DOI QR코드

DOI QR Code

Surgery versus Nerve Blocks for Lumbar Disc Herniation : Quantitative Analysis of Radiological Factors as a Predictor for Successful Outcomes

  • Kim, Joohyun (Department of Neurosurgery, College of Medicine, Korea University, Anam Hospital) ;
  • Hur, Junseok W. (Department of Neurosurgery, College of Medicine, Korea University, Anam Hospital) ;
  • Lee, Jang-Bo (Department of Neurosurgery, College of Medicine, Korea University, Anam Hospital) ;
  • Park, Jung Yul (Department of Neurosurgery, College of Medicine, Korea University, Anam Hospital)
  • Received : 2016.06.11
  • Accepted : 2016.08.16
  • Published : 2016.09.01

Abstract

Objective : To assess the clinical and radiological factors as predictors for successful outcomes in lumbar disc herniation (LDH) treatment. Methods : Two groups of patients with single level LDH (L4-5) requiring treatment were retrospectively studied. The surgery group (SG) included 34 patients, and 30 patients who initially refused the surgery were included in the nerve blocks group (NG). A visual analogue scale (VAS) for leg and back pain and motor deficit were initially evaluated before procedures, and repeated at 1, 6, and 12 months. Radiological factors including the disc herniation length, disc herniation area, canal length-occupying ratio, and canal area-occupying ratio were measured and compared. Predicting factors of successful outcomes were determined with multivariate logistic regression analysis after the optimal cut off values were established with a receiver operating characteristic curve. Results : There was no significant demographic difference between two groups. A multivariate logistic regression analysis with radiological and clinical (12 months follow-up) data revealed that the high disc herniation length with cutoff value 6.31 mm [odds ratio (OR) 2.35; confidence interval (CI) 1.21-3.98] was a predictor of successful outcomes of leg pain relief in the SG. The low disc herniation length with cutoff value 6.23 mm (OR 0.05; CI 0.003-0.89) and high baseline VAS leg (OR 12.63; CI 1.64-97.45) were identified as predictors of successful outcomes of leg pain relief in the NG. Conclusion : The patients with the disc herniation length larger than 6.31 mm showed successful outcomes with surgery whereas the patients with the disc herniation length less than 6.23 mm showed successful outcomes with nerve block. These results could be considered as a radiological criteria in choosing optimal treatment options for LDH.

