한국약용작물학회지 (Korean Journal of Medicinal Crop Science)

  • 제24권3호
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  • Pages.222-227
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  • 2016
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  • 1225-9306(pISSN)
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  • 2288-0186(eISSN)
한국약용작물학회 (The Korean Society of Medicinal Crop Science)
권호 표지
DOI QR코드

DOI QR Code

팔리다자주닭개비 잎 추출물 및 분획물의 항산화 및 α-글루코시다아제 저해 활성

Antioxidant and α-Glucosidase Inhibitory Activities of Tradescantia pallida (Rose) Hunt Leaf Extract and Fractions

  • 김주성 (제주대학교 생명자원과학대학 친환경농업연구소) ;
  • 김경철 (제주대학교 생명자원과학대학 친환경농업연구소)
  • Kim, Ju Sung (Majors in Plant Resource and Environment, College of Agriculture and Life Sciences, SARI, Jeju National University) ;
  • Kim, Kyeoung Cheol (Majors in Plant Resource and Environment, College of Agriculture and Life Sciences, SARI, Jeju National University)
  • 투고 : 2016.04.25
  • 심사 : 2016.06.08
  • 발행 : 2016.06.30
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초록

Background: The biological activities of Tradescantia pallida grown in Korea have not been well determined, thus the aim of this study was to investigate the possibility of using it as a medicinal plant. Methods and Results: To investigate the antioxidant activity, ${\alpha}$-glucosidase inhibitory effect and antimicrobial activity of T. pallida, we performed the 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity and reducing power assay. This assay for T. pallida leaf extract showed the highest antioxidant activity for the ethyl acetate fraction ($RC_{50}=14.55{\pm}0.16{\mu}g/m{\ell}$ and Abs = 0.613 at $300{\mu}g$). Further, the ethyl acetate fraction exhibited higher ${\alpha}$-glucosidase inhibitory effect with an $IC_{50}$ value of $14.1{\pm}0.1{\mu}g/m{\ell}$ and showed antimicrobial activity against gram positive bacteria (minimum inhibitory concentration = $1,000{\mu}g/m{\ell}$). Conclusions: The ethyl acetate fraction of the crude methanol extract of T. pallida showed remarkable antioxidant activity, ${\alpha}$-glucosidase inhibitory effects and antimicrobial activity. These activities might be related to the flavonoid content in the T. pallida leaf extract.

키워드

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피인용 문헌

  1. var. albiflora Nakai. and Cell Viability and DPPH Radical Scavenging Activities of its Extract vol.43, pp.2, 2010, https://doi.org/10.4163/kjn.2010.43.2.105