The Journal of Pediatrics of Korean Medicine (대한한방소아과학회지)

The Association of Korean Oriental Pediatrics (대한한방소아과학회)
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Review of Clinical Research on Effect of Traditional Chinese Medicine for Febrile Seizure

열성 경련에 대한 중의학 임상 연구 동향 - RCT를 중심으로 -

  • Lee, Bo Ram (Department of Korean Pediatrics, Graduate School, Kyung Hee University) ;
  • Lee, Eun Ju (Department of Korean Pediatrics, Graduate School, Kyung Hee University) ;
  • Lee, Ji Hong (Department of Korean Pediatrics, Graduate School, Kyung Hee University) ;
  • Chang, Gyu Tae (Department of Korean Pediatrics, Graduate School, Kyung Hee University)
  • 이보람 (경희대학교 대학원 소아과학교실) ;
  • 이은주 (경희대학교 대학원 소아과학교실) ;
  • 이지홍 (경희대학교 대학원 소아과학교실) ;
  • 장규태 (경희대학교 대학원 소아과학교실)
  • Received : 2016.07.22
  • Accepted : 2016.08.16
  • Published : 2016.08.31
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Abstract

Objectives The purpose of this study is to provide clinical evidence of Korean medicine for febrile seizure by review of randomized controlled trials on the effect of TCM (traditional Chinese medicine) for febrile seizure. Methods We searched randomized controlled trials about TCM treatment of febrile seizure from the China National Knowledge Infrastructure (CNKI) (January 2008 to June 2016). The selected literatures were assessed by Jadad scale. Results 40 papers were selected from 160 studies. Analyses of selected studies indicated that the TCM treatment group has significantly higher cure rate for febrile seizure than first aid or western medicine group. The most commonly used herbs were Gardeniae Fructus (梔子), Uncariae Ramulus cum Uncis (鉤藤), Cornus Gazeliae (羚羊角), Margarita (珍珠), Scutellariae Radix (黃芩), Glycyrrhizae Radix (甘草). The most commonly used acupoints were GV26 (人中), LI4 (合谷), KI1 (湧泉), GV20 (百會). There were no serious adverse events reported from the TCM treatment group during the treatment period. Conclusions TCM has been shown as not only effective but also safe treatment on febrile seizure. This finding can be widely utilized in clinical practice and can form the basis for development of clinical practice guidelines in future.

Keywords

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