The Journal of the Korea Contents Association (한국콘텐츠학회논문지)

The Korea Contents Association (한국콘텐츠학회)
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Risk Analysis of Factors for Metabolic Diseases according to the Epicaridal Adipose Tissue Thickness - which Focused on the Presented Subjects with Asymptomatic Screening Purposes

심장외막의 지방두께에 따른 대사질환의 위험도 분석 - 무증상의 검진목적으로 내원한 대상자를 위주로

  • 김선화 (화명일신기독병원 영상의학과) ;
  • 김정훈 (부산가톨릭대학교 방사선학과) ;
  • 김창수 (부산가톨릭대학교 방사선학과)
  • Received : 2016.02.29
  • Accepted : 2016.05.10
  • Published : 2016.07.28
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Abstract

Epicardial adipose tissue(EAT) is metabolically active endocrine organ that secretes several hormones in fat thickness is a risk factor for cardiovascular disease and metabolic disorders. This study was to measure and then using ultrasound epicardial adipose tissue thickness, abdominal subcutaneous fat thickness in the target group correlates and general blood properties and characteristics, and presents a local thickness for prediction of metabolic disorders. Results epicardal adipose tissue of the average thickness measured in each of the subjects was 8.890mm, 4.783mm, 4.777, 6.147mm in each section. Showed the epicardial adipose tissue in correlation with the average thickness of the risk factors age, BMI, SBP, LDH, LDL, TC is a positive correlation relationship(p<0.05) in each section. In particular, the thickness of the metabolic disorders epicardial adipose tissue thickness, abdominal subcutaneous compared to subjects that do not have the risk subjects with a risk factor for fat significantly higher(p<0.05). It showed the most reliable that can be cut-off value of 8.950mm obtained with 66.7 % sensitivity and 80 % specificity for predicting the risk of metabolic disorders.

심장외막지방(epicardial adipose tissue, EAT)은 여러 호르몬을 분비하는 대사활성 내분비 기관으로 지방의 두께증가는 심혈관질환이나 대사질환의 위험인자이다. 본 연구는 초음파를 이용하여 대상군의 심장외막 지방두께와 복부피하지방두께를 측정한 후 일반적 특성 및 혈액학적 특성과의 상관관계를 분석하고 대사질환의 예측을 위한 지방두께를 제시하고자 하였다. 연구 결과 대상자의 심장외막지방두께의 평균은 각 단면도에서 각각 8.890mm, 4.783mm, 4.777mm, 6.147mm로 측정되었다. 각 단면에서 심장외막지방두께평균과 위험인자와의 상관관계에서는 나이, BMI, 수축기혈압, LDH, LDL, TC가 양의 상관관계(p<0.05)를 나타냈다. 특히 대사질환의 위험인자를 가지고 있는 대상자가 위험인자를 가지고 있지 않은 대상자에 비하여 심장외막지방두께 및 복부피하지방의 두께가 유의(p<0.05)하게 높게 나타났다. EAT1에서 측정한 심장외막지방 두께 8.950 mm에서 대사질환의 위험을 예측할 수 있는 민감도 66.7 %, 특이도 80 %를 보여 가장 신뢰성 있는 cut off value를 나타냈다.

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