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Antioxidant Activities of Water Extracts from Different Parts of Lycopus lucidus Turcz. ex Benth.

쉽싸리 부위별 물추출물의 항산화 활성

  • Song, Youn-Jin (Department of Herbal pharmaceutical Science, Joongbu University) ;
  • Chang, Jun-Pok (Department of Herbal pharmaceutical Science, Joongbu University) ;
  • Yoo, Ji-Hyun (Department of Herbal pharmaceutical Science, Joongbu University)
  • 송윤진 (중부대학교 한방제약과학과) ;
  • 장준복 (중부대학교 한방제약과학과) ;
  • 유지현 (중부대학교 한방제약과학과)
  • Received : 2016.10.10
  • Accepted : 2016.11.16
  • Published : 2016.11.30

Abstract

Objectives : This study was performed to investigate the antioxidant activity of water extracts from Lycopus lucidus Turcz. ex Benth. leaves, stems and roots at the $100{\mu}g/m{\ell}$ concentration. Methods : The different part of Lycopus lucidus Turcz. ex Benth. extract was prepared using water. The antioxidant activities of polyphenol contents, total flavonoid contents, DPPH(1,1-diphenyl-2-picrylhydrazyl) free-radical scavenging activity, SOD like activity, hydroxyl radical, ABTS(2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid), $Fe^{2+}$ chelating, and nitrite scavenging activity. Results : The total polyphenol and total flavonoid content of leaves were the highest at $221.85{\mu}g/mg$ and $794.13{\mu}g/mg$, respectively. Electron donating ability was the 79.68% in the water extract from leaves. The ABTS radical scavenging activity of the hot extracts, leaves ${\gg}$ roots > stems was higher in the order. It was shown the highest at 94.53% in the water extract from leaves, which showed a value equal to 94.7% of ascorbic acid. The hydroxyl radical scavenging activity was the highest at 8.07% in the water extract from leaves. SOD like activity and $Fe^{2+}$chelating activity were leaves of 12.3% and 27%, respectively, which were much higher than those of any other parts. The nitrite scavenging ability of extracts was increased at pH 2.5, and those was the highest in leaves of 83.03%. Its were more than twice the 41.61% of BHT. Conclusion : The results suggest that Lycopus lucidus Turcz. ex Benth. can be used as nutraceutical foods and natural antioxidant.

Keywords

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