The Journal of Korean Society for Radiation Therapy (대한방사선치료학회지)

Korean Society for Radiation Therapy (대한방사선치료학회)
권호 표지

A dosimetric evaluation of volumetric modulated arc therapy, intensity modulated radiation therapy, and three-dimensional conformal radiation therapy for the lower extremity soft tissue sarcoma

하지 연부조직육종을 위한 방사선치료기술 별 선량평가 연구

  • Lee, SolMin (Department of Radiation Oncology, Jeju National University Hospital, Department of Transdisciplinary Studies, Graduate School of Convergence Science and Technology, Seoul National University, Jeju National University School of Medicine) ;
  • Song, Seongchan (Department of Radiation Oncology, Jeju National University Hospital, Department of Transdisciplinary Studies, Graduate School of Convergence Science and Technology, Seoul National University, Jeju National University School of Medicine) ;
  • Hyun, Sung Eun (Department of Radiation Oncology, Jeju National University Hospital, Department of Transdisciplinary Studies, Graduate School of Convergence Science and Technology, Seoul National University, Jeju National University School of Medicine) ;
  • Park, Heung Deuk (Department of Radiation Oncology, Jeju National University Hospital, Department of Transdisciplinary Studies, Graduate School of Convergence Science and Technology, Seoul National University, Jeju National University School of Medicine) ;
  • Lee, Jaegi (Department of Radiation Oncology, Jeju National University Hospital, Department of Transdisciplinary Studies, Graduate School of Convergence Science and Technology, Seoul National University, Jeju National University School of Medicine) ;
  • Kim, Young Suk (Department of Radiation Oncology, Jeju National University Hospital, Department of Transdisciplinary Studies, Graduate School of Convergence Science and Technology, Seoul National University, Jeju National University School of Medicine) ;
  • Kim, Gwi Eon (Department of Radiation Oncology, Jeju National University Hospital, Department of Transdisciplinary Studies, Graduate School of Convergence Science and Technology, Seoul National University, Jeju National University School of Medicine)
  • 이솔민 (제주대학교병원 방사선종양학과, 서울대학교 융합과학기술대학원 융합과학부, 제주대학교 의학전문대학원) ;
  • 송성찬 (제주대학교병원 방사선종양학과, 서울대학교 융합과학기술대학원 융합과학부, 제주대학교 의학전문대학원) ;
  • 현성은 (제주대학교병원 방사선종양학과, 서울대학교 융합과학기술대학원 융합과학부, 제주대학교 의학전문대학원) ;
  • 박흥득 (제주대학교병원 방사선종양학과, 서울대학교 융합과학기술대학원 융합과학부, 제주대학교 의학전문대학원) ;
  • 이재기 (제주대학교병원 방사선종양학과, 서울대학교 융합과학기술대학원 융합과학부, 제주대학교 의학전문대학원) ;
  • 김영석 (제주대학교병원 방사선종양학과, 서울대학교 융합과학기술대학원 융합과학부, 제주대학교 의학전문대학원) ;
  • 김귀언 (제주대학교병원 방사선종양학과, 서울대학교 융합과학기술대학원 융합과학부, 제주대학교 의학전문대학원)
  • Received : 2016.03.31
  • Accepted : 2016.06.23
  • Published : 2016.06.30
Download PDF
⟨ Previous Next ⟩

Abstract

A dosimetric evaluation of volumetric modulated arc therapy, intensity modulated radiation therapy, and three-dimensional conformal radiation therapy for the lower extremity soft tissue sarcoma For the lower extremity soft tissue sarcoma, volumetric modulated arc therapy, intensity modulated radiation therapy, and three-dimensional conformal radiation therapy were evaluated to compare these three treatment planning technique. The mean doses to the planning target volume and the femur were calculated to evaluate target coverage and the risk of bone fracture during radiation therapy. Volumetric modulated arc therapy can reduce the dose to the femur without compromising target coverage and reduce the treatment time compared with intensity modulated radiation therapy.

본원에서 수술 후 방사선치료를 수행한 하지 연부조직육종 환자에 대해 용적세기조절회전치료(VMAT), 세기조절방사선치료(IMRT), 3차원입체조영방사선치료(3D-CRT)의 세 가지 치료계획을 수립하여 치료계획용적(PTV)과 대퇴골에 전달되는 방사선량을 각각 비교하였다. 세 치료계획방법 모두 치료계획용적에 전달되는 방사선량은 큰 차이를 보이지 않았으나 용적세기조절회전치료와 세기조절방사선치료의 경우 3차원입체조영방사선치료보다 대퇴골에 전달되는 방사선량을 줄일 수 있었다. 또한 용적세기조절회전치료의 경우 세기조절방사선치료 보다 치료에 필요한 monitor unit이 적어 치료시간 감소의 효과가 나타났다. 따라서 하지 연부조직육종 방사선치료 시 용적세기조절회전치료의 사용은 효과적인 방사선치료를 수행할 수 있을 것이라 사료된다.

Keywords

References

  1. Hong L, Alektiar KM, Hunt M, Venkatraman E, Leibel SA: Intensity-modulated radiotherapy for soft tissue sarcoma of the thigh. Int J Radiat Oncol Biol Phys 2004;59:752-759 https://doi.org/10.1016/j.ijrobp.2003.11.037
  2. Stewart AJ, Lee YK, Saran FH: Comparison of conventional radiotherapy and intensity-modulated radiotherapy for post-operative radiotherapy for primary extremity soft tissue sarcoma. Radiother Oncol 2009;93:125-130 https://doi.org/10.1016/j.radonc.2009.06.010
  3. Fogliata A, Scorsetti M, Navarria P, et al.: Dosimetric comparison between VMAT with different dose calculation algorithms and protons for soft-tissue sarcoma radiotherapy. Acta Oncol 2013;52:545-552 https://doi.org/10.3109/0284186X.2012.689853
  4. Dickie CI, Parent AL, Griffin AM, et al.: Bone fractures following external beam radiotherapy and limbpreservation surgery for lower extremity soft tissue sarcoma: relationship to irradiated bone length, volume, tumor location and dose. Int J Radiat Oncol Biol Phys 2009;75:1119-1124 https://doi.org/10.1016/j.ijrobp.2008.12.006
  5. Dickie CI, Parent AL, Chung PW, et al.: Measuring interfractional and intrafractional motion with cone beam computed tomography and an optical localization system for lower extremity soft tissue sarcoma patients treated with preoperative intensitymodulated radiation therapy. Int J Radiat Oncol Biol Phys 2010;78:1437-1444 https://doi.org/10.1016/j.ijrobp.2009.09.054