Journal of Cardiovascular Imaging

  • 제23권1호
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  • Pages.10-19
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  • 2015
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  • 2586-7210(pISSN)
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  • 2586-7296(eISSN)
한국심초음파학회 (Korean Society of Echocardiography)
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CARDIOVASCULAR SCREENING IN ASYMPTOMATIC ADOLESCENTS WITH METABOLIC SYNDROME

  • BAE, HYUN KYUNG (DEPARTMENT OF PEDIATRICS, EWHA WOMANS UNIVERSITY SCHOOL OF MEDICINE) ;
  • CHOI, HAN SEUL (DEPARTMENT OF PEDIATRICS, EWHA WOMANS UNIVERSITY SCHOOL OF MEDICINE) ;
  • SOHN, SEJUNG (DEPARTMENT OF PEDIATRICS, EWHA WOMANS UNIVERSITY SCHOOL OF MEDICINE) ;
  • SHIN, HYE-JUNG (DEPARTMENT OF PEDIATRICS, NATIONAL MEDICAL CENTER) ;
  • NAM, JAE-HWAN (DEPARTMENT OF BIOTECHNOLOGY, THE CATHOLIC UNIVERSITY OF KOREA) ;
  • HONG, YOUNG MI (DEPARTMENT OF PEDIATRICS, EWHA WOMANS UNIVERSITY SCHOOL OF MEDICINE)
  • 투고 : 2014.11.21
  • 심사 : 2015.02.27
  • 발행 : 2015.03.27
⟨ 이전 논문 다음 논문 ⟩

초록

BACKGROUND: In recent days, the prevalence of childhood metabolic syndrome (MS) has increased substantially due to the increasing rate of childhood obesity on a global scale. The aims of this study were to detect the important parameters and provide the screening system to prevent cardiovascular disease in adolescents with MS. METHODS: Ninety one male adolescents were divided into two groups based on the presence or absence of MS. Anthropometric measurement and laboratory study were studied. Intimal medial thickness and pulse wave velocity were estimated. Left ventricular mass index (LVMI), ejection fraction, myocardial velocity, strain and strain rate were measured by tissue Doppler imaging and strain rate imaging. RESULTS: The prevalence of MS was 7.7%. Weight, body mass index (BMI), waist circumference (WC), glucose, insulin, homeostasis model assessment of insulin resistance, triglyceride and LVMI were significantly increased in the MS group. High density lipoprotein-cholesterol (HDL-C), peak early diastolic myocardial velocity (e'), systolic myocardial velocity (s') and global longitudinal strain were significantly lower in the MS group. In univariant analysis, LVMI was significantly correlated with BMI, WC, fat %, fat mass, systolic blood pressure, alanine aminotransferase, total cholesterol (TC) and low density lipoprotein-cholesterol. e' was significantly correlated with BMI, fat %, fat mass, and HDL-C. Global circumferential strain had significant correlation with glucose and TC. Basal anterolateral strain rate was significantly correlated with weight, BMI, WC, fat %, and fat mass. CONCLUSION: LVMI, strain and strain rate are practical and accurate parameters for assessment of left ventricular function in adolescents with MS.

키워드

과제정보

연구 과제 주관 기관 : Korean Society of Echocardiography

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