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Factors Influencing Allergy related Disease among Korean Adolescents

우리나라 청소년의 알레르기 질환 유병 영향요인

  • 박지혜 (대구보건대학교 치위생학과)
  • Received : 2015.09.16
  • Accepted : 2015.11.23
  • Published : 2016.03.28

Abstract

The purpose of this study was to find out the factors influencing asthma, allergic rhinitis, and atopic dermatitis among Korean adolescents. Data of 72,060 adolescents aged 12 to 18 years were derived from the 10th Korean youth's risk web-based study, which was conducted in 2014. Multiple logistic regression analysis revealed that factors influencing asthma was sex, age, BMI, subjective socioeconomic status, smoking, and subjective perception of stress. Factors influencing allergic rhinitis was age, place of residence, subjective socioeconomic status, drinking, and subjective perception of stress. Factors influencing atopic dermatitis was sex, age, subjective socioeconomic status, drinking, and subjective perception of stress. In conclusion, regulatory policy of lifestyle, such as smoking and drinking adversely affect allergy related disease in adolescents strengthening comprehensive prevention education and stress management are probably the two need to be implemented at national side.

본 연구의 목적은 우리나라 청소년에서 천식, 알레르기 비염 및 아토피 피부염을 포함하는 알레르기 질환의 유병 영향요인을 파악하고자 하는 것이다. 본 연구는 제10차(2014년)청소년건강행태 온라인조사의 원시자료를 이용하였으며, 만 12-18세 청소년 총 72,060명을 연구대상자로 선정하였다. 알레르기 질환 유병 영향요인을 파악하기 위해 로지스틱 회귀분석 결과 모든 변수가 보정된 상태에서 천식은 성별, 연령, 체질량지수, 주관적 경제상태, 흡연 및 주관적 스트레스 인지가 알레르기 비염은 연령, 도시규모, 주관적 경제상태, 음주 및 주관적 스트레스 인지가 아토피 피부염은 성별, 연령, 주관적 경제상태, 음주 및 주관적 스트레스 인지가 알레르기 질환 유병 영향요인으로 나타났다. 따라서 앞으로 청소년의 알레르기 질환에 악영향을 미치는 흡연과 음주와 같은 생활습관들의 규제정책 강화, 포괄적인 예방교육 및 스트레스 관리가 국가적 측면에서 시행될 필요가 있다.

