한국자기공명학회논문지 (Journal of the Korean Magnetic Resonance Society)

한국자기공명학회 (Korean Magnetic Resonance Society)
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Backbone Assignment of the N-terminal Domain of Human Replication Protein A 70 kDa

  • Lee, Sungjin (Department of Chemistry, Gwangju Institute of Science and Technology) ;
  • Park, Chin-Ju (Department of Chemistry, Gwangju Institute of Science and Technology)
  • 투고 : 2016.10.16
  • 심사 : 2016.12.07
  • 발행 : 2016.12.20
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초록

Replication Protein A (RPA) is the eukaryotic single-stranded DNA binding protein. It involves in DNA replication, repair, and damage response. Among three subunits, RPA70 has a protein-protein binding domain (RPA70N) at the N-terminal. It has known that the domain recruits several damage response proteins to the damaged site. Also, it is suggested that there are more candidates that interact with RPA70N. Even though several studies performed on the structural aspects of RPA70N and its ligand binding, the backbone assignments of RPA70N is not available in public. In this study, we present the backbone assignments of RPA70N.

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참고문헌

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