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Behavioral and intelligence outcome in 8- to 16-year-old born small for gestational age

  • Yi, Kyung Hee (Department of Pediatrics, Wonkwang University Sanbon Medical Center) ;
  • Yi, Yoon Young (Department of Pediatrics, Hallym University College of Medicine) ;
  • Hwang, Il Tae (Department of Pediatrics, Hallym University College of Medicine)
  • 투고 : 2016.05.11
  • 심사 : 2016.09.07
  • 발행 : 2016.10.15

초록

Purpose: We investigated behavioral problems, attention problems, and cognitive function in children and adolescents born small for gestational age (SGA). Methods: Forty-six SGA children born at term and 46 appropriate for gestational age (AGA) children born at term were compared. Psychiatric symptoms were examined with reference to the Korean-Child Behavior Checklist, Korean-Youth Self Report, and Attention Deficit Hyperactivity Disorder Rating Scale (ADHD-RS). Cognitive function was estimated using the Wechsler Intelligence Scale. Sociodemographic data were recorded from interviews. Results: SGA children had high scores on delinquent behavior, aggressive behavior, and the externalizing scale, and they also showed a propensity for anxiety and depression. The SGA group had a higher mean ADHD-RS score than the AGA group ($10.52{\pm}8.10$ vs.$9.93{\pm}7.23$), but the difference was not significant. The SGA group had a significantly lower verbal intelligence quotient (IQ) than the AGA group, but the mean scores of both groups were within normal limits. Conclusion: This study indicates marked behavioral problems, such as delinquency, aggressiveness, and anxiety and depression, as well as low verbal IQ in the SGA group than in the AGA group. Even in cases in which these symptoms are not severe, early detection and proper treatment can help these children adapt to society.