Keywords

References

  1. Asch HL, Lewis PJ, Moreland DB, Egnatchik JG, Yu YJ, Clabeaux DE, et al. : Prospective multiple outcomes study of outpatient lumbar microdiscectomy : should 75 to 80% success rates be the norm? J Neurosurg 96 (1 Suppl) : 34-44, 2002
  2. Aydin Y, Ziyal IM, Duman H, Turkmen CS, Basak M, Sahin Y : Clinical and radiological results of lumbar microdiskectomy technique with preserving of ligamentum flavum comparing to the standard microdiskectomy technique. Surg Neurol 57 : 5-13; discussion 13-14, 2002 https://doi.org/10.1016/S0090-3019(01)00677-2
  3. Beynon R, Hawkins J, Laing R, Higgins N, Whiting P, Jameson C, et al. : The diagnostic utility and cost-effectiveness of selective nerve root blocks in patients considered for lumbar decompression surgery : a systematic review and economic model. Health Technol Assess 17 : 1-88, v-vi, 2013
  4. Carlisle E, Luna M, Tsou PM, Wang JC : Percent spinal canal compromise on MRI utilized for predicting the need for surgical treatment in single-level lumbar intervertebral disc herniation. Spine J 5 : 608-614, 2005 https://doi.org/10.1016/j.spinee.2005.05.384
  5. Carragee EJ, Han MY, Suen PW, Kim D : Clinical outcomes after lumbar discectomy for sciatica : the effects of fragment type and anular competence. J Bone Joint Surg Am 85-A : 102-108, 2003
  6. Carragee EJ, Kim DH : A prospective analysis of magnetic resonance imaging findings in patients with sciatica and lumbar disc herniation. Correlation of outcomes with disc fragment and canal morphology. Spine (Phila Pa 1976) 22 : 1650-1660, 1997 https://doi.org/10.1097/00007632-199707150-00025
  7. Cheng J, Wang H, Zheng W, Li C, Wang J, Zhang Z, et al. : Reoperation after lumbar disc surgery in two hundred and seven patients. Int Orthop 37 : 1511-1517, 2013 https://doi.org/10.1007/s00264-013-1925-2
  8. Compston A : Aids to the investigation of peripheral nerve injuries. Medical Research Council : Nerve Injuries Research Committee. His Majesty's Stationery Office : 1942; pp. 48 (iii) and 74 figures and 7 diagrams; with aids to the examination of the peripheral nervous system. By Michael O'brien for the Guarantors of Brain. Saunders Elsevier : 2010; pp. [8] 64 and 94 figures. Brain 133 : 2838-2844, 2010 https://doi.org/10.1093/brain/awq270
  9. Cowan NC, Bush K, Katz DE, Gishen P : The natural history of sciatica : a prospective radiological study. Clin Radiol 46 : 7-12, 1992 https://doi.org/10.1016/S0009-9260(05)80025-X
  10. Datta S, Manchikanti L, Falco FJ, Calodney AK, Atluri S, Benyamin RM, et al. : Diagnostic utility of selective nerve root blocks in the diagnosis of lumbosacral radicular pain : systematic review and update of current evidence. Pain Physician 16 (2 Suppl) : SE97-SE124, 2013
  11. Greiner M, Pfeiffer D, Smith R : Principles and practical application of the receiver-operating characteristic analysis for diagnostic tests. Prev Vet Med 45 : 23-41, 2000 https://doi.org/10.1016/S0167-5877(00)00115-X
  12. Grzybowski M, Younger JG : Statistical methodology : III. Receiver operating characteristic (ROC) curves. Acad Emerg Med 4 : 818-826, 1997 https://doi.org/10.1111/j.1553-2712.1997.tb03793.x
  13. Herron LD : Selective nerve root block in patient selection for lumbar surgery : surgical results. J Spinal Disord 2 : 75-79, 1989
  14. Jacobs WC, van Tulder M, Arts M, Rubinstein SM, van Middelkoop M, Ostelo R, et al. : Surgery versus conservative management of sciatica due to a lumbar herniated disc : a systematic review. Eur Spine J 20 : 513-522, 2011 https://doi.org/10.1007/s00586-010-1603-7
  15. Kanna RM, Shetty AP, Rajasekaran S : Patterns of lumbar disc degeneration are different in degenerative disc disease and disc prolapse magnetic resonance imaging analysis of 224 patients. Spine J 14 : 300-307, 2014 https://doi.org/10.1016/j.spinee.2013.10.042
  16. Knop-Jergas BM, Zucherman JF, Hsu KY, DeLong B : Anatomic position of a herniated nucleus pulposus predicts the outcome of lumbar discectomy. J Spinal Disord 9 : 246-250, 1996
  17. Lurie JD, Tosteson TD, Tosteson AN, Zhao W, Morgan TS, Abdu WA, et al. : Surgical versus nonoperative treatment for lumbar disc herniation : eight-year results for the spine patient outcomes research trial. Spine (Phila Pa 1976) 39 : 3-16, 2014 https://doi.org/10.1097/BRS.0000000000000088
  18. Macnab I : Negative disc exploration. An analysis of the causes of nerveroot involvement in sixty-eight patients. J Bone Joint Surg Am 53 : 891-903, 1971 https://doi.org/10.2106/00004623-197153050-00004
  19. Matsubara Y, Kato F, Mimatsu K, Kajino G, Nakamura S, Nitta H : Serial changes on MRI in lumbar disc herniations treated conservatively. Neuroradiology 37 : 378-383, 1995 https://doi.org/10.1007/BF00588017
  20. Narozny M, Zanetti M, Boos N : Therapeutic efficacy of selective nerve root blocks in the treatment of lumbar radicular leg pain. Swiss Med Wkly 131 : 75-80, 2001
  21. Overdevest GM, Vleggeert-Lankamp CL, Jacobs WC, Brand R, Koes BW, Peul WC, et al. : Recovery of motor deficit accompanying sciatica--subgroup analysis of a randomized controlled trial. Spine J 14 : 1817-1824, 2014 https://doi.org/10.1016/j.spinee.2013.07.456
  22. Riew KD, Park JB, Cho YS, Gilula L, Patel A, Lenke LG, et al. : Nerve root blocks in the treatment of lumbar radicular pain. A minimum fiveyear follow-up. J Bone Joint Surg Am 88 : 1722-1725, 2006 https://doi.org/10.2106/JBJS.E.00278
  23. Riew KD, Yin Y, Gilula L, Bridwell KH, Lenke LG, Lauryssen C, et al. : The effect of nerve-root injections on the need for operative treatment of lumbar radicular pain. A prospective, randomized, controlled, doubleblind study. J Bone Joint Surg Am 82-A : 1589-1593, 2000
  24. Saal JA, Saal JS : Nonoperative treatment of herniated lumbar intervertebral disc with radiculopathy. An outcome study. Spine (Phila Pa 1976) 14 : 431-437, 1989 https://doi.org/10.1097/00007632-198904000-00018
  25. Sin AH, Caldito G, Smith D, Rashidi M, Willis B, Nanda A : Predictive factors for dural tear and cerebrospinal fluid leakage in patients undergoing lumbar surgery. J Neurosurg Spine 5 : 224-227, 2006 https://doi.org/10.3171/spi.2006.5.3.224
  26. Solberg T, Johnsen LG, Nygaard OP, Grotle M : Can we define success criteria for lumbar disc surgery? : estimates for a substantial amount of improvement in core outcome measures. Acta Orthop 84 : 196-201, 2013 https://doi.org/10.3109/17453674.2013.786634
  27. Swets JA : Measuring the accuracy of diagnostic systems. Science 240 : 1285-1293, 1988 https://doi.org/10.1126/science.3287615
  28. Weber H : Lumbar disc herniation. A controlled, prospective study with ten years of observation. Spine (Phila Pa 1976) 8 : 131-140, 1983 https://doi.org/10.1097/00007632-198303000-00003
  29. Weiner BK, Fraser RD : Foraminal injection for lateral lumbar disc herniation. J Bone Joint Surg Br 79 : 804-807, 1997 https://doi.org/10.1302/0301-620X.79B5.7636
  30. Wittenberg RH, Lutke A, Longwitz D, Greskotter KH, Willburger RE, Schmidt K, et al. : The correlation between magnetic resonance imaging and the operative and clinical findings after lumbar microdiscectomy. Int Orthop 22 : 241-244, 1998 https://doi.org/10.1007/s002640050250

Cited by

  1. Lumbar Disc Herniation vol.10, pp.4, 2016, https://doi.org/10.1007/s12178-017-9441-4
  2. Predictors of Successful Outcomes of Selective Nerve Root Blocks for Acute Lumbar Disc Herniation vol.9, pp.5, 2016, https://doi.org/10.1177/2192568218800050