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Genetic Characterization of an Ancestral Strain of the Avian-Origin H3N2 Canine Influenza Virus Currently Circulating in East Asia

  • Kim, Jeong-Ki (Department of Pharmacy, College of Pharmacy, Korea University) ;
  • Nam, Jeong-Hyun (Department of Pharmacy, College of Pharmacy, Korea University) ;
  • Lyoo, Kwang-Soo (Korea Zoonosis Research Institute, Chonbuk National University) ;
  • Moon, Hyoungjoon (Research Unit, Green Cross Veterinary Products) ;
  • Na, Woonsung (Viral Infectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology) ;
  • Song, Eun-Jung (Department of Pharmacy, College of Pharmacy, Korea University) ;
  • Yeom, Minjoo (Department of Pharmacy, College of Pharmacy, Korea University) ;
  • Shim, Sang-Mu (Department of Pharmacy, College of Pharmacy, Korea University) ;
  • Jeong, Dae Gwin (Viral Infectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology) ;
  • An, Dong-Jun (Animal and Plant Quarantine Agency) ;
  • Kang, Bo-Kyu (Research Unit, Green Cross Veterinary Products) ;
  • Song, Daesub (Department of Pharmacy, College of Pharmacy, Korea University)
  • Received : 2015.11.17
  • Accepted : 2016.03.17
  • Published : 2016.06.28

Abstract

H3N2 canine influenza virus emerged in South Korea in 2007 and subsequently spread to China and Thailand, causing epidemic or endemic respiratory diseases in dogs. Through intermammalian species transmission, the virus has also infected cats. However, no direct evidence of significant genetic evolution has been reported since its first emergence. Here, we describe in depth the genetic and molecular characteristics of the ancestral strain (i.e., the first virus isolate from South Korea) of the H3N2 canine influenza virus currently circulating in East Asia.

Keywords

References

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