한국방사선학회논문지 (Journal of the Korean Society of Radiology)

  • 제10권8호
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  • Pages.611-618
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  • 2016
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  • 1976-0620(pISSN)
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  • 2384-0633(eISSN)
한국방사선학회 (The Korean Society of Radiology)
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양성질환의 방사선치료

Radiotherapy for Benign Diseases

  • 최상규 (단국대병원 방사선종양학과)
  • Choi, Sang Gyu (Department of Radiation Oncology, Dankook University College of Medicine)
  • 투고 : 2016.11.23
  • 심사 : 2016.12.31
  • 발행 : 2016.12.31
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초록

암의 3대 표준요법중의 하나인 방사선치료는 전통적으로 악성 종양인 암의 근치적 혹은 고식적 치료외에도 일부 증식성이거나 염증성을 보이는 양성 질환에서도 그동안 꾸준하게 시행되어왔다. 양성질환의 경우 악성 종양과는 달리 약물요법이나 보존요법 또는 수술로 만족할 만한 치료성적을 낼 수 있으나 이런 치료들이 실패하거나 불가능한 경우 저선량의 방사선치료를 추가하거나 병용하여 시행하는 경우 인체에 큰 문제없이 안전하고 용이하게 통증완화나 재발율을 의미있게 낮출 수 있다. 최근 방사선치료기법의 발달로 정상조직을 최대한 보존하면서 원하는 부위로의 집중적 치료가 가능해지면서 특히 노인에게서 유용한 대안이 될 수 있을 것으로 생각된다.

Radiotherapy, as a major 3 standard treatment for cancer, traditionally it has been useful treatment that aim of curative or palliative setting. In addition to some proliferative or inflammatory benign disease are also included in field of radiotherapy. Unlike cancer, in the case of benign disease, it shows good treatment result from usage of some medication, conservative management or surgery. But if fail of these treatment or impossible, low dose radiotherapy is use adjuvant or replacement treatment so that there are no harmful side effect result in safety and easy management for reduce pain or recurrence. Recently, the technical advances in radiotherapy that have been achieved make preservation of normal tissue and the clinical application of high precision radiotherapy focus to selective lesions is possible, and it makes useful treatment in senile patients especially.

