Korean Journal of Radiology

The Korean Society of Radiology (대한영상의학회)
권호 표지
DOI QR코드

DOI QR Code

Development of Coronary Vasospasm during Adenosine-Stress Myocardial Perfusion CT Imaging

  • Nam, Jeong Gu (Department of Radiology, Ulsan University Hospital, University of Ulsan College of Medicine) ;
  • Choi, Seong Hoon (Department of Radiology, Ulsan University Hospital, University of Ulsan College of Medicine) ;
  • Kang, Byeong Seong (Department of Radiology, Ulsan University Hospital, University of Ulsan College of Medicine) ;
  • Bang, Min Seo (Department of Radiology, Ulsan University Hospital, University of Ulsan College of Medicine) ;
  • Kwon, Woon Jeong (Department of Radiology, Ulsan University Hospital, University of Ulsan College of Medicine)
  • Received : 2014.09.11
  • Accepted : 2015.01.19
  • Published : 2015.06.01
⟨ Previous Next ⟩

Abstract

Adenosine is a short-acting coronary vasodilator, and it is widely used during pharmacological stress myocardial perfusion imaging. It has a well-established safety profile, and most of its side effects are known to be mild and transient. Until now, coronary vasospasm has been rarely reported as a side effect of adenosine during or after adenosine stress test. This study reports a case of coronary vasospasm which was documented on stress myocardial perfusion CT imaging during adenosine stress test.

Keywords

References

  1. Anagnostopoulos C, Harbinson M, Kelion A, Kundley K, Loong CY, Notghi A, et al. Procedure guidelines for radionuclide myocardial perfusion imaging. Heart 2004;90 Suppl 1:i1-i10 https://doi.org/10.1136/heart.90.suppl_1.i1
  2. Weissman G, Scandrett RM, Howes CJ, Russell RR 3rd. Coronary vasospasm during an adenosine stress test. J Nucl Cardiol 2004;11:747-750 https://doi.org/10.1016/j.nuclcard.2004.09.004
  3. Faganello G, Belham M. Coronary vasospasm during an adenosine stress test. Int J Cardiol 2006;113:E84-E86 https://doi.org/10.1016/j.ijcard.2006.04.074
  4. Golzar J, Mustafa SJ, Movahed A. Chest pain and ST-segment elevation 3 minutes after completion of adenosine pharmacologic stress testing. J Nucl Cardiol 2004;11:744-746 https://doi.org/10.1016/j.nuclcard.2004.08.003
  5. Rosenberg T, Perdrisot R. Coronary spasm after an adenosine stress test: an adverse effect of a vasodilator. Acta Cardiol 2008;63:401-404 https://doi.org/10.2143/AC.63.3.1020320
  6. Nakayama M, Morishima T, Chikamori T, Aiga M, Takazawa K, Yamashina A. Coronary arterial spasm during adenosine myocardial perfusion imaging. J Cardiol 2009;53:288-292 https://doi.org/10.1016/j.jjcc.2008.07.017
  7. Han PP, Tian YQ, Wei HX, Wang Q, He ZX. Coronary spasm after completion of adenosine pharmacologic stress test. Ann Nucl Med 2011;25:580-585 https://doi.org/10.1007/s12149-011-0493-z
  8. Cerqueira MD, Verani MS, Schwaiger M, Heo J, Iskandrian AS. Safety profile of adenosine stress perfusion imaging: results from the Adenoscan Multicenter Trial Registry. J Am Coll Cardiol 1994;23:384-389 https://doi.org/10.1016/0735-1097(94)90424-3
  9. Baskot B, Rafajlovski S, Ristic-Angelkov A, Obradovic S, Gligic B, Orozovic V, et al. [Study of efficacy and safety of pharmacological stress tests in nuclear cardiology]. Vojnosanit Pregl 2009;66:193-198 https://doi.org/10.2298/VSP0903193B
  10. Sato A, Terata K, Miura H, Toyama K, Loberiza FR Jr, Hatoum OA, et al. Mechanism of vasodilation to adenosine in coronary arterioles from patients with heart disease. Am J Physiol Heart Circ Physiol 2005;288:H1633-H1640 https://doi.org/10.1152/ajpheart.00575.2004
  11. Miyagawa M, Kumano S, Sekiya M, Watanabe K, Akutzu H, Imachi T, et al. Thallium-201 myocardial tomography with intravenous infusion of adenosine triphosphate in diagnosis of coronary artery disease. J Am Coll Cardiol 1995;26:1196-1201 https://doi.org/10.1016/0735-1097(95)00304-5
  12. Feuchtner G, Goetti R, Plass A, Wieser M, Scheffel H, Wyss C, et al. Adenosine stress high-pitch 128-slice dual-source myocardial computed tomography perfusion for imaging of reversible myocardial ischemia: comparison with magnetic resonance imaging. Circ Cardiovasc Imaging 2011;4:540-549 https://doi.org/10.1161/CIRCIMAGING.110.961250
  13. Ansari HR, Teng B, Nadeem A, Roush KP, Martin KH, Schnermann J, et al. A(1) adenosine receptor-mediated PKC and p42/p44 MAPK signaling in mouse coronary artery smooth muscle cells. Am J Physiol Heart Circ Physiol 2009;297:H1032-H1039 https://doi.org/10.1152/ajpheart.00374.2009
  14. Hung MJ, Hu P, Hung MY. Coronary artery spasm: review and update. Int J Med Sci 2014;11:1161-1171 https://doi.org/10.7150/ijms.9623

Cited by

  1. Coronary artery calcium scores and cardiovascular risk factors in 31,545 asymptomatic Korean adults vol.32, pp.1, 2015, https://doi.org/10.1007/s10554-016-0892-2
  2. Coronary arterial spasm detected by coronary computed tomography angiography and confirmed by intravascular ultrasound vol.13, pp.1, 2018, https://doi.org/10.1016/j.radcr.2017.09.002
  3. Coronary artery spasm following dobutamine stress echocardiogram vol.13, pp.8, 2015, https://doi.org/10.1136/bcr-2020-235206