Journal of Sensor Science and Technology (센서학회지)

The Korean Sensors Society (한국센서학회)
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Characteristics of a Bimetal-Layer Chip of a Surface Plasmon Resonance Sensor in the Intensity Interrogation for Tumor Marker Detection

  • Kim, Hyungjin (Dept. of Biomedical Engineering, Catholic University of Daegu) ;
  • Kim, Chang-duk (Dept. of Physics, Kyungpook National Unversity) ;
  • Sohn, Young-Soo (Dept. of Biomedical Engineering, Catholic University of Daegu)
  • Received : 2016.06.13
  • Accepted : 2016.07.28
  • Published : 2016.07.31
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Abstract

The characteristics of a bimetallic surface plasmon resonance (SPR) chip were investigated to detect a tumor biomarker, carcinoembryonic antigen (CEA). The linewidth and the tangential slope of the reflectance curve of the bimetallic SPR chip was compared with those of the reflectance curve of a conventional gold (Au) SPR chip. The changes in reflectance in response to the variation in CEA in the critical concentration range were analyzed at an angle where the tangential slope of the reflectance curve was maximum. From linear regression analysis, the sensitivity of the bimetallic SPR chip with respect to the CEA in critical concentration was obtained.

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References

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