키워드

참고문헌

  1. A M Luis, "Radiotherapy for non-malignant diseases," Reports of practical oncology and radiotherapy, Vol. 1, No. 8, pp. S14-S15, 2013.
  2. EJ Hall, A Giaccia. Radiobiology for the Radiologist. Philadelphia: Lippincott Williams and Wilkins, 2011.
  3. GA Viani , LI De Fendi , EC Fonseca ,EJ Stefano . "Low or high fractionation dose beta-radiotherapy for pterygium? A randomized clinical trial," International Journal of Radiation Oncology Biology and Physics, Vol. 82, No.2, pp. 181-185, 2012. https://doi.org/10.1016/j.ijrobp.2010.11.017
  4. IM Jurgenliemk-Schulz, LJ Hartman, JM Roesink, RJ Tersteeg, van Der Tweel I, HB Kal, MP Mourits, HK Wyrdeman. "Prevention of pterygium recurrence by postoperative single-dose beta- irradiation: a prospective randomized clinical double-blind trial," International Journal of Radiation Oncology Biology and Physics, Vol. 59, No. 4, pp. 1138-1147, 2004. https://doi.org/10.1016/j.ijrobp.2003.12.021
  5. GB Bartley, V Fatourechi, EF Kadrmas, SJ Jacobsen, DM Ilstrup, JA Garrity, CA Gorman. "The incidence of Graves' ophthalmopathy in Olmsted County, Minnesota," American Jounal of Ophthalmology, Vol. 120, No. 4, pp. 511-517. 1995. https://doi.org/10.1016/S0002-9394(14)72666-2
  6. P Perros ,C Neoh ,J Dickinson. "Thyroid eye disease," British Medical Journal, Vol. 338: b560, 2009. https://doi.org/10.1136/bmj.b560
  7. MLTanda, L Bartalena. "Efficacy and safety of orbital radiotherapy for Graves' orbitopathy," Journal of Clinical Endocrinology & Metabolism, Vol. 97, No. 11, pp. 3857-3865, 2012. https://doi.org/10.1210/jc.2012-2758
  8. RH Hart ,P Perros. "Glucocorticoids in the medical management of Graves ophthalmopathy," Minerva Endocrinology, Vol. 28, No. 3, pp. 223-231, 2003.
  9. L Bartalena, C Marcocci, ML Tanda, R Rocchi, B Mazzi, G Barbesino, A Pinchera. "Orbital radiotherapy for Graves' ophthalmopathy," Thyroid, Vol.12, No. 3, pp. 245-250, 2002. https://doi.org/10.1089/105072502753600223
  10. H Nakahara, S Noguchi, N Murakami, M Morita, M Tamaru, T Ohnishi, H Hoshi, S Jinnouchi, S Nagamachi, and S Futami, "Graves ophthalmopathy: MR evaluation of 10-Gy versus 24-Gy irradiation combined with systemic corticosteroids," Radiology, Vol. 196, No. 3, pp 857-862, 1995. https://doi.org/10.1148/radiology.196.3.7644656
  11. GJ Kahaly, HP Rosler ,S Pitz ,G Hommel. "Low- versus high-dose radiotherapy for Graves' ophthalmopathy: a randomized, single blind trial," Journal of Journal Clinical Endocrinology & Metabolism, Vol. 85, No. 1, pp 102-108, 2000.
  12. J Rootman. "Why 'orbital pseudotumour' is no longer a useful concept," British Journal of Ophthalmology, Vol. 82, No. 4, pp. 339-340, 1998. https://doi.org/10.1136/bjo.82.4.339
  13. C Matthiesen, C Bogardus Jr, JS Thompson, B Farris, L Hildebrand, B Wilkes, E Syzek, O Algan, S Ahmad, T Herman, "The efficacy of radiotherapy in the treatment of orbital pseudotumor," International Journal of Radiattion Oncology Biology and Physics, Vol. 79, No. 5, pp. 1496-1502, 2011. https://doi.org/10.1016/j.ijrobp.2009.12.071
  14. MC Smitt, SS Donaldson, "Radiation therapy for benign disease of the orbit," Seminars in Radiation Oncology, Vol. 9, No. 2, pp. 179-189, 1999.
  15. N Chirapapaisan, W Chuenkongkaew ,K Pornpanich, S Vangveeravong, "Orbital pseudotumor: clinical features and outcomes," Asian Pacific Journal of Allergy and Immunology, Vol. 25, No. 4, pp. 215-218, 2007.
  16. WM Mendenhall, AM Lessner, "Orbital pseudotumor," American Journal of Clinical Oncology, Vol. 33, No. 3, pp. 304-306, 2010.
  17. I Mombaerts,RO Schlingemann ,RGoldschmeding, L Koornneef, "Are systemic corticosteroids useful in the management of orbital pseudotumors?",Ophthalmology, Vol. 103, No. 3, pp. 521-528, 1996. https://doi.org/10.1016/S0161-6420(96)30663-5
  18. DH Char, T Miller, "Orbital pseudotumor.Fine-needle aspiration biopsy and response to therapy," Ophthalmology, Vol. 100, No. 11, pp. 1702-1710, 1993. https://doi.org/10.1016/S0161-6420(93)31414-4
  19. BB Mittal, M Deutsch, J Kennerdell, B Johnson, "Paraocular lymphoid tumors," Radiology, Vol. 159, No. 3, pp. 793-796, 1986. https://doi.org/10.1148/radiology.159.3.3704159
  20. JJ Shaffer, SC Taylor, F Cook-Bolden, "Keloidal scars: A review with a critical look at therapeutic options," Journal of the American Academy of Dermatology, Vol. 46, No. 2 (Suppl Understanding), pp. S63-S97, 2002. https://doi.org/10.1067/mjd.2002.120788
  21. BJ McCoy, IK Cohen, "Effects of various sera on growth kinetics and collagen synthesis by keloid and normal dermal fibroblasts," Plastic and Reconstructive Surgery, Vol. 67, No. 4, pp. 505-510, 1981. https://doi.org/10.1097/00006534-198104000-00014
  22. WT Lawrence, "In search of the optimal treatment of keloids: report of a series and a review of the literature," Annals of Plastic Surgery, Vol.27, No. 2, pp. 164-178, 1991. https://doi.org/10.1097/00000637-199108000-00012
  23. R Ragoowansi, PG Cornes, JP Glees, BW Powell, AL Moss, "Ear-lobe keloids: treatment by a protocol of surgical excision and immediate postoperative adjuvant radiotherapy," British Journal of Plastic Surgery, Vol. 54, No. 6, pp. 504-508, 2001. https://doi.org/10.1054/bjps.2001.3656
