The Korean Journal of Food And Nutrition (한국식품영양학회지)

The Korean Society of Food and Nutrition (한국식품영양학회)
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Effect of Mulberry Extract on the Lipid Profile and Liver Function in Mice Fed a High Fat Diet

고지방식이와 병행 섭취한 뽕잎가루가 흰쥐의 혈중 지질관계 인자와 간 기능 개선에 미치는 영향

  • 최경순 (삼육대학교 식품영양학과) ;
  • 김용환 (경기대학교 식품생물공학과) ;
  • 신경옥 (삼육대학교 식품영양학과)
  • Received : 2016.04.11
  • Accepted : 2016.06.15
  • Published : 2016.06.30
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Abstract

In this study, we determined the effect of the mulberry leaf powder on blood lipid metabolism and liver function improvement of mice fed a high fat diet. The mulberry leaf showed a moisture content of $10.74{\pm}0.56%$, ash $9.67{\pm}0.56%$, crude protein $25.24{\pm}1.02%$, and crude fat $2.66{\pm}0.08%$. In the group with high fat diet supplemented with mulberry leaf powder, serum low-density lipoprotein (LDL-cholesterol) and total cholesterol levels were significantly lower (p<0.05); also, serum phospholipid and aspartate amino transferase (AST) levels were significantly lower (p<0.05). Serum insulin and leptin levels were high in mice fed a high fat diet; however, addition of mulberry leaf powder 10% in the diet had no significant effect on blood insulin and leptin control. The results of the study suggested that various plant sterols in mulberry leaf improve lipid metabolism and liver function in ICR-mice.

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References

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