Nutrition Research and Practice

  • 제10권1호
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  • Pages.67-73
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  • 2016
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  • 1976-1457(pISSN)
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  • 2005-6168(eISSN)
한국영양학회 (The Korean Nutrition Society)
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Association between dietary flavanones intake and lipid profiles according to the presence of metabolic syndrome in Korean women with type 2 diabetes mellitus

  • Oh, Ji Soo (Department of Nutritional Science and Food Management, Ewha Womans University) ;
  • Kim, Hyesook (Department of Nutritional Science and Food Management, Ewha Womans University) ;
  • Vijayakumar, Aswathy (Department of Nutritional Science and Food Management, Ewha Womans University) ;
  • Kwon, Oran (Department of Nutritional Science and Food Management, Ewha Womans University) ;
  • Choi, Young Ju (Huh's Diabetes Clinic & the 21C Diabetes and Vascular Research Institute) ;
  • Huh, Kap Bum (Huh's Diabetes Clinic & the 21C Diabetes and Vascular Research Institute) ;
  • Chang, Namsoo (Department of Nutritional Science and Food Management, Ewha Womans University)
  • 투고 : 2015.04.14
  • 심사 : 2015.09.24
  • 발행 : 2016.02.01
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초록

BACKGROUND/OBJECTIVES: This study was aimed at examining the association between dietary flavanones intake and lipid profiles according to the presence of metabolic syndrome (MetS) in Korean women with type 2 diabetes mellitus (T2DM). SUBJECTS/METHODS: A cross-sectional analysis was performed among 502 female T2DM patients (non-MetS group; n = 129, MetS group; n = 373) who were recruited from the Huh's Diabetes Clinic in Seoul, Korea between 2005 and 2011. The dietary intake was assessed by a validated semi-quantitative food frequency questionnaire (FFQ) and the data was analyzed using the Computer Aided Nutritional Analysis program (CAN-Pro) version 4.0 software. The intake of flavanones was estimated on the basis of the flavonoid database. RESULTS: In the multiple linear regression analysis after adjustment for confounding factors, daily flavanones intake was negatively associated with CVD risk factors such as total cholesterol, LDL-cholesterol, and apoB and apoB/apoA1 ratio only in the MetS group but not in the non-MetS group. Multiple logistic regression analysis revealed that the odds ratio for a higher apoB/apoA1 ratio above the median (${\geq}0.74$) was significantly low in the $4^{th}$ quartile compared to that in the $1^{st}$ quartile of dietary flavanones intake [OR: 0.477, 95% CI: 0.255-0.894, P for trend = 0.0377] in the MetS group. CONCLUSIONS: Dietary flavanones intake was inversely associated with the apoB/apoA1 ratio, suggesting a potential protective effect of flavanones against CVD in T2DM women with MetS.

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참고문헌

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