대한소아치과학회지 (Journal of the korean academy of Pediatric Dentistry)

  • 제43권4호
  • /
  • Pages.435-442
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  • 2016
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  • 1226-8496(pISSN)
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  • 2288-3819(eISSN)
대한소아치과학회 (Korean Academy of Pediatric Dentistry)
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아산화질소 농도 및 적용방법에 따른 생리학적 변화

Determination of Physiological Changes according to Nitrous Concentration and Application Method

  • 이대우 (전북대학교 치의학전문대학원 소아치과학교실 및 구강생체과학연구소) ;
  • 한지훈 (전북대학교 치의학전문대학원 소아치과학교실 및 구강생체과학연구소) ;
  • 양연미 (전북대학교 치의학전문대학원 소아치과학교실 및 구강생체과학연구소)
  • Lee, Daewoo (Department of Pediatric Dentistry and Institute of Oral Bioscience, School of Dentistry, Chonbuk National University) ;
  • Han, Jihoon (Department of Pediatric Dentistry and Institute of Oral Bioscience, School of Dentistry, Chonbuk National University) ;
  • Yang, Yeonmi (Department of Pediatric Dentistry and Institute of Oral Bioscience, School of Dentistry, Chonbuk National University)
  • 투고 : 2016.10.20
  • 심사 : 2016.10.27
  • 발행 : 2016.11.30
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초록

본 연구는 $N_2O/O_2$ 흡입진정을 시행하였을 때, 농도 및 투여방법에 따른 환자의 생징후 변화, 주관적인 증상 및 부작용에 대해 알아보고자 하였다. 본 연구는 흡입진정법에 대한 금기증이 없는 19 - 35세 성인 남녀 65명을 대상으로 실험조사를 진행하였다. 흡입진정법은 $N_2O$의 농도를 약 1분 간격으로 10%씩 높여주는 방법으로 적정하거나, 한 번에 $N_2O$의 농도를 원하는 수준으로 올려주는 방법을 시행하였다. 각각의 방법으로 30% 또는 50% $N_2O$ 농도에 도달되도록 하였다. 산소포화도는 $N_2O$ 농도와 투여방법에 따라서 유의성 있는 결과를 보이지 않았다. 맥박수는 한 번에 $N_2O$를 고농도로 투여하는 경우 진정법 중과 100% $O_2$ 5분 투여 후 유의성 있는 감소를 보였다. 따라서 $N_2O$ 농도는 서서히 올려주는 것이 환자 맥박수의 감소량을 줄이는 것이 안전하다.

The aim of this study was to analyze physiological changes, clinical and subjective symptoms by different $N_2O$ concentrations and administration method. This study surveyed 65 men and women ages 19 to 35 and all subjects were healthy volunteers, with no contraindication for use of $N_2O$ sedation. The $N_2O$ sedation was carried out in a way that increases by 10 percent to one-minute interval or increases at once the desired level. Each method was required to reach 30 or 50 percent $N_2O$ concentration. The way to gradually raise the $N_2O$ concentration can reduce the risk by decreasing the pulse reduction rate at the same $N_2O$ concentration. $SpO_2$ has no statistical significance according to $N_2O$ concentration and method of administration. Pulse rate reduced significantly when 50% $N_2O$ increase at once during sedation and 100% $O_2$ after 5 minutes. The way to gradually raise the $N_2O$ concentration is safe for reducing pulse rate.

키워드

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