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참고문헌

  1. Wollmann HA. Intrauterine growth restriction: definition and etiology. Horm Res 1998;49 Suppl 2:1-6.
  2. Paz I, Gale R, Laor A, Danon YL, Stevenson DK, Seidman DS. The cognitive outcome of full-term small for gestational age infants at late adolescence. Obstet Gynecol 1995;85:452-6. https://doi.org/10.1016/0029-7844(94)00430-L
  3. Sommerfelt K, Andersson HW, Sonnander K, Ahlsten G, Ellertsen B, Markestad T, et al. Cognitive development of term small for gestational age children at five years of age. Arch Dis Child 2000; 83:25-30. https://doi.org/10.1136/adc.83.1.25
  4. Viggedal G, Lundalv E, Carlsson G, Kjellmer I. Neuropsychological follow-up into young adulthood of term infants born small for gestational age. Med Sci Monit 2004;10:CR8-16.
  5. Hollo O, Rautava P, Korhonen T, Helenius H, Kero P, Sillanpaa M. Academic achievement of small-for-gestational-age children at age 10 years. Arch Pediatr Adolesc Med 2002;156:179-87. https://doi.org/10.1001/archpedi.156.2.179
  6. O'Keeffe MJ, O'Callaghan M, Williams GM, Najman JM, Bor W. Learning, cognitive, and attentional problems in adolescents born small for gestational age. Pediatrics 2003;112:301-7. https://doi.org/10.1542/peds.112.2.301
  7. Kulseng S, Jennekens-Schinkel A, Naess P, Romundstad P, Indredavik M, Vik T, et al. Very-low-birthweight and term small-for-gestational-age adolescents: attention revisited. Acta Paediatr 2006;95:224-30.
  8. Theodore RF, Thompson JM, Waldie KE, Becroft DM, Robinson E, Wild CJ, et al. Determinants of cognitive ability at 7 years: a longitudinal case-control study of children born small-for-gestational age at term. Eur J Pediatr 2009;168:1217-24. https://doi.org/10.1007/s00431-008-0913-9
  9. Dinesen SJ, Greisen G. Quality of life in young adults with very low birth weight. Arch Dis Child Fetal Neonatal Ed 2001;85:F165-9. https://doi.org/10.1136/fn.85.3.F165
  10. Shin SM, Chang YP, Lee ES, Lee YA, Son DW, Kim MH, et al. Low birth weight, very low birth weight rates and gestational age-specific birth weight distribution of Korean newborn infants. J Korean Med Sci 2005;20:182-7. https://doi.org/10.3346/jkms.2005.20.2.182
  11. Han MH, Yoo AJ. The validation of the child behavior checklist. Korean J Child Stud 1995;16;5-21.
  12. Lee HG, Shin HS, Lee KS. Development of a self-report form of the adolescent problem behavior rating scale: tests of its reliability and validity. Korean J Dev Psychol 2004;17;147-70
  13. Ha EH. A validation study of the Korean Youth Self Report (K- YSR). SM J child study 2005;18:83-104.
  14. Jang SJ, Suh DS, Byun HJ. Normative study of the K-ARS (Korean ADHD Rating Scale) for parents. J Korean Acad Child Adolesc Psychiatry 2007;18:38-48.
  15. Kim YS, So YK, Noh JS, Choi NK, Kim SJ, Koh YJ. Normative data on the Korean ADHD Rating Scales (K-ARS) for parents and teacher. J Korean Neuropsychiatr Assoc 2003;42:352-9.
  16. Kwak KJ, Choi HP, Kim CT. A study for the standardization of K- WISC-III. Korean J Dev Psychol 2002;15;19-33.
  17. Elgen I, Sommerfelt K, Markestad T. Population based, controlled study of behavioural problems and psychiatric disorders in low birthweight children at 11 years of age. Arch Dis Child Fetal Neonatal Ed 2002;87:F128-32. https://doi.org/10.1136/fn.87.2.F128
  18. Botting N, Powls A, Cooke RW, Marlow N. Attention deficit hyperactivity disorders and other psychiatric outcomes in very low birthweight children at 12 years. J Child Psychol Psychiatry 1997; 38:931-41. https://doi.org/10.1111/j.1469-7610.1997.tb01612.x
  19. Hall J, Wolke D. A comparison of prematurity and small for gestational age as risk factors for age 6-13 year emotional problems. Early Hum Dev 2012;88:797-804. https://doi.org/10.1016/j.earlhumdev.2012.05.005
  20. Strauss RS. Adult functional outcome of those born small for gestational age: twenty-six-year follow-up of the 1970 British Birth Cohort. JAMA 2000;283:625-32. https://doi.org/10.1001/jama.283.5.625
  21. Stevenson CJ, Blackburn P, Pharoah PO. Longitudinal study of behaviour disorders in low birthweight infants. Arch Dis Child Fetal Neonatal Ed 1999;81:F5-9. https://doi.org/10.1136/fn.81.1.F5
  22. Rickards AL, Kelly EA, Doyle LW, Callanan C. Cognition, academic progress, behavior and self-concept at 14 years of very low birth weight children. J Dev Behav Pediatr 2001;22:11-8. https://doi.org/10.1097/00004703-200102000-00002
  23. Stjernqvist K, Svenningsen NW. Ten-year follow-up of children born before 29 gestational weeks: health, cognitive development, behaviour and school achievement. Acta Paediatr 1999;88:557-62. https://doi.org/10.1111/j.1651-2227.1999.tb00175.x
  24. Odberg MD, Aukland SM, Rosendahl K, Elgen IB. Cerebral MRI and cognition in nonhandicapped, low birth weight adults. Pediatr Neurol 2010;43:258-62. https://doi.org/10.1016/j.pediatrneurol.2010.05.014
  25. Matte TD, Bresnahan M, Begg MD, Susser E. Influence of variation in birth weight within normal range and within sibships on IQ at age 7 years: cohort study. BMJ 2001;323:310-4. https://doi.org/10.1136/bmj.323.7308.310
  26. Richards M, Hardy R, Kuh D, Wadsworth ME. Birth weight and cognitive function in the British 1946 birth cohort: longitudinal population based study. BMJ 2001;322:199-203. https://doi.org/10.1136/bmj.322.7280.199
  27. Sorensen HT, Sabroe S, Olsen J, Rothman KJ, Gillman MW, Fischer P. Birth weight and cognitive function in young adult life: historical cohort study. BMJ 1997;315:401-3. https://doi.org/10.1136/bmj.315.7105.401
  28. Grantham-McGregor SM. Small for gestational age, term babies, in the first six years of life. Eur J Clin Nutr 1998;52 Suppl 1:S59-64.
  29. Hack M. Effects of intrauterine growth retardation on mental performance and behavior, outcomes during adolescence and adulthood. Eur J Clin Nutr 1998;52 Suppl 1:S65-70. https://doi.org/10.1038/sj.ejcn.1600517
  30. Hack M, Flannery DJ, Schluchter M, Cartar L, Borawski E, Klein N. Outcomes in young adulthood for very-low-birth-weight infants. N Engl J Med 2002;346:149-57. https://doi.org/10.1056/NEJMoa010856
  31. Lagrou K, Vanderfaeillie J, Froidecoeur C, Thomas M, Massa G, Tenoutasse S, et al. Effect of 2 years of high-dose growth hormone therapy on cognitive and psychosocial development in short children born small for gestational age. Eur J Endocrinol 2007;156: 195-201. https://doi.org/10.1530/eje.1.02335
  32. Lohaugen GC, Ostgard HF, Andreassen S, Jacobsen GW, Vik T, Brubakk AM, et al. Small for gestational age and intrauterine growth restriction decreases cognitive function in young adults. J Pediatr 2013;163:447-53. https://doi.org/10.1016/j.jpeds.2013.01.060
  33. Brooks-Gunn J, Klebanov PK, Duncan GJ. Ethnic differences in children's intelligence test scores: role of economic deprivation, home environment, and maternal characteristics. Child Dev 1996; 67:396-408. https://doi.org/10.2307/1131822
  34. Pungello EP, Iruka IU, Dotterer AM, Mills-Koonce R, Reznick JS. The effects of socioeconomic status, race, and parenting on language development in early childhood. Dev Psychol 2009;45:544-57. https://doi.org/10.1037/a0013917
  35. Ment LR, Vohr B, Allan W, Katz KH, Schneider KC, Westerveld M, et al. Change in cognitive function over time in very low-birth-weight infants. JAMA 2003;289:705-11. https://doi.org/10.1001/jama.289.6.705

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