The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
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Nonerosive Reflux Disease

비미란성 역류 질환

  • Kim, Tae Suk (Department of Internal Medicine, Kangwon National University School of Medicine) ;
  • Park, Sung Chul (Department of Internal Medicine, Kangwon National University School of Medicine) ;
  • Lee, Sung Joon (Department of Internal Medicine, Kangwon National University School of Medicine)
  • 김태석 (강원대학교 의학전문대학원 내과학교실) ;
  • 박성철 (강원대학교 의학전문대학원 내과학교실) ;
  • 이성준 (강원대학교 의학전문대학원 내과학교실)
  • Published : 20150000
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Abstract

Nonerosive reflux disease (NERD) is a distinct presentation of gastroesophageal reflux disease (GERD). NERD is commonly defined as the presence of classical GERD symptoms in the absence of esophageal mucosal erosions/breaks on upper endoscopy. Within the spectrum of GERD, the pathophysiological and clinical characteristics distinguishing NERD and erosive esophagitis remain a matter for debate. Recent research on NERD has focused on understanding the pathophysiology and natural history. Given the increased incidence of NERD in Korea, we reviewed the concept of NERD and its relationship to GERD and functional gastrointestinal disorders.

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