  24. JJ Kovalic, CA Perez, "Radiation therapy following keloidectomy: A 20-year experience," International Journal of Radiation Oncology Biology and Physics, Vol. 17, No. 1, pp. 77-80, 1989.
  25. DM Warner, F Flowers, FA Ramos-Caro, "Solitary keratoacanthoma (squamous cell carcinoma) :Surgical management," International Journal of Dermatology, Vol. 34, No. 1, pp. 17-9.1995. https://doi.org/10.1111/j.1365-4362.1995.tb04368.x
  26. B Donahue, JS Cooper, S Rush, "Treatment of aggressive keratoacanthomas by radiotherapy." Journal of the American Academy of Dermatology, Vol. 23, No. (3 Pt 1), pp. 489-93, 1990. https://doi.org/10.1016/0190-9622(90)70247-F
  27. FF Naraghi, TA DeCoster, MS Moneim, RA Miller, D Rivero, "Heterotopic ossification," Orthopedics, Vol. 19, No. 1, pp. 145-151, 1996.
  28. BC Neal, A Rodgers, T Clark, H Gray, IR Reid, L Dunn, SW Macmahon, "A systematic survey of 13 randomized trials of non-steroidal anti-inflammatory drugs for the prevention of heterotopic bone formation after major hip surgery," Acta Orthopaedica Scandinavica, Vol. 72, No. 2, pp. 122-128, 2000.
  29. M Fransen, C Anderson, J Douglas, S MacMahon, B Neal, R Norton, M Woodward, ID Cameron, R Crawford, SK Lo, G Tregonning, M Windolf, "Safety and efficacy of routine postoperative ibuprofen for pain and disability related to ectopic bone formation after hip replacement surgery (HIPAID): randomised controlled trial," British Medical Journal, Vol. 333(7567): 519, 2006. https://doi.org/10.1136/bmj.38925.471146.4F
  30. MH Seegenschmiedt, L Keilholz, P Martus, A Goldmann, R Wolfel, F Henning, R Sauer, "Prevention of heterotopic ossification about the hip: Final results of two randomized trials in 410 patients using either preoperative or postoperative radiation therapy," International Journal of Radiation Oncology Biology and Physics, Vol. 39, No. 1, pp. 161-171, 1997. https://doi.org/10.1016/S0360-3016(97)00285-X
  31. SJ Gregoritch, M Chadha, VD Pelligrini, P Rubin, DA Kantorowitz, "Randomized trial comparing preoperative versus postoperative irradiation for prevention of heterotopic ossification following prosthetic total hip replacement: Preliminary results," International Journal of Radiation Oncology Biology and Physics, Vol. 31, No. 1, pp. 55-62. 1994.
  32. JL Doppman, EH. Oldfield, JD Heiss, "Symptomatic Vertebral Hemangiomas: Treatment by Means of Direct Intralesional Injection of Ethanol," Radiology, Vol. 214, No. 1, pp. 341-348, 2000. https://doi.org/10.1148/radiology.214.2.r00fe46341
  33. R Heyd, MH Seegenschmiedt, D Rades, C Winkler, HT Eich, F Bruns. German Cooperative Group on Radiotherapy for Benign Diseases, "Radiotherapy for symptomatic vertebral hemangiomas: results of a multi center study and literature review," International Journal of Radiation Oncology Biology and Physics ,Vol. 77, No. 1, pp. 217-25, 2010. https://doi.org/10.1016/j.ijrobp.2009.04.055
  34. D Rades , A Bajrovic, W Alberti, V Rudat, "Is there a dose-effect relationship for the treatment of symptomatic vertebral hemangioma?," International Journal of Radiation Oncology Biology and Physics ,Vol. 55, No. 2, pp. 178-81, 2003. https://doi.org/10.1016/S0360-3016(02)03734-3
  35. C Marafko, "Endoscopic partial plantar fasciotomy as a treatment alternative in plantar fasciitis," Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca, Vol. 74, No. 6, pp. 406-409, 2007.
  36. OJ Ott, C Jeremias, US Gaipl, B Frey, M Schmidt, R Fietkau, "Radiotherapy forcalcaneodynia. Results of a single centerprospective randomized dose optimizationtrial," Strahlentherapie und Onkologie Vol. 189, No. 3, pp. 329-34, 2013. https://doi.org/10.1007/s00066-012-0256-3
  37. LM De Angelis, "Brain tumors," New England Journal of Med, Vol. 44, No. 2, pp. 114-123, 2001.
  38. D Simpson, "The recurrence of intracranial meningiomas after surgical treatment," Journal of Neurology, Neurosurgery &Psychiatry, Vol. 20, No. 1, pp. 22-39, 1957. https://doi.org/10.1136/jnnp.20.1.22
  39. Goldsmith BJ, Wara WM, Wilson CB, Larson DA, "Postoperative irradiation for subtotally resected meningiomas. A retrospective analysis of 140 patients treated from 1967 to 1990," Journal of Neurosurgery, 1994; Vol. 80, No. 2, pp. 195-201, 1994. https://doi.org/10.3171/jns.1994.80.2.0195
  40. R Al-Shahi, JJ Bhattacharya, DG Currie, V Papanastassiou, V Ritchie, RC. Roberts, RJ Sellar, CP Warlow, "Prospective, population-based detection of intracranial vascular malformations in adults: the Scottish Intracranial Vascular Malformation Study (SIVMS)," Stroke, Vol. 34, No. 5, pp. 1163-1169, 2003. https://doi.org/10.1161/01.STR.0000069018.90456.C9
  41. B Pollock. Arteriovenous malformation. In: Chin L, Regine W (eds). Principles and Practice of Stereotactic Radiosurgery. New York: Springer Science and Business Media, 2008.
  42. B Karlsson, C Lindquist, L Steiner, "Prediction of obliteration after gamma knife surgery for cerebral arteriovenous malformations," Neurosurgery, Vol. 40, N0. 3, pp. 425-430; discussion 430-431, 1997. https://doi.org/10.1227/00006123-199703000-00001
  43. JC Flickinger, BE Pollock, D Kondziolka, LD Lunsford, "A dose response analysis of arteriorvenous mailformation obliteration after radiosurgery," International Journal of Radiation Oncology Biology and Physics, Vol. 36, No. 4, pp. 873-879, 1996. https://doi.org/10.1016/S0360-3016(96)00316-1