References
- Grossmann ME, Ray A, Nkhata KJ, Malakhov DA, Rogozina OP, Dogan S, Cleary MP. Obesity and breast cancer: status of leptin and adiponectin in pathological processes. Cancer Metastasis Rev 2010;29:641-53. https://doi.org/10.1007/s10555-010-9252-1
- Rohan TE, Heo M, Choi L, Datta M, Freudenheim JL, Kamensky V, Ochs-Balcom HM, Qi L, Thomson CA, Vitolins MZ, Wassertheil-Smoller S, Kabat GC. Body fat and breast cancer risk in postmenopausal women: a longitudinal study. J Cancer Epidemiol 2013;2013:754815.
- Calle EE, Rodriguez C, Walker-Thurmond K, Thun MJ. Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. N Engl J Med 2003;348:1625-38. https://doi.org/10.1056/NEJMoa021423
- Eliassen AH, Colditz GA, Rosner B, Willett WC, Hankinson SE. Adult weight change and risk of postmenopausal breast cancer. JAMA 2006;296:193-201. https://doi.org/10.1001/jama.296.2.193
- World Cancer Research Fund (GB); American Institute for Cancer Research. Food, Nutrition, Physical Activity, and the Prevention of Cancer: a Global Perspective. Washington D.C.: American Institute for Cancer Research; 2007.
- World Cancer Research Fund International, Continuous Update Project (GB). Diet, Nutrition, Physical Activity, and the Breast Cancer Survivors. London: World Cancer Research Fund International; 2014.
- Brennan SF, Woodside JV, Lunny PM, Cardwell CR, Cantwell MM. Dietary fat and breast cancer mortality: a systematic review and meta-analysis. Crit Rev Food Sci Nutr Forthcoming 2015..
- Mourouti N, Kontogianni MD, Papavagelis C, Panagiotakos DB. Diet and breast cancer: a systematic review. Int J Food Sci Nutr 2015;66:1-42. https://doi.org/10.3109/09637486.2014.950207
- Demir B, Ozturkoglu E, Solaroglu A, Baskan B, Kandemir O, Karabulut E, Haberal A. The effects of estrogen therapy and estrogen combined with different androgenic progestins on carbohydrate and lipid metabolism in overweight-obese younger postmenopausal women. Gynecol Endocrinol 2008;24:347-53. https://doi.org/10.1080/01443610802043066
- Jensen LB, Vestergaard P, Hermann AP, Gram J, Eiken P, Abrahamsen B, Brot C, Kolthoff N, Sorensen OH, Beck-Nielsen H, Nielsen SP, Charles P, Mosekilde L. Hormone replacement therapy dissociates fat mass and bone mass, and tends to reduce weight gain in early postmenopausal women: a randomized controlled 5-year clinical trial of the Danish Osteoporosis Prevention Study. J Bone Miner Res 2003;18:333-42. https://doi.org/10.1359/jbmr.2003.18.2.333
- Cooke PS, Naaz A. Role of estrogens in adipocyte development and function. Exp Biol Med (Maywood) 2004;229:1127-35. https://doi.org/10.1177/153537020422901107
- D'Eon TM, Souza SC, Aronovitz M, Obin MS, Fried SK, Greenberg AS. Estrogen regulation of adiposity and fuel partitioning. Evidence of genomic and non-genomic regulation of lipogenic and oxidative pathways. J Biol Chem 2005;280:35983-91. https://doi.org/10.1074/jbc.M507339200
- Field FJ, Born E, Murthy S, Mathur SN. Polyunsaturated fatty acids decrease the expression of sterol regulatory element-binding protein-1 in CaCo-2 cells: effect on fatty acid synthesis and triacylglycerol transport. Biochem J 2002;368:855-64. https://doi.org/10.1042/bj20020731
- Horton JD. Sterol regulatory element-binding proteins: transcriptional activators of lipid synthesis. Biochem Soc Trans 2002;30:1091-5. https://doi.org/10.1042/bst0301091
- Kuhl J, Hilding A, Ostenson CG, Grill V, Efendic S, Bavenholm P. Characterisation of subjects with early abnormalities of glucose tolerance in the Stockholm Diabetes Prevention Programme: the impact of sex and type 2 diabetes heredity. Diabetologia 2005;48:35-40. https://doi.org/10.1007/s00125-004-1614-1
