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A HYPEREOSINOPHILIC SYNDROME WITH CARDIAC INVOLVEMENT FROM THROMBOTIC STAGE TO FIBROTIC STAGE

  • KIM, NAM KYUN (DIVISION OF CARDIOLOGY, DEPARTMENT OF INTERNAL MEDICINE, KYUNGPOOK NATIONAL UNIVERSITY SCHOOL OF MEDICINE) ;
  • KIM, CHANG-YEON (DIVISION OF CARDIOLOGY, DEPARTMENT OF INTERNAL MEDICINE, KYUNGPOOK NATIONAL UNIVERSITY SCHOOL OF MEDICINE) ;
  • KIM, JAE HEE (DIVISION OF CARDIOLOGY, DEPARTMENT OF INTERNAL MEDICINE, KYUNGPOOK NATIONAL UNIVERSITY SCHOOL OF MEDICINE) ;
  • JANG, SE YONG (DIVISION OF CARDIOLOGY, DEPARTMENT OF INTERNAL MEDICINE, KYUNGPOOK NATIONAL UNIVERSITY SCHOOL OF MEDICINE) ;
  • BAE, MYUNG HWAN (DIVISION OF CARDIOLOGY, DEPARTMENT OF INTERNAL MEDICINE, KYUNGPOOK NATIONAL UNIVERSITY SCHOOL OF MEDICINE) ;
  • LEE, JANG HOON (DIVISION OF CARDIOLOGY, DEPARTMENT OF INTERNAL MEDICINE, KYUNGPOOK NATIONAL UNIVERSITY SCHOOL OF MEDICINE) ;
  • YANG, DONG HEON (DIVISION OF CARDIOLOGY, DEPARTMENT OF INTERNAL MEDICINE, KYUNGPOOK NATIONAL UNIVERSITY SCHOOL OF MEDICINE) ;
  • PARK, HUN SIK (DIVISION OF CARDIOLOGY, DEPARTMENT OF INTERNAL MEDICINE, KYUNGPOOK NATIONAL UNIVERSITY SCHOOL OF MEDICINE) ;
  • CHO, YONGKEUN (DIVISION OF CARDIOLOGY, DEPARTMENT OF INTERNAL MEDICINE, KYUNGPOOK NATIONAL UNIVERSITY SCHOOL OF MEDICINE) ;
  • CHAE, SHUNG CHULL (DIVISION OF CARDIOLOGY, DEPARTMENT OF INTERNAL MEDICINE, KYUNGPOOK NATIONAL UNIVERSITY SCHOOL OF MEDICINE)
  • Received : 2014.09.15
  • Accepted : 2015.05.19
  • Published : 2015.06.27

Abstract

Cardiac involvement is a major cause of morbidity and mortality in hypereosinophilic syndrome (HES). It is classified into 3 stages by the degree of eosinophils-mediated heart injury; acute necrotic stage, thrombotic stage, and fibrotic stage. Nonetheless, definitive evidence that each patient passes sequentially through these stages is lacking. We present a case of 48-year-old male patient with dyspnea and peripheral edema who underwent valve replacement surgery due to severe mitral regurgitation. After the valve replacement, HES with cardiac involvement in the thrombotic stage was diagnosed. In the follow-up study, the patient progressed into fibrotic stage of HES.

Keywords

References

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Cited by

  1. Current Diagnostic and Therapeutic Aspects of Eosinophilic Myocarditis vol.2016, pp.None, 2015, https://doi.org/10.1155/2016/2829583
  2. Left ventricular rotational mechanics in hypereosinophilic syndrome-Analysis from the three‐dimensional speckle‐tracking echocardiographic MAGYAR‐Path Study vol.36, pp.11, 2015, https://doi.org/10.1111/echo.14517