Journal of Microbiology and Biotechnology

The Korean Society for Microbiology and Biotechnology (한국미생물·생명공학회)
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First Description of Shigella sonnei Harboring blaCTX-M-55 Outside Asia

  • Zurita, Jeannete (Facultad de Medicina, Pontificia Universidad Catolica del Ecuador) ;
  • Ortega-Paredes, David (Unidad de Investigaciones en Biomedicina, Zurita & Zurita Laboratorios) ;
  • Barba, Pedro (Unidad de Investigaciones en Biomedicina, Zurita & Zurita Laboratorios)
  • Received : 2016.05.23
  • Accepted : 2016.08.17
  • Published : 2016.12.28
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Abstract

Shigella sonnei harboring $bla_{CTX-M-55}$ was isolated outside of Asia for the first time. The $bla_{CTX-M-55}$ gene was found to be downstream of ISEcp-1 and located in a ~130 kb conjugative plasmid belonging to the I1 incompatibility group. The strain was recovered from a 7-year-old Ecuadorian girl with watery diarrhea who had not travelled abroad. Recent local data describe the emergence of $bla_{CTX-M-55}$ and other variants typically found in Asia in the Andean Region, suggesting that increased travel of humans and trade relationships with Asian countries are influencing the current Ecuadorian bacterial resistance situation.

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References

  1. Anderson M, Sansonetti PJ, Marteyn BS. 2016. Shigella diversity and changing landscape: insights for the twentyfirst century. Front. Cell. Infect. Microbiol. 6: 45.
  2. Bartoloni A, Sennati S, Di Maggio T, Mantella A, Riccobono E, Strohmeyer M, et al. 2016. Antimicrobial susceptibility and emerging resistance determinants (blaCTX-M, rmtB, fosA3) in clinical isolates from urinary tract infections in the Bolivian Chaco. Int. J. Infect. Dis. 43: 1-6. https://doi.org/10.1016/j.ijid.2015.12.008
  3. Carattoli A, Bertini A, Villa L, Falbo V, Hopkins KL, Threlfall EJ. 2005. Identification of plasmids by PCR-based replicon typing. J. Microbiol. Methods 63: 219-228. https://doi.org/10.1016/j.mimet.2005.03.018
  4. Delgado DY, Barrigas ZP, Astutillo SG, Jaramillo AP, Ausili A. 2016. Detection and molecular characterization of ${\beta}$-lactamase genes in clinical isolates of Gram-negative bacteria in Southern Ecuador. Braz. J. Infect. Dis. DOI: 10.1016/ j.bjid.2016.07.001.
  5. Ellis RE. 2007. El impacto de China en Ecuador y América Latina. Available from http://asiapacifico.utadeo.edu.co/wpcontent/files/impacto_china_ecuador.pdf.
  6. González-Torralba A, García-Esteban C, Alós JI. 2015. Enteropathogens and antibiotics. Enferm. Infecc. Microbiol. Clin. DOI: 10.1016/j.eimc.2015.06.015.
  7. Guzmán-Blanco M, Labarca JA, Villegas MV, Gotuzzo E; Latin America Working Group on Bacterial Resistance. 2014. Extended spectrum ${\beta}$-lactamase producers among nosocomial Enterobacteriaceae in Latin America. Braz. J. Infect. Dis. 18: 421-433. https://doi.org/10.1016/j.bjid.2013.10.005
  8. He D, Partridge SR, Shen J, Zeng Z, Liu L, Rao L, et al. 2013. CTX-M-123, a novel hybrid of the CTX-M-1 and CTX-M-9 group ${\beta}$-lactamases recovered from Escherichia coli isolates in China. Antimicrob. Agents Chemother. 57: 4068-4071. https://doi.org/10.1128/AAC.00541-13
  9. Hu YY, Cai JC, Zhou HW, Chi D, Zhang XF, Chen WL, et al. 2013. Molecular typing of CTX-M-producing Escherichia coli isolates from environmental water, swine feces, specimens from healthy humans, and human patients. Appl. Environ. Microbiol. 79: 5988-5996. https://doi.org/10.1128/AEM.01740-13
  10. Kantele A, Lääveri T, Mero S, Vilkman K, Pakkanen SH, Ollgren J, et al. 2016. Antimicrobials increase travelers' risk of colonization by extended-spectrum ${\beta}$-lactamase-producing Enterobacteriaceae. Clin. Infect. Dis. 60: 837-846.
  11. Lee W, Chung HS, Lee H, Yum JH, Yong D, Jeong SH, et al. 2013. CTX-M-55-type extended-spectrum ${\beta}$-lactamase-producing Shigella sonnei isolated from a Korean patient who had travelled to China. Ann. Lab. Med. 33: 141-144. https://doi.org/10.3343/alm.2013.33.2.141
  12. Ministerio de Salud Pública. 2016. Gaceta Epidemiológica Ecuador SIVE-ALERTA. Available from http://www.salud.gob.ec/ gaceta-epidemiologica-ecuador-sive-alerta.
  13. Ortega-Paredes D, Barba P, Zurita J. 2016. Colistin-resistant Escherichia coli clinical isolate harbouring the mcr-1 gene in Ecuador. Epidemiol. Infect. 144: 2967-2970. https://doi.org/10.1017/S0950268816001369
  14. Qu F, Ying Z, Zhang C, Chen Z, Chen S, Cui E, et al. 2014. Plasmid-encoding extended-spectrum ${\beta}$-lactamase CTX-M55 in a clinical Shigella sonnei strain, China. Future Microbiol. 9: 1143-1150. https://doi.org/10.2217/fmb.14.53
  15. Radice M, González C, Power P, Vidal MC, Gutkind G. 2001. Third-generation cephalosporin resistance in Shigella sonnei, Argentina. Emerg. Infect. Dis. 7: 442-443. https://doi.org/10.3201/eid0703.017313
  16. Rashid H, Rahman M. 2015. Possible transfer of plasmid mediated third generation cephalosporin resistance between Escherichia coli and Shigella sonnei in the human gut. Infect. Genet. Evol. 30: 15-18. https://doi.org/10.1016/j.meegid.2014.11.023
  17. Valverde A, Turrientes MC, Norman F, San Martín E, Moreno L, Pérez-Molina JA, et al. 2015. CTX-M-15-nonST131 Escherichia coli isolates are mainly responsible of faecal carriage with ESBL-producing Enterobacteriaceae in travellers, immigrants and those visiting friends and relatives. Clin. Microbiol. Infect. 21: e1-e4. https://doi.org/10.1016/j.cmi.2014.08.006
  18. Zhang J, Zheng B, Zhao L, Wei Z, Ji J, Li L, et al. 2014. Nationwide high prevalence of CTX-M and an increase of CTX-M-55 in Escherichia coli isolated from patients with community-onset infections in Chinese county hospitals. BMC Infect. Dis. 14: 659. https://doi.org/10.1186/s12879-014-0659-0
  19. Zhao WH, Hu ZQ. 2013. Epidemiology and genetics of CTX-M extended-spectrum ${\beta}$-lactamases in gram-negative bacteria. Crit. Rev. Microbiol. 39: 79-101. https://doi.org/10.3109/1040841X.2012.691460

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