Journal of the Korean Society for Precision Engineering (한국정밀공학회지)

Korean Society for Precision Engineering (한국정밀공학회)
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Deformation Measurement of Polymer Scaffold Using Particle Image Analysis

입자 영상 해석을 이용한 고분자 지지체 변형 측정

  • Kang, Min Je (Department of Mechanical Engineering, Myoungji University) ;
  • Oh, Sang Hoon (Department of Mechanical Engineering, Myoungji University) ;
  • Rhee, Kyehan (Department of Mechanical Engineering, Myoungji University)
  • 강민제 (명지대학교 기계공학과) ;
  • 오상훈 (명지대학교 기계공학과) ;
  • 이계한 (명지대학교 기계공학과)
  • Received : 2015.11.15
  • Accepted : 2015.12.24
  • Published : 2016.01.01
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Abstract

Polydimethylsiloxane (PDMS) is used as a scaffold for cell culture. Because both the stress and strain acting on the substrate and the hemodynamic environment are important for studying mechano-transduction of cellular function, the traction force of the surface of a substrate has been measured using fluorescence images of particle distribution. In this study, deformation of the cross-sectional plane of a PDMS block was measured by correlating particle image distributions to validate the particle image strain measurement technique. Deformation was induced by a cone indentor and a shearing parallel plate. Measured deformations from particle image distributions were in agreement with the results of a computational structure analysis using the finite-element method. This study demonstrates that the particle image correlation method facilitates measurement of deformation of a polymer scaffold in the cross-sectional plane.

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References

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