Keywords

References

  1. T. Ozdoganoglu and M. Songu, "The burden of allergic rhinitis and asthma," Therapeutic advances in respiratory disease, Vol.6, No.1, pp.11-23, 2012. https://doi.org/10.1177/1753465811431975
  2. E. O. Meltzer, M. S. Blaiss, M. J. Derebery, T. A. Mahr, B. R. Gordon, K. K. Sheth, A. L. Simmons, M. A. Wingertzahn, and J. M. Boyle, "Burden of allergic rhinitis: results from the pediatric allergies in America survey," The J. of allergy and clinical immunology, Vol.124, No.3 Suppl, pp.S43-S70, 2009. https://doi.org/10.1016/j.jaci.2009.05.013
  3. R. A. Nathan, "The burden of allergic rhinitis," Allergy and asthma proceedings, Vol.28, No.1, pp.3-9, 2007. https://doi.org/10.2500/aap.2007.28.2934
  4. M. I. Asher, U. Keil, H. R. Anderson, R. Beasley, J. Crane, F. Martinez, E. A. Mitchell, N. Pearce, B. Sibbald, A. W. Stewart, D. Strachan, S. K. Weiland, and H. C. Williams, International study of asthma and allergies in childhood (ISAAC): rationale and methods," The European respiratory j., Vol.8, No.3, pp.483-491, 1995. https://doi.org/10.1183/09031936.95.08030483
  5. 안강모, 김지현, 권호장, 채유미, 함명일, 이기재, 박용민, 이소연, 한만용, 김우경, "2010년 한국 어린이 . 청소년의 천식, 알레르기 비결막염, 아토피 피부염 증상 유병률 조사: 복합표본설계를 이용한 전국 서베이," 대한의사협회지, 제54권, 제7호, pp.769-778, 2011. https://doi.org/10.5124/jkma.2011.54.7.769
  6. M. I. Asher, S. Montefort, B. Bjorksten, C. K. Lai, D. P. Strachan, S. K. Weiland, and H. Williams, "Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry cross-sectional surveys," Lancet, Vol.368, No.9537, pp.733-743, 2006. https://doi.org/10.1016/S0140-6736(06)69283-0
  7. N. Ghouri, J. Hippisley-Cox, J. Newton, and A. Sheikh, "Trends in the epidemiology and prescribing of medication for allergic rhinitis in England," J. of the royal society of medicine, Vol.101, No.9, pp.466-472, 2008. https://doi.org/10.1258/jrsm.2008.080096
  8. R. Mosges and L. Klimek, "Today's allergic rhinitis patients are different: new factors that may play a role," Allergy, Vol.62, No.9, pp.969-975, 2007. https://doi.org/10.1111/j.1398-9995.2007.01440.x
  9. World Heath Organization, WHO report on the global tobacco epidemic, 2013, Geneva: World Heath Organization, 2013.
  10. http://www.nosmokeguide.or.kr/mbs/nosmokeguide/subview.jsp?id=nosmokeguide_010402000000
  11. Centers for disease control and prevention, A report of the surgeon general: preventing tobacco use among youth and young adults, Centers for disease control and prevention, 2012.
  12. K. J. Lee, "Current smoking and secondhand smoke exposure and depression among Korean adolescents: analysis of a national cross-sectional survey," BMJ Open, Vol.4, No.2, p.e003734, 2014. https://doi.org/10.1136/bmjopen-2013-003734
  13. 질병관리본부, 제10차(2014년) 청소년건강행태 온라인조사 통계, 질병관리본부, 2014.
  14. http://www.oecd.org/health/health-data.htm
  15. M. Ezzati, A. D. Lopez, A. Rodgers, S. Vander Hoorn, and C. J. Murray, "Selected major risk factors and global and regional burden of disease," Lancet, Vol.360, No.9343, pp.1347-1360, 2002. https://doi.org/10.1016/S0140-6736(02)11403-6
  16. http://www.hidoc.co.kr/news/healthtoday/item/C0000001056
  17. E. Cakir, R. Ersu, Z. S. Uyan, S. Oktem, N. Varol, F. Karakoc, B. Karadag, M. Akyol, and E. Dagli, "The prevalence and risk factors of asthma and allergic diseases among working adolescents," Asian Pacific j. of allergy and immunology, Vol.29, No.2-3, pp.122-129, 2010.
  18. C. H. Lee, H. Y. Chuang, C. H. Hong, S. K. Huang, Y. C. Chang, Y. C. Ko, and H. S. Yu, "Lifetime exposure to cigarette smoking and the development of adult-onset atopic dermatitis," The British j. of dermatology, Vol.164, No.3, pp.483-489, 2011. https://doi.org/10.1111/j.1365-2133.2010.10116.x
