YAKHAK HOEJI (약학회지)

The Pharmaceutical Society of Korea (대한약학회)
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The Change of Ginsenoside Composition in Ginseng Berry Extract by the Ultrasonication Process

초음파 처리 인삼열매 엑스의 인삼사포닌 변화

  • Hong, Jeong Tae (Department of Oriental Medical Food & Nutrition, Semyung University) ;
  • Nam, Yun Min (Department of Oriental Medical Food & Nutrition, Semyung University) ;
  • Kim, Shin Jung (Ginseng Research Center) ;
  • Ko, Sung Kwon (Department of Oriental Medical Food & Nutrition, Semyung University)
  • 홍정태 (세명대학교 한방식품영양학부) ;
  • 남윤민 (세명대학교 한방식품영양학부) ;
  • 김신정 (고연 인삼연구소) ;
  • 고성권 (세명대학교 한방식품영양학부)
  • Received : 2015.12.21
  • Accepted : 2016.03.07
  • Published : 2016.04.30
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Abstract

The purpose of this study is to develop a new preparation process of ginseng berry extracts having high concentrations of ginsenoside Rh1, Rg2, Rg5, F4, a special component of red and black ginseng. Chemical transformation from ginseng saponin glycosides to prosapogenin was analyzed by the HPLC. Extracts of ginseng (Panax ginseng) berry was processed under several treatment conditions including ultrasonication treatments. The content of total saponin reached their heights at 6 hr (UGB-6, 61.760%) of ultrasonication treatment, followed by 10 hr (UGB-10, 53.009%) and 9 hr (UGB-9, 50.652%) of ultrasonication treatment at $100^{\circ}C$. Results of those treatments showed that the quantity of ginsenoside Rh1 increased by over 15% at 10 hr of ultrasonication treatment at $100^{\circ}C$. The results of processing with UGB-10 indicate that the ultrasonication processed ginseng berry extracts that had gone through 10 hr treatments were found to contain the largest amount of ginsenoside Rh1 (15.358%), Rg2 (6.301%), Re (4.567%) and F4 (2.658%). In addition, UGB-6 contained ginsenoside Rg3 (13.632%) at high concentrations. It is thought that such results provide basic information in preparing ginseng berry extracts with functionality enhanced.

Keywords

References

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