Journal of the korean academy of Pediatric Dentistry (대한소아치과학회지)

Korean Academy of Pediatric Dentistry (대한소아치과학회)
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Prevalence of Periodontopathogens in Saliva and Plaque of Korean Children and Adolescents

한국 소아·청소년의 타액과 치태 내 치주 병원균 출현율

  • Choi, Hyejin (Department of Pediatric Dentistry and Institute of Oral Bioscience, School of Dentistry, Chonbuk National University) ;
  • Kim, Jaehwan (Department of Pediatric Dentistry and Institute of Oral Bioscience, School of Dentistry, Chonbuk National University) ;
  • Lee, Daewoo (Department of Pediatric Dentistry and Institute of Oral Bioscience, School of Dentistry, Chonbuk National University) ;
  • Yang, Yeonmi (Department of Pediatric Dentistry and Institute of Oral Bioscience, School of Dentistry, Chonbuk National University) ;
  • Kim, Jaegon (Department of Pediatric Dentistry and Institute of Oral Bioscience, School of Dentistry, Chonbuk National University)
  • 최혜진 (전북대학교 치의학전문대학원 소아치과학교실 및 구강생체과학연구소) ;
  • 김재환 (전북대학교 치의학전문대학원 소아치과학교실 및 구강생체과학연구소) ;
  • 이대우 (전북대학교 치의학전문대학원 소아치과학교실 및 구강생체과학연구소) ;
  • 양연미 (전북대학교 치의학전문대학원 소아치과학교실 및 구강생체과학연구소) ;
  • 김재곤 (전북대학교 치의학전문대학원 소아치과학교실 및 구강생체과학연구소)
  • Received : 2015.05.27
  • Accepted : 2015.07.29
  • Published : 2016.02.29
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Abstract

Early colonization of periodontal pathogens has been related as a risk indicator for the subsequent development of periodontal disease. Such colonization can be easily detected with mediums like saliva and plaque. This study aimed to evaluate the prevalence of the bacteria associated with periodontal disease in saliva and plaque in healthy children and adolescents. The experiment was conducted using 90 samples from subjects consisting of thirty elementary school students, thirty high school students and thirty adults. PCR was used to detect the prevalence and distribution of five periodontal pathogens in the collected saliva and plaque. The detected periodontal pathogens are as follows: A. actinomycetemcomitans, P. gingivalis, T. forsythia, F. nucleatum and P. intermedia. Periodontal pathogens were prevailed in a higher number of adolescents than the number of children. A. actinomycetemcomitans and P. intermedia were detected the most in the adolescents group. T. forsythia and F. nucleatum were detected the most in the children group. The overall result showed that saliva is more a useful medium than supragingival plaque. The detection of high risk periodontal pathogens in children and adolescents without clinical signs of periodontal disease can emphasize the importance of the early diagnosis and preventive approach.

소아에서 치주 병원균의 조기 집락은 향후 치주 질환으로 발전될 위험 인자로 작용할 수 있으므로 원인균의 조기 진단과 예방이 최선의 치료라 할 수 있다. 이 연구는 치주적으로 건강한 어린이와 청소년에서 타액과 치태를 채취하고, PCR을 사용하여 주요 치주 질환 원인균 5종의 분포 정도를 조사하였으며, 나아가 타액과 치태의 검출 차이를 비교 분석하였다. A. actinomycetemcomitans와 P. intermedia는 고등학생(만17세)에서, T. forsythia와 F. nucleatum는 초등학생(만8세)에서 가장 많이 검출되었다. 반면, P. gingivalis는 모든 대상에서 발견되지 않았다. 그리고 치은연상치태보다 타액에서 유의하게 검출이 더 잘 된 것으로 나타났다. 치주 병원균이 상대적으로 더 많이 검출된 청소년기에서는 치주 질환 예방을 위한 구강위생교육이 더욱 강화될 필요가 있으며, 치주 질환의 조기진단 및 관련 연구에 있어서 타액은 보다 유용한 도구가 될 것이라 사료된다.

Keywords

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