한국의료질향상학회지 (Quality Improvement in Health Care)

  • 제22권2호
  • /
  • Pages.15-25
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  • 2016
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  • 1225-7613(pISSN)
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  • 2288-078X(eISSN)
한국의료질향상학회 (Korean Society for Quality in Health Care)
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Detection and characterization of Clostridium difficile infections tracking the trends of Clostridium difficile culture

  • Ock, Min-Su (Department of Preventive Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Oh, Jin-Sun (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Kim, Hwa-Jung (Department of Clinical Epidemiology and Biostatistics, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Lyu, Yong-Man (Office of Clinical Research Information, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Lee, Moo-Song (Department of Preventive Medicine, Asan Medical Center, University of Ulsan College of Medicine)
  • 투고 : 2016.11.02
  • 심사 : 2016.12.21
  • 발행 : 2016.12.31
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초록

Objectives: In this study, we examined the validity of Clostridium difficile culture results as a proxy measure of Clostridium difficile infection, and inferred the epidemiologic characteristics of Clostridium difficile infection by tracking the trends of Clostridium difficile culture results. Methods: We reviewed the medical records to figure out the actual possibilities of Clostridium difficile infection of those with positive or negative results of Clostridium difficile culture during the time span from January 2012 to March 2012. We calculated the positive and negative predictive value of Clostridium difficile culture results for Clostridium difficile infection. Furthermore, epidemiologic characteristics of Clostridium difficile infection in a tertiary general hospital in 2012 were analyzed. Result: The estimated positive predictive value of Clostridium difficile culture tests for Clostridium difficile infection was 100%, and the estimated negative predictive value was around 94.4~99.3% depending on the cutoff value of possibility of Clostridium difficile infection. A total of 622 cases were identified as Clostridium difficile infection in a tertiary general hospital in 2012 and there were 4.9 patients with Clostridium difficile infection per 1,000 inpatients. Conclusion: In conclusion, we identified that Clostridium difficile culture results can be used as a proxy measure of Clostridium difficile infection.

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참고문헌

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