  19. P. Bendtsen, M. Gronbaek, S. K. Kjaer, C. Munk, A. Linneberg, and J. S. Tolstrup, "Alcohol consumption and the risk of self-reported perennial and seasonal allergic rhinitis in young adult women in a population-based cohort study," Clinical and experimental allergy, Vol.38, No.7, pp.1179-1185, 2008. https://doi.org/10.1111/j.1365-2222.2008.02945.x
  20. T. M. McKeever, S. A. Lewis, C. Smith, J. Collins, H. Heatlie, M. Frischer, and R. Hubbard, "Siblings, multiple births, and the incidence of allergic disease: a birth cohort study using the West Midlands general practice research database," Thorax, Vol.56, No.10, pp.758-762, 2001. https://doi.org/10.1136/thorax.56.10.758
  21. 성경미, 청소년의 아토피 피부염 관련 요인 분석(국민건강영양조사 3기를 대상으로), 연세대학교 보건대학원, 석사학위논문, 2010.
  22. 이경석, 한국 소아청소년 알레르기질환의 역학과 위험인자 분석, 경희대학교 의학대학원, 박사학위논문, 2012.
  23. 김효주, 한미아, 김소희, 박선미, 박종, 류소연, 최성우, "우리나라 남녀 청소년에서 흡연, 음주와 아토피 피부염 평생 진단 경험과의 관련성," 한국모자보건학회, 제18권, 제2호, pp.175-185, 2014.
  24. 조정민, "환경성 질환인 아토피 피부염을 가진 청소년의 건강행위 분석," 한국생활환경학회, 제20권, 제1호, pp.57-63, 2013.
  25. 질병관리본부, 2007 소아.청소년 표준 성장도표, 질병관리본부, 2007.
  26. http://www.korl.or.kr/information/nose-disease-04.html
  27. 윤인숙, 권세영, "알레르기 환자에서 Immunoglobulin E와 Eosinophil count 및 Allergen과의 관련성," 한국콘텐츠학회논문지, 제9권, 제4호, pp.236-246, 2009. https://doi.org/10.5392/JKCA.2009.9.4.236
  28. S. I. Lee, J. Kim, Y. Han, and K. Ahn, "A proposal: Atopic Dermatitis Organizer (ADO) guideline for children," Asia Pacific allergy, Vol.1, No.2, pp.53-63, 2011. https://doi.org/10.5415/apallergy.2011.1.2.53
  29. N. Novak and T. Bieber, "Allergic and nonallergic forms of atopic diseases," The J. of allergy and clinical immunology, Vol.112, No.2, pp.252-262, 2003. https://doi.org/10.1067/mai.2003.1595
  30. F. Vazquez Nava, A. H. Saldivar Gonzalez, G. Martinez Perales, D. Lin Ochoa, M. C. Barrientos Gomez, E. M. Vazquez Rodriguez, C. F. Vazquez Rodriguez, and F. J. Beltran Guzman, "Associations between family history of allergy, exposure to tobacco smoke, active smoking, obesity, and asthma in adolescents," Archivos de bronconeumologia, Vol.42, No.12, pp.621-626, 2006. https://doi.org/10.1016/S1579-2129(07)60003-2
  31. 구희조, 이상민, 이상표, 한은아, "인천지역 청소년에서 천식, 알레르기성 비염, 아토피피부염과 체질량지수와의 관계," Allergy asthma & respiratory disease, 제2권, 제4호, pp.243-250, 2014. https://doi.org/10.4168/aard.2014.2.4.243
  32. 정혜미, 황민영, 신초영, 김솔리, 윤철호, 서운교, "비만과 알레르기 비염의 상관성에 관한 연구," 동의생리병리학회지, 제24권, 제6호, pp.1099-1104, 2010년.
  33. A. E. Dixon, F. Holguin, A. Sood, C. M. Salome, R. E. Pratley, D. A. Beuther, J. C. Celedon, and S. A. Shore, "An official American Thoracic Society Workshop report: obesity and asthma," Proceedings of the American thoracic society, Vol.7, No.5, pp.325-335, 2010. https://doi.org/10.1513/pats.200903-013ST
  34. 유정경, 신재영, 유정섭, 정수인, 송준섭, 양승, 황일태, 이하백, 백혜성, "천식 소아에서 혈청 렙틴과 만니톨 기관지 과민성과의 관계," 대한천식알레르기학회, 제2권, 제1호, pp.30-37, 2014.
  35. F. Forastiere, N. Agabiti, G. M. Corbo, V. Dell'Orco, D. Porta, R. Pistelli, S. Levenstein, and C. A. Perucci, "Socioeconomic status, number of siblings, and respiratory infections in early life as determinants of atopy in children," Epidemiology, Vol.8, No.5, pp.266-570, 1997.
  36. D. P. Strachan, L. S. Harkins, I. D. Johnston, and H. R. Anderson, "Childhood antecedents of allergic sensitization in young British adults," The J. of allergy and clinical immunology, Vol.99, No.1, pp.6-12, 1997. https://doi.org/10.1016/S0091-6749(97)81038-X
