Korean Journal of Radiology

  • 제16권4호
  • /
  • Pages.936-941
  • /
  • 2015
  • /
  • 1229-6929(pISSN)
  • /
  • 2005-8330(eISSN)
대한영상의학회 (The Korean Society of Radiology)
권호 표지
DOI QR코드

DOI QR Code

A Case Report: Cavitary Infarction Caused by Pulmonary Tumor Thrombotic Microangiopathy in a Patient with Pancreatic Intraductal Papillary Mucinous Neoplasm

  • Bae, Kyoungkyg (Department of Diagnostic Radiology, Ulsan University Hospital, University of Ulsan School of Medicine) ;
  • Kwon, Woon-Jung (Department of Diagnostic Radiology, Ulsan University Hospital, University of Ulsan School of Medicine) ;
  • Choi, Seong Hoon (Department of Diagnostic Radiology, Ulsan University Hospital, University of Ulsan School of Medicine) ;
  • Lee, Jong Hwa (Department of Diagnostic Radiology, Ulsan University Hospital, University of Ulsan School of Medicine) ;
  • Cha, Hee Jeong (Department of Pathology, Ulsan University Hospital, University of Ulsan School of Medicine)
  • 투고 : 2014.11.10
  • 심사 : 2015.04.05
  • 발행 : 2015.08.01
⟨ 이전 논문 다음 논문 ⟩

초록

Pulmonary tumor embolism is commonly discovered at autopsy, but is rarely suspected ante-mortem. Microangiopathy is an uncommon and distinct form of simple tumor pulmonary embolism. Here, we present a 52-year-old male with tumor thrombotic microangiopathy and pulmonary infarction, which might have originated from intraductal papillary mucinous tumor of the pancreas. Multiple wedge-shaped consolidations were found initially and aggravated with cavitation. These CT features of pulmonary infarction were pathologically confirmed to result from pulmonary tumor thrombotic microangiopathy.

키워드

참고문헌

  1. Franquet T, Gimenez A, Prats R, Rodriguez-Arias JM, Rodriguez C. Thrombotic microangiopathy of pulmonary tumors: a vascular cause of tree-in-bud pattern on CT. AJR Am J Roentgenol 2002;179:897-899 https://doi.org/10.2214/ajr.179.4.1790897
  2. Shepard JA, Moore EH, Templeton PA, McLoud TC. Pulmonary intravascular tumor emboli: dilated and beaded peripheral pulmonary arteries at CT. Radiology 1993;187:797-801 https://doi.org/10.1148/radiology.187.3.8497633
  3. Seo JB, Im JG, Goo JM, Chung MJ, Kim MY. Atypical pulmonary metastases: spectrum of radiologic findings. Radiographics 2001;21:403-417 https://doi.org/10.1148/radiographics.21.2.g01mr17403
  4. Yang Y, Choi Y, Beom SH, Kim JW, Joen YK, Kim NJ, et al. A case report of breast cancer with extensive pulmonary lymphovascular tumor emboli. J Breast Cancer 2012;15:128-132 https://doi.org/10.4048/jbc.2012.15.1.128
  5. Sancho-Chust JN, Ferreres J, Pineda J, Molla MA, Giner F, Juan M, et al. Pulmonary tumor embolism as an initial manifestation of pancreatic adenocarcinoma. Respir Care 2009;54:1732-1735
  6. Greaves SM, Hart EM, Brown K, Young DA, Batra P, Aberle DR. Pulmonary thromboembolism: spectrum of findings on CT. AJR Am J Roentgenol 1995;165:1359-1363 https://doi.org/10.2214/ajr.165.6.7484563
  7. Redline S, Tomashefski JF Jr, Altose MD. Cavitating lung infarction after bland pulmonary thromboembolism in patients with the adult respiratory distress syndrome. Thorax 1985;40:915-919 https://doi.org/10.1136/thx.40.12.915
  8. Babu RV, Romero A, Sharma G. A 39-year-old man with epigastric pain, intermittent chest pain, and progressive dyspnea. Chest 2007;132:2012-2015 https://doi.org/10.1378/chest.07-0878
  9. Pinckard JK, Wick MR. Tumor-related thrombotic pulmonary microangiopathy: review of pathologic findings and pathophysiologic mechanisms. Ann Diagn Pathol 2000;4:154-157 https://doi.org/10.1016/S1092-9134(00)90038-8
  10. Chinen K, Kazumoto T, Ohkura Y, Matsubara O, Tsuchiya E. Pulmonary tumor thrombotic microangiopathy caused by a gastric carcinoma expressing vascular endothelial growth factor and tissue factor. Pathol Int 2005;55:27-31 https://doi.org/10.1111/j.1440-1827.2005.01783.x
  11. Morgenthaler TI, Ryu JH, Utz JP. Cavitary pulmonary infarct in immunocompromised hosts. Mayo Clin Proc 1995;70:66-68 https://doi.org/10.1016/S0025-6196(11)64668-5
  12. Harris H, Barraclough R, Davies C, Armstrong I, Kiely DG, van Beek E Jr. Cavitating lung lesions in chronic thromboembolic pulmonary hypertension. J Radiol Case Rep 2008;2:11-21 https://doi.org/10.1186/1752-1947-2-11

피인용 문헌

  1. Pulmonary tumor thrombotic microangiopathy: a systematic review vol.9, pp.2, 2015, https://doi.org/10.1177/2045894019851000
  2. An autopsy case of a patient with systemic sclerosis who developed marked pulmonary hypertension because of pulmonary tumor thrombotic microangiopathy caused by gastric carcinoma vol.4, pp.1, 2020, https://doi.org/10.1080/24725625.2019.1690767