- Macotela Y, Boucher J, Tran TT, Kahn CR. Sex and depot differences in adipocyte insulin sensitivity and glucose metabolism. Diabetes 2009;58:803-12. https://doi.org/10.2337/db08-1054
- Saengsirisuwan V, Pongseeda S, Prasannarong M, Vichaiwong K, Toskulkao C. Modulation of insulin resistance in ovariectomized rats by endurance exercise training and estrogen replacement. Metabolism 2009;58:38-47. https://doi.org/10.1016/j.metabol.2008.08.004
- Gao H, Bryzgalova G, Hedman E, Khan A, Efendic S, Gustafsson JA, Dahlman-Wright K. Long-term administration of estradiol decreases expression of hepatic lipogenic genes and improves insulin sensitivity in ob/ob mice: a possible mechanism is through direct regulation of signal transducer and activator of transcription 3. Mol Endocrinol 2006;20:1287-99. https://doi.org/10.1210/me.2006-0012
- Vona-Davis L, Howard-McNatt M, Rose DP. Adiposity, type 2 diabetes and the metabolic syndrome in breast cancer. Obes Rev 2007;8:395-408. https://doi.org/10.1111/j.1467-789X.2007.00396.x
- Jouyandeh Z, Nayebzadeh F, Qorbani M, Asadi M. Metabolic syndrome and menopause. J Diabetes Metab Disord 2013;12:1. https://doi.org/10.1186/2251-6581-12-1
- Frasca F, Pandini G, Sciacca L, Pezzino V, Squatrito S, Belfiore A, Vigneri R. The role of insulin receptors and IGF-I receptors in cancer and other diseases. Arch Physiol Biochem 2008;114:23-37. https://doi.org/10.1080/13813450801969715
- Kim HJ, Lee HO, Min DB. Effects and prooxidant mechanisms of oxidized alpha-tocopherol on the oxidative stability of soybean oil. J Food Sci 2007;72:C223-30. https://doi.org/10.1111/j.1750-3841.2007.00339.x
- Hong J, Holcomb VB, Kushiro K, Nunez NP. Estrogen inhibits the effects of obesity and alcohol on mammary tumors and fatty liver. Int J Oncol 2011;39:1443-53.
- Blume-Jensen P, Hunter T. Oncogenic kinase signalling. Nature 2001;411:355-65. https://doi.org/10.1038/35077225
- Reeves PG, Nielsen FH, Fahey GC Jr. AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J Nutr 1993;123:1939-51. https://doi.org/10.1093/jn/123.11.1939
- Park SY, Kim JS, Seo YR, Sung MK. Effects of diet-induced obesity on colitis-associated colon tumor formation in A/J mice. Int J Obes (Lond) 2012;36:273-80. https://doi.org/10.1038/ijo.2011.83
- Stephenson GD, Rose DP. Breast cancer and obesity: an update. Nutr Cancer 2003;45:1-16. https://doi.org/10.1207/S15327914NC4501_1
- Healy LA, Ryan AM, Carroll P, Ennis D, Crowley V, Boyle T, Kennedy MJ, Connolly E, Reynolds JV. Metabolic syndrome, central obesity and insulin resistance are associated with adverse pathological features in postmenopausal breast cancer. Clin Oncol (R Coll Radiol) 2010;22:281-8. https://doi.org/10.1016/j.clon.2010.02.001
- Nadal A, Alonso-Magdalena P, Soriano S, Ropero AB, Quesada I. The role of oestrogens in the adaptation of islets to insulin resistance. J Physiol 2009;587:5031-7. https://doi.org/10.1113/jphysiol.2009.177188
- Hong J, Stubbins RE, Smith RR, Harvey AE, Nunez NP. Differential susceptibility to obesity between male, female and ovariectomized female mice. Nutr J 2009;8:11. https://doi.org/10.1186/1475-2891-8-11
- Hakkak R, MacLeod S, Shaaf S, Holley AW, Simpson P, Fuchs G, Jo CH, Kieber-Emmons T, Korourian S. Obesity increases the incidence of 7,12-dimethylbenz(a)anthracene-induced mammary tumors in an ovariectomized Zucker rat model. Int J Oncol 2007;30:557-63.
- Sylvester PW, Ip C, Ip MM. Effects of high dietary fat on the growth and development of ovarian-independent carcinogen-induced mammary tumors in rats. Cancer Res 1986;46:763-9.
- Costa I, Solanas M, Escrich E. Histopathologic characterization of mammary neoplastic lesions induced with 7,12 dimethylbenz (alpha)anthracene in the rat: a comparative analysis with human breast tumors. Arch Pathol Lab Med 2002;126:915-27.
