Anthropometric and Reproductive Factors among Newly-Diagnosed Breast Cancer Patients and Healthy Women: A Case-Control Study

  • Zunura'in, Z (Nutrition and Dietetics Program, School of Medical Sciences, Universiti Sains Malaysia) ;
  • Almardhiyah, AR Ainaa (Nutrition and Dietetics Program, School of Medical Sciences, Universiti Sains Malaysia) ;
  • Gan, SH (Human Genome Centre, School of Medical Sciences, Universiti Sains Malaysia) ;
  • Arifin, Wan N (Unit of Biostatistics and Research Methodology, School of Medical Sciences, Universiti Sains Malaysia) ;
  • Sirajudeen, KNS (Department of Chemical Pathology, School of Medical Sciences, Universiti Sains Malaysia) ;
  • Bhavaraju, VMK (Department of Nuclear Medicine, School of Medical Sciences, Universiti Sains Malaysia) ;
  • Shahar, Suzana (Department of Nutrition and Dietetics, Faculty of Allied Health Sciences, Universiti Kebangsaan Malaysia) ;
  • Jan, JM Hamid (Nutrition and Dietetics Program, School of Medical Sciences, Universiti Sains Malaysia)
  • Published : 2016.09.01

Abstract

The objective of this case-control study was to determine anthropometric and reproductive factors associated with the development of breast cancer among women. Fifty-six newly diagnosed breast cancer patients were recruited from the Oncology Clinic, Universiti Sains Malaysia (USM), and 56 healthy female hospital employees were recruited as controls. Socio-demographic and reproductive data were obtained using a standard questionnaire. Anthropometric factors (body weight, height, body fat percentage, visceral fat and waist and hip circumference) were assessed. A high waist circumference (adjusted OR= 1.04, [95% CI: 1.00, 1.09]) and being more than 30 years of age at first full-term pregnancy (adjusted OR=3.77, [95% CI: 1.10, 12.90]) were predictors of breast cancer development. The results of this study indicate that weight and reproductive health management should be emphasized for breast cancer prevention in Malaysia.

Keywords

Acknowledgement

Supported by : Universiti Sains Malaysia RUT

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