  37. C. Almqvist, G. Pershagen, and M. Wickman, "Low socioeconomic status as a risk factor for asthma, rhinitis and sensitization at 4 years in a birth cohort," Clinical and experimental allergy, Vol.35, No.5, pp.612-618, 2005. https://doi.org/10.1111/j.1365-2222.2005.02243.x
  38. I. Gudelj, I. Mrkic Kobal, H. Munivrana Skvorc, K. Mise, Z. Vrbica, D. Plavec, and N. Tudoric "Intraregional differences in asthma prevalence and risk factors for asthma among adolescents in Split-Dalmatia County, Croatia," Medical science monitor, Vol.18, No.4, pp.PH43-PH50, 2012. https://doi.org/10.12659/MSM.882609
  39. J. Saulyte, C. Regueira, A. Montes-Martinez, P. Khudyakov, and B. Takkouche, "Active or passive exposure to tobacco smoking and allergic rhinitis, allergic dermatitis, and food allergy in adults and children: a systematic review and meta-analysis," Public library of science medicine, Vol.11, No.3, p.e1001611, 2014.
  40. A. Gonzalez-Quintela, F. Gude, O. Boquete, J. Rey, L. M. Meijide, F. Suarez, M. C. Fernandez-Merino, L. F. Perez, and C. Vidal, "Association of alcohol consumption with total serum immunoglobulin E levels and allergic sensitization in an adult population-based survey," Clinical and experimental allergy, Vol.33, No.2, pp.199-205, 2003. https://doi.org/10.1046/j.1365-2222.2003.01582.x
  41. H. Vally and P. J. Thompson, "Allergic and asthmatic reactions to alcoholic drinks," Addiction biology, Vol.8, No.1, pp.3-11, 2003. https://doi.org/10.1080/1355621031000069828
  42. Y. Chida, M. Hamer, and A. Steptoe, "A bidirectional relationship between psychosocial factors and atopic disorders: a systematic review and meta-analysis," Psychosomatic medicine, Vol.70, No.1, pp.102-116, 2008. https://doi.org/10.1097/PSY.0b013e31815c1b71
  43. R. J. Wright, R. T. Cohen, and S. Cohen, "The impact of stress on the development and expression of atopy," Current opinion in allergy and clinical immunology, Vol.5, No.1, p.29, 2005.
  44. G. D Marshall and S. R. Roy, Psychoneuroimmunology: Stress and allergic diseases, Academic Press, 2007.
  45. B. S. McEwen, "Protective and damaging effects of stress mediators," The New England j. of medicine, Vol.338, No.3, pp.171-179, 1998. https://doi.org/10.1056/NEJM199801153380307
  46. U. Matterne, J. Schmitt, T. L. Diepgen, and C. Apfelbacher, "Children and adolescents' health-related quality of life in relation to eczema, asthma and hay fever: results from a population-based cross-sectional study," Quality of life research, Vol.20, No.8, pp.1295-1305, 2011. https://doi.org/10.1007/s11136-011-9868-9
  47. Y. Lu, K. K. Mak, H. P. van Bever, T. P. Ng, A. Mak, and R. C. Ho, "Prevalence of anxiety and depressive symptoms in adolescents with asthma: a meta-analysis and meta-regression," Pediatric allergy and immunology, Vol.23, No.8, pp.707-715, 2012. https://doi.org/10.1111/pai.12000
  48. E. L. McQuaid, S. J. Kopel, and J. H. .Nassau, "Behavioral adjustment in children with asthma: a meta-analysis," J. of developmental and behavioral pediatrics, Vol.22, No.6, pp.430-439, 2001. https://doi.org/10.1097/00004703-200112000-00011
  49. C. Rutishauser, S. M. Sawyer, and G. Bowes, "Quality-of-life assessment in children and adolescents with asthma," The European respiratory j., Vol.12, No.2, pp.486-494, 1998. https://doi.org/10.1183/09031936.98.12020486
  50. W. Cui, M. M. Zack, and H. S. Zahran, "Health-related quality of life and asthma among United States adolescents," The J. of pediatrics, Vol.166, No.2, pp.358-364, 2015. https://doi.org/10.1016/j.jpeds.2014.10.005
  51. http://www.cdc.go.kr/CDC/contents/CdcKrContentView.jsp?cid=21837&menuIds=HOME001-MNU1130-MNU0754-MNU1094