Korean Journal of Radiology

The Korean Society of Radiology (대한영상의학회)
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Imaging Surveillance of Patients with Breast Cancer after Primary Treatment: Current Recommendations

  • Yoon, Jung Hyun (Department of Radiology, Severance Hospital, Research Institute of Radiological Science, Yonsei University College of Medicine) ;
  • Kim, Min Jung (Department of Radiology, Severance Hospital, Research Institute of Radiological Science, Yonsei University College of Medicine) ;
  • Kim, Eun-Kyung (Department of Radiology, Severance Hospital, Research Institute of Radiological Science, Yonsei University College of Medicine) ;
  • Moon, Hee Jung (Department of Radiology, Severance Hospital, Research Institute of Radiological Science, Yonsei University College of Medicine)
  • Received : 2014.03.08
  • Accepted : 2014.11.24
  • Published : 2015.04.01
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Abstract

Women who have been treated for breast cancer are at risk for second breast cancers, such as ipsilateral recurrence or contralateral metachronous breast cancer. As the number of breast cancer survivors increases, interest in patient management and surveillance after treatment has also increased. However, post-treatment surveillance programs for patients with breast cancer have not been firmly established. In this review, we focus on the imaging modalities that have been used in post-treatment surveillance for patients with breast cancer, such as mammography, ultrasonography, magnetic resonance imaging, and positron emission tomography, the effectiveness of each modality for detecting recurrence, and how they can be applied to manage patients.

Keywords

References

  1. Senkus E, Kyriakides S, Penault-Llorca F, Poortmans P, Thompson A, Zackrisson S, et al. Primary breast cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol 2013;24 Suppl 6:vi7-vi23
  2. Houssami N, Ciatto S, Martinelli F, Bonardi R, Duffy SW. Early detection of second breast cancers improves prognosis in breast cancer survivors. Ann Oncol 2009;20:1505-1510 https://doi.org/10.1093/annonc/mdp037
  3. Jung KW, Won YJ, Kong HJ, Oh CM, Lee DH, Lee JS. Cancer statistics in Korea: incidence, mortality, survival, and prevalence in 2011. Cancer Res Treat 2014;46:109-123 https://doi.org/10.4143/crt.2014.46.2.109
  4. Houssami N, Ciatto S. Mammographic surveillance in women with a personal history of breast cancer: how accurate? How effective? Breast 2010;19:439-445 https://doi.org/10.1016/j.breast.2010.05.010
  5. Kim MJ, Kim EK, Kwak JY, Park BW, Kim SI, Sohn J, et al. Role of sonography in the detection of contralateral metachronous breast cancer in an Asian population. AJR Am J Roentgenol 2008;190:476-480 https://doi.org/10.2214/AJR.07.2683
  6. Grunfeld E, Noorani H, McGahan L, Paszat L, Coyle D, van Walraven C, et al. Surveillance mammography after treatment of primary breast cancer: a systematic review. Breast 2002;11:228-235 https://doi.org/10.1054/brst.2001.0404
  7. Karam AK. Breast cancer posttreatment surveillance: diagnosis and management of recurrent disease. Clin Obstet Gynecol 2011;54:157-163 https://doi.org/10.1097/GRF.0b013e318208393b
  8. Rissanen TJ, Makarainen HP, Mattila SI, Lindholm EL, Heikkinen MI, Kiviniemi HO. Breast cancer recurrence after mastectomy: diagnosis with mammography and US. Radiology 1993;188:463-467 https://doi.org/10.1148/radiology.188.2.8327698
  9. Voogd AC, van Tienhoven G, Peterse HL, Crommelin MA, Rutgers EJ, van de Velde CJ, et al. Local recurrence after breast conservation therapy for early stage breast carcinoma: detection, treatment, and outcome in 266 patients. Dutch Study Group on Local Recurrence after Breast Conservation (BORST). Cancer 1999;85:437-446 https://doi.org/10.1002/(SICI)1097-0142(19990115)85:2<437::AID-CNCR23>3.0.CO;2-1
  10. Kemperman H, Borger J, Hart A, Peterse H, Bartelink H, van Dongen J. Prognostic factors for survival after breast conserving therapy for stage I and II breast cancer. The role of local recurrence. Eur J Cancer 1995;31A:690-698
  11. Khatcheressian JL, Hurley P, Bantug E, Esserman LJ, Grunfeld E, Halberg F, et al. Breast cancer follow-up and management after primary treatment: American Society of Clinical Oncology clinical practice guideline update. J Clin Oncol 2013;31:961-965 https://doi.org/10.1200/JCO.2012.45.9859
  12. Ciatto S, Miccinesi G, Zappa M. Prognostic impact of the early detection of metachronous contralateral breast cancer. Eur J Cancer 2004;40:1496-1501 https://doi.org/10.1016/j.ejca.2004.03.010
  13. Lu W, Schaapveld M, Jansen L, Bagherzadegan E, Sahinovic MM, Baas PC, et al. The value of surveillance mammography of the contralateral breast in patients with a history of breast cancer. Eur J Cancer 2009;45:3000-3007 https://doi.org/10.1016/j.ejca.2009.08.007
  14. Robertson C, Ragupathy SK, Boachie C, Fraser C, Heys SD, Maclennan G, et al. Surveillance mammography for detecting ipsilateral breast tumour recurrence and metachronous contralateral breast cancer: a systematic review. Eur Radiol 2011;21:2484-2491 https://doi.org/10.1007/s00330-011-2226-z
  15. Rojas MP, Telaro E, Russo A, