Asian Pacific Journal of Cancer Prevention

Asian Pacific Journal of Cancer Prevention (아시아태평양암예방학회)
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Health-Related Quality of Life among Breast Cancer Patients and Influencing Factors in Morocco

  • El Fakir, Samira (Department of Epidemiology and Public Health, Faculty of Medicine, University Sidi Mohammed Ben Abdellah) ;
  • El Rhazi, Karima (Department of Epidemiology and Public Health, Faculty of Medicine, University Sidi Mohammed Ben Abdellah) ;
  • Zidouh, Ahmed (Fondation Lalla Salma Prevention and Treatment of Cancers) ;
  • Bennani, Maria (Fondation Lalla Salma Prevention and Treatment of Cancers) ;
  • Benider, Abdelatif (Oncology Center IbnRochd) ;
  • Errihani, Hassan (National Institute of Oncology) ;
  • Mellass, Nawfel (Department of Oncology, University Hospital Center Hassan II Fez) ;
  • Bekkali, Rachid (Fondation Lalla Salma Prevention and Treatment of Cancers) ;
  • Nejjari, Chakib (Department of Epidemiology and Public Health, Faculty of Medicine, University Sidi Mohammed Ben Abdellah)
  • Published : 2016.12.01
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Abstract

Background: Breast cancer is the most common cancer among women in most countries of the world. It is ranked first in females in Morocco (accounting for 33.4% of the total cancer burden) and more than 60% of cases are diagnosed at stage III or IV. During the last decade, health-related quality of life (HRQOL) has become an important aspect of breast cancer treatment. The objective of this study was to describe self-reported HRQOL in patients with breast cancer and to investigate its associations with sociodemographic and clinical variables. Methods: A prospective study was carried out in the main oncology centers in Morocco. Quality of life was measured using the Moroccan Arabic versions of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire C 30 (EORTC QLQ C30) and the Breast Cancer-Specific Quality of Life Questionnaire (EORTC QLQ-BR23). Statistical analyses were performed using descriptive statistics and multivariate analyses. Results: A total of 1463 subjects were included in the study, with a mean age of 55.6 (SD. 11.2) years, 70% being married. The majority had stage II (45.9%) and a few cases stage IV (12.9%) lesions. The participants' global health mean score was 68.5 and in "functional scales", social functioning scored the highest (Mean 86.2 (SD=22.7)). The most distressing symptom on the symptom scale was financial difficulties (Mean 63.2 (SD=38.2)). Using the disease specific tool, it was found that future perspective scored the lowest (Mean 40.5 (SD=37.3)). On the symptom scale, arm symptoms scored the highest (Mean 23.6 (SD=21.6)). Significant mean differences were noted for many functional and symptom scales. Conclusion: Our results emphasized that the general HRQOL for our study population is lower than for corresponding populations in other countries. This study provided baseline information on the quality of life for a large sample of Moroccan women diagnosed with breast cancer.

Keywords

References

  1. Abu-SaadHuijer H, Abboud S (2012). Health-related quality of life among breast cancer patients in Lebanon. Eur J Oncol Nurs, 16, 491-97.
  2. Ahn SH, Park BW, Noh DY, et al (2007). Health-related quality of life in disease-free survivors of breast cancer with the general population. Ann Oncol,18, 173-82
  3. Alawadi SA, Ohaeri JU (2009). Health - related quality of life of Kuwaiti women with breast cancer: a comparative study using the EORTC quality of life questionnaire. BMC Cancer, 9, 222. https://doi.org/10.1186/1471-2407-9-222
  4. Albert US, Koller M, Wagner U, et al (2004). Survival chances and psychological aspects of quality of life in patients with localized early stage breast cancer. Inflamm Res, 53, 136-41.
  5. Arndt V, Stegmaier C, Ziegler H, et al (2006). A population based study of the impact of specific symptoms on quality of life in women with breast cancer 1 year after diagnosis. Cancer, 107, 2496-503. https://doi.org/10.1002/cncr.22274
  6. Cancer Registry of Greater Casablanca (2012). Registre des cancers du grand Casablanca. 2005-2006-2007.
  7. Coates A, Gebski V, Signorini D, et al (1992). Prognostic value of quality-of-life scores during chemotherapy for advanced breast cancer. Australian New Zealand Breast Cancer Trials Group. J ClinOncol, 10, 1833-38. https://doi.org/10.1200/JCO.1992.10.12.1833
  8. El Fakir S, Abda N, Bendahhou K, et al (2014). The European organization for research and treatment of cancer quality of life questionnaire-BR 23 breast cancer-specific quality of life questionnaire: psychometric properties in a Moroccan sample of breast cancer patients. BMC Res Notes, 7, 53. https://doi.org/10.1186/1756-0500-7-53
  9. Fayers PM, Aaronson NK, Bjordal K, et al (2001). The EORTC QLQ-C30 scoring manual. 3rd ed. Brussels: European organisation for research and treatment of cancer.
  10. Hopwood P, Haviland J, Mills J, et al (2007). START Trial Management Group. The impact of age and clinical factors on quality of life in early breast cancer: an analysis of 2208 women recruited to the UK START Trial (Standardisation of Breast Radiotherapy Trial). Breast, 16, 241-51 https://doi.org/10.1016/j.breast.2006.11.003
  11. Hoyer M, Johansson B, Nordin K, et al (2011). Health-related quality of life among women with breast cancer - a population-based study. ActaOncol, 50, 1015-26.
  12. Ivanauskiene R, Kregzdyte R, Padaiga Z (2010). Evaluation of health-related quality of life in patients with breast cancer. Medicina (Kaunas), 46, 351-9. https://doi.org/10.3390/medicina46050050
  13. Jayasekara H, Rajapaksa LC, Brandberg Y (2008). Measuring breast cancer-specific health-related quality of lifein South Asia: psychometric properties of the Sinhala version of the EORTC QLQ-BR23. Qual Life Res, 17, 927-32. https://doi.org/10.1007/s11136-008-9359-9
  14. King MT (1996). The interpretation of scores from the EORTC quality of life questionnaire QLQ-C30. Qual Life Res, 5, 555-67. https://doi.org/10.1007/BF00439229
  15. Lev EL (1997). Bandura's theory of self-efficacy: applications to oncology. Sch Inq Nurs Pract, 11, 21-35.
  16. Lev EL, Owen SV (2000). Counseling women with breast cancer using principles developed by Albert Bandura. Perspect Psychiatr Care, 36, 131-38.
  17. Lidgren M, Wilking N, Jonsson B, et al (2007). Health related quality of life in different states of breast cancer. Qual Life Res, 16, 1073-81. https://doi.org/10.1007/s11136-007-9202-8
  18. Mandelblatt JS, Eisenburg JM (1995). Historical and methodological perspectives on cancer outcomes research. Oncology, 9, 23-32.
  19. Montazeri A, Gillis CR, McEwen J (1996) Measuring quality of life in oncology: is it worthwhile? Part I. Meaning, purposes, and controversies. Eur J Cancer Care, 5, 159-67.
  20. Montazeri A, Gillis CR, McEwen J (1996). Measuring quality of life in oncology: is it worthwhile? Part II. Experiences from the treatment of cancer. Eur J Cancer Care, 5, 168-75. https://doi.org/10.1111/j.1365-2354.1996.tb00229.x
  21. Montazeri A, Milroy R, Hole D et al (2001). Quality of life in patients with lung cancer: as an important prognostic factor. Lung Cancer, 31, 233-40. https://doi.org/10.1016/S0169-5002(00)00179-3
  22. Montazeri A, Milroy R, Hole D et al (2003). How quality of life data contribute to our understanding of cancer patients' experiences? A study of patients with lung cancer. Qual Life Res, 12, 157-66. https://doi.org/10.1023/A:1022232624891
  23. Ogce F, Ozkan S, Baltalarli B (2007). Psychosocial stressors, social support and socio-demographic variables as determinants of quality of life of Turkish breast cancer patients. Asian Pac J Cancer Prev, 8, 77-82.
  24. Perry S, Kowalski TL, Chang CH (2007). Quality of life assessment in women with breast cancer: benefits, acceptability and utilization. Health Qual Life Outcomes, 5, 24-37. https://doi.org/10.1186/1477-7525-5-24
  25. Sloan FA, Gelband H (2006). Cancer control opportunities in low- and middle-income countries. Washington DC: The National Academies.
  26. Spagnola S, Zabora J, BrintzenhofeSzoc K, et al (2003). The satisfaction with life domains scale for breast cancer (SLDSBC). Breast J, 9, 463-71. https://doi.org/10.1046/j.1524-4741.2003.09603.x
  27. Waldman A, Pritkuleit R, Raspe H, et al (2007). The OVIS study: Health - related quality of life measured by the EORTC QLQC30 and BR23 in German female patients with breast cancer from Schleswig -Holstein. Qual Life Res, 16, 767-76. https://doi.org/10.1007/s11136-006-9161-5