The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
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A Case of Gastrointestinal Sarcoidosis without Pulmonary Involvement

폐침범 없이 위장관 전체에 발현된 유육종증 1예

  • Kim, Bo Young (Departments of Internal Medicine, Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine) ;
  • Kim, So Ra (Departments of Internal Medicine, Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine) ;
  • Hwang, Jiyoung (Departments of Radiology, Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine) ;
  • Jin, So-Young (Departments of Pathology, Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine) ;
  • Kim, Hyun-Sook (Departments of Internal Medicine, Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine)
  • 김보영 (순천향대학교 의과대학 순천향대학교병원 내과) ;
  • 김소라 (순천향대학교 의과대학 순천향대학교병원 내과) ;
  • 황지영 (순천향대학교 의과대학 순천향대학교병원 영상의학과) ;
  • 진소영 (순천향대학교 의과대학 순천향대학교병원 병리과) ;
  • 김현숙 (순천향대학교 의과대학 순천향대학교병원 내과)
  • Published : 20150000
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Abstract

Sarcoidosis is a multisystemic granulomatous disease of unknown etiology that is based on the presence of non-caseating granulomas. Sarcoidosis commonly involves the lungs, skin, and eyes. Gastrointestinal tract involvement in sarcoidosis is uncommon. Gastrointestinal tract sarcoidosis commonly occurs subclinically, with clinical manifestations present in only 0.1-0.9% of patients with the disease. There are rare case reports of an individual with symptomatic gastrointestinal sarcoidosis. In Korea, gastrointestinal sarcoidosis without pulmonary involvement has not been reported previously. Here, we describe a case of gastrointestinal sarcoidosis in a 37-year-old male with symptoms of weight loss, fever, and abdominal pain. He was diagnosed based on the presence of non-caseating epithelioid granulomas in the stomach, duodenum, and colon by multiple biopsies.

위장관 침범 유육종증은 드물며 무증상을 보이는 경우가 많아 간과하기 쉽다. 조직학적 육아종 형성을 일으킬 수 있는 다른 질환과 감별을 요하며 조직학적 확진을 통해서 진단하여야 한다. 저자 등은 폐 침범없는 위장관 유육종증을 내시경하 생검을 통해 비건락성 육아종을 확인하여 진단하고 치료하였다. 이는 국내에서는 드문 증례이므로 문헌 고찰과 함께 이를 보고하는 바이다.

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