SM, Ricca V, Rotella CM. Failure of acupuncture in the treatment of obesity: a pilot study. Eat Weight Disord. 1999;4:198-202. https://doi.org/10.1007/BF03339737
  56. Shafshak TS. Electroacupuncture and exercise in body weight reduction and their application in rehabilitating patients with knee osteoarthritis. Am J Chin Med. 1995;23:15-25. https://doi.org/10.1142/S0192415X95000043
  57. Steiner RP, Kupper N, Davis AW. Obesity and appetite control: comparison of acupuncture therapies and behavior modification. proceedings: international forum on family medicine education. Society of teachers of family medicine. Kansas City, MO. 1983:313-26.
  58. Richards D, Marley J. Stimulation of auricular acupuncture points in weight loss. Aust Fam Physician. 1998;27(2):S73-7.
  59. Millar DB, Hough CJ, Mazorow DL, Gootemberg JE. Beta-endorphin's modulation of lymphocyte proliferation is dose, donor and time dependent. Brain Behav Immun. 1990;4(3):232-42 https://doi.org/10.1016/0889-1591(90)90025-L
  60. Asomoto S, Takeshige C. Activation of the satiety center by auricular acupuncture point stimulation. Brain Res Bull. 1992;29:157-64. https://doi.org/10.1016/0361-9230(92)90021-O
  61. Stux G, Pomeranz B. Acupuncture: textbook and atlas. Berlin: Springer Verlag. 1987.
  62. Dung HC. Role of the vagus nerve in weight reduction through auricular acupuncture. Am J Acupunct. 1986;14:249-54.
  63. The Korean academy of Korean rehabilitation medicine. Korea Rehabil Med. 4th. 2015.
  64. Lee DH, Lee JH. The remedial effect measurement of an obesity remedy machine for home use. Korean Soc Emotion Sensibil. 2005;8(1):37-45.
  65. Pinhas-Hamiel O, Singer S, Pilpel N, Fradkin A, Modan D, Reichman B. Health-related quality of life among children and adolescents: associations with obesity. Int J Obes. 2006;30(2):267-72. https://doi.org/10.1038/sj.ijo.0803107
  66. Deforche BI, Bourdeaudhuij IM, Tanghe AP. Attitude toward physical activity in normal-weight, overweight and obese adolescents. J Adolesc Health. 2006;38(5):560-8. https://doi.org/10.1016/j.jadohealth.2005.01.015

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