- Hwang IK, Kim IY, Kim DW, Yoo KY, Kim YN, Yi SS, Won MH, Lee IS, Yoon YS, Seong JK. Strain-specific differences in cell proliferation and differentiation in the dentate gyrus of C57BL/6N and C3H/HeN mice fed a high fat diet. Brain Res 2008;1241:1-6. https://doi.org/10.1016/j.brainres.2008.08.024
- Suganami T, Mieda T, Itoh M, Shimoda Y, Kamei Y, Ogawa Y. Attenuation of obesity-induced adipose tissue inflammation in C3H/HeJ mice carrying a Toll-like receptor 4 mutation. Biochem Biophys Res Commun 2007;354:45-9. https://doi.org/10.1016/j.bbrc.2006.12.190
- Lim DW, Lee Y, Kim YT. Preventive effects of Citrus unshiu peel extracts on bone and lipid metabolism in OVX rats. Molecules 2014;19:783-94. https://doi.org/10.3390/molecules19010783
- Choi JS, Koh IU, Song J. Genistein reduced insulin resistance index through modulating lipid metabolism in ovariectomized rats. Nutr Res 2012;32:844-55. https://doi.org/10.1016/j.nutres.2012.10.002
- Lane HW, Keith RE, Strahan S, White MT. The effect of diet, exercise and 7,12-dimethylbenz(a)anthracene on food intake, body composition and carcass energy levels in virgin female BALB/c mice. J Nutr 1991;121:1876-82. https://doi.org/10.1093/jn/121.11.1876
- Ojeswi BK, Khoobchandani M, Hazra DK, Srivastava MM. Protective effect of Thuja occidentalis against DMBA-induced breast cancer with reference to oxidative stress. Hum Exp Toxicol 2010;29:369-75. https://doi.org/10.1177/0960327110364150
- Gambacciani M, Ciaponi M, Cappagli B, Piaggesi L, De Simone L, Orlandi R, Genazzani AR.Body weight, body fat distribution, and hormonal replacement therapy in early postmenopausal women. J Clin Endocrinol Metab 1997;82:414-7. https://doi.org/10.1210/jcem.82.2.3735
- Asp ML, Tian M, Wendel AA, Belury MA. Evidence for the contribution of insulin resistance to the development of cachexia in tumor-bearing mice. Int J Cancer 2010;126:756-63. https://doi.org/10.1002/ijc.24784
- Suba Z. Circulatory estrogen level protects against breast cancer in obese women. Recent Pat Anticancer Drug Discov 2013;8:154-67. https://doi.org/10.2174/1574892811308020004
- Koricanac G, Milosavljevic T, Stojiljkovic M, Zakula Z, Ribarac-Stepic N, Isenovic ER. Insulin signaling in the liver and uterus of ovariectomized rats treated with estradiol. J Steroid Biochem Mol Biol 2008;108:109-16. https://doi.org/10.1016/j.jsbmb.2007.06.001
- Swislocki A, Burgie ES, Rodnick KJ. Effects of ovariectomy on indices of insulin resistance, hypertension, and cardiac energy metabolism in middle-aged spontaneously hypertensive rats (SHR). Horm Metab Res 2002;34:516-22. https://doi.org/10.1055/s-2002-34792
- Carr MC. The emergence of the metabolic syndrome with menopause. J Clin Endocrinol Metab 2003;88:2404-11. https://doi.org/10.1210/jc.2003-030242
- Pfeilschifter J, Koditz R, Pfohl M, Schatz H. Changes in proinflammatory cytokine activity after menopause. Endocr Rev 2002;23:90-119. https://doi.org/10.1210/edrv.23.1.0456
- Gu JW, Young E, Patterson SG, Makey KL, Wells J, Huang M, Tucker KB, Miele L. Postmenopausal obesity promotes tumor angiogenesis and breast cancer progression in mice. Cancer Biol Ther 2011;11:910-7. https://doi.org/10.4161/cbt.11.10.15473
- Nunez NP, Perkins SN, Smith NC, Berrigan D, Berendes DM, Varticovski L, Barrett JC, Hursting SD. Obesity accelerates mouse mammary tumor growth in the absence of ovarian hormones. Nutr Cancer 2008;60:534-41. https://doi.org/10.1080/01635580801966195
- Asselin J, Labrie F. Effects of estradiol and prolactin on steroid receptor levels in 7,12-dimethylbenz(a)anthracene-induced mammary tumors and uterus in the rat. J Steroid Biochem 1978;9:1079-82. https://doi.org/10.1016/0022-4731(78)90035-3
- Sasaki GH, Leung BS. On the mechanism of hormone action in 7,12 dimethylbenz(a)anthracene-induced mammary tumor. I. Prolactin and progesterone effects on estrogen receptor in vitro. Cancer 1975;35:645-51. https://doi.org/10.1002/1097-0142(197503)35:3<645::AID-CNCR2820350316>3.0.CO;2-T
- Dao TL. The role of ovarian hormones in initiating the induction of mammary cancer in rats by polynuclear hydrocarbons. Cancer Res 1962;22:973-81.
- Rose DP, Gilhooly EM, Nixon DW. Adverse effects of obesity on breast cancer prognosis, and the biological actions of leptin (review). Int J Oncol 2002;21:1285-92.
- Daling JR, Malone KE, Doody DR, Johnson LG, Gralow JR, Porter PL. Relation of body mass index to tumor markers and survival among young women with invasive ductal breast carcinoma. Cancer 2001;92:720-9. https://doi.org/10.1002/1097-0142(20010815)92:4<720::AID-CNCR1375>3.0.CO;2-T
- Belfiore A, Frasca F. IGF and insulin receptor signaling in breast cancer. J Mammary Gland Biol Neoplasia 2008;13:381-406. https://doi.org/10.1007/s10911-008-9099-z
- Wysocki PJ, Wierusz-Wysocka B. Obesity, hyperinsulinemia and breast cancer: novel targets and a novel role for metformin. Expert Rev Mol Diagn 2010;10:509-19. https://doi.org/10.1586/erm.10.22
- Clark AS, West K, Streicher S, Dennis PA. Constitutive and inducible Akt activity promotes resistance to chemotherapy, trastuzumab, or tamoxifen in breast cancer cells. Mol Cancer Ther 2002;1:707-17.
- Woo SL, Xu H, Li H, Zhao Y, Hu X, Zhao J, Guo X, Guo T, Botchlett R, Qi T, Pei Y, Zheng J, Xu Y, An X, Chen L, Chen L, Li Q, Xiao X, Huo Y, Wu C. Metformin ameliorates hepatic steatosis and inflammation without altering adipose phenotype in diet-induced obesity. PLoS One 2014;9:e91111. https://doi.org/10.1371/journal.pone.0091111
- Wohlers LM, Sweeney SM, Ward CW, Lovering RM, Spangenburg EE. Changes in contraction-induced phosphorylation of AMP-activated protein kinase and mitogen-activated protein kinases in skeletal muscle after ovariectomy. J Cell Biochem 2009;107:171-8. https://doi.org/10.1002/jcb.22113
- Tiainen M, Vaahtomeri K, Ylikorkala A, Makela TP. Growth arrest by the LKB1 tumor suppressor: induction of p21(WAF1/CIP1). Hum Mol Genet 2002;11:1497-1504. https://doi.org/10.1093/hmg/11.13.1497
- Jones RG, Plas DR, Kubek S, Buzzai M, Mu J, Xu Y, Birnbaum MJ, Thompson CB. AMP-activated protein kinase induces a p53-dependent metabolic checkpoint. Mol Cell 2005;18:283-93. https://doi.org/10.1016/j.molcel.2005.03.027
- Chapuis N, Tamburini J, Green AS, Willems L, Bardet V, Park S, Lacombe C, Mayeux P, Bouscary D. Perspectives on inhibiting mTOR as a future treatment strategy for hematological malignancies. Leukemia 2010;24:1686-99. https://doi.org/10.1038/leu.2010.170
- Kim JY, Jo KJ, Kim BJ, Baik HW, Lee SK. 17beta-estradiol induces an interaction between adenosine monophosphate-activated protein kinase and the insulin signaling pathway in 3T3-L1 adipocytes. Int J Mol Med 2012;30:979-85. https://doi.org/10.3892/ijmm.2012.1070
- McInnes KJ, Brown KA, Hunger NI, Simpson ER. Regulation of LKB1 expression by sex hormones in adipocytes. Int J Obes (Lond) 2012;36:982-5. https://doi.org/10.1038/ijo.2011.172
- Kim JY, Jo KJ, Kim OS, Kim BJ, Kang DW, Lee KH, Baik HW, Han MS, Lee SK. Parenteral 17beta-estradiol decreases fasting blood glucose levels in non-obese mice with short-term ovariectomy. Life Sci 2010;87:358-66. https://doi.org/10.1016/j.lfs.2010.07.009
- Mita MM, Mita A, Rowinsky EK. The molecular target of rapamycin (mTOR) as a therapeutic target against cancer. Cancer Biol Ther 2003;2:S169-77.
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