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SUPERIOR VENA CAVA ECHOCARDIOGRAPHY AS A SCREENING TOOL TO PREDICT CARDIOVASCULAR IMPLANTABLE ELECTRONIC DEVICE LEAD FIBROSIS

  • YAKISH, S. JEFFREY (DEPARTMENT OF MEDICINE, DREXEL UNIVERSITY COLLEGE OF MEDICINE) ;
  • NARULA, ARVIN (DEPARTMENT OF MEDICINE, DREXEL UNIVERSITY COLLEGE OF MEDICINE) ;
  • FOLEY, ROBERT (DEPARTMENT OF MEDICINE, DIVISION OF CARDIOLOGY, DREXEL UNIVERSITY COLLEGE OF MEDICINE) ;
  • KOHUT, ANDREW (DEPARTMENT OF MEDICINE, DIVISION OF CARDIOLOGY, DREXEL UNIVERSITY COLLEGE OF MEDICINE) ;
  • KUTALEK, STEVEN (DEPARTMENT OF MEDICINE, DIVISION OF CARDIOLOGY, DREXEL UNIVERSITY COLLEGE OF MEDICINE)
  • 투고 : 2014.12.04
  • 심사 : 2015.03.10
  • 발행 : 2015.03.27

초록

BACKGROUND: Currently there is no noninvasive imaging modality used to risk stratify patients requiring lead extractions. We report the novel use of superior vena cava (SVC) echocardiography to identify lead fibrosis and complex cardiac implantable electronic device (CIED) lead extraction. With an aging population and expanding indications for cardiac device implantation, the ability to deal with the complications associated with chronically implanted device has also increased. METHODS: This was a retrospective analysis of Doppler echocardiography recorded in our outpatient Electrophysiology/Device Clinic office over 6 months. Images from 109 consecutive patients were reviewed. RESULTS: 62% (68/109) did not have a CIED and 38% (41/109) had a CIED. In patients without a CIED, 6% (4/68) displayed turbulent color flow by Doppler in the SVC, while 22% (9/41) of patients with a CIED displayed turbulent flow. Fisher's exact test found a statistically significant difference between the two groups (p value < 0.05). The CIED group was subdivided into 2 groups based on device implant duration (< 2 years vs. ${\geq}2years$). Of the CIED implanted for ${\geq}2years$, 27% (9/33) had turbulent flow in the SVC by Doppler, while no patients (0/8) with implant durations < 2 years demonstrated turbulent flow. Nine patients underwent subsequent lead extraction. A turbulent color pattern successfully identified all 3 patients that had significant fibrosis in the SVC found during extraction. CONCLUSION: Our data suggests that assessing turbulent flow using color Doppler in the SVC may be a valuable noninvasive screening tool prior to lead extraction in predicting complex procedures.

키워드

참고문헌

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피인용 문헌

  1. Cardiovascular implantable electronic device lead extraction: evidence, techniques, results, and future directions vol.31, pp.1, 2015, https://doi.org/10.1097/hco.0000000000000247
  2. Transvenous Lead Extractions: Current Approaches and Future Trends vol.7, pp.3, 2015, https://doi.org/10.15420/aer.2018.33.2
  3. Echocardiographic findings in patients with cardiac implantable electronic devices—analysis of factors predisposing to lead‐associated changes vol.41, pp.1, 2021, https://doi.org/10.1111/cpf.12662
  4. Implant Fibrosis and the Underappreciated Role of Myofibroblasts in the Foreign Body Reaction vol.10, pp.7, 2021, https://doi.org/10.3390/cells10071794