Journal of Integrative Natural Science (통합자연과학논문집)

The Basic Science Institute Chosun University (조선대학교 기초과학연구원)
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Protein Absorption and Characterization of Hydrogel Polymer Containing 2-Methacryloyloxyethyl Phosphorylcholine as Additive

  • Kim, Duck-Hyun (Department of Optometry & Vision Science, Catholic University of Daegu) ;
  • Sung, A-Young (Department of Optometry & Vision Science, Catholic University of Daegu)
  • Received : 2016.08.25
  • Accepted : 2016.12.25
  • Published : 2016.12.31
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Abstract

This study evaluated the physical and optical characteristics of hydrophilic ophthalmic polymer with addition of 2-methacryloyloxyethyl phosphorylcholine in the basic hydrogel ophthalmic lens material, and in particular, the utility of 2-methacryloyloxyethyl phosphorylcholine as an ophthalmic contact lens material for ophthalmologic devices was investigated. In this study 2-methacryloyloxyethyl phosphorylcholine were used as additives. For the preparation of hydrogel lens 2-hydroxyethyl methacrylate, methyl methacrylate, acrylic acid and a cross-linker EGDMA were copolymerized in the presence of AIBN as an initiator. The physical properties of the produced polymers were measured as followings. The refractive index of 1.433~1.393, water content of 35.95~53.16%, contact angle of $70.6{\sim}51.24^{\circ}$, UVB transmittance of 81.2~82.4%, UV-B transmittance of 81.2~82.4% and visible transmittance of 91.4~92.2% were obtained. Also, in case of protein absorption, the measurement showed that absorbance of Reference and MPC-10 sample was 0.2598 and 0.2250 respectively. Based on the results of this study, ophthalmic lens material containing 2-methacryloyloxyethyl phosphorylcholine is expected to be used usefully as a material for high wettability and inhibitor of protein adsorption for ophthalmic hydrogel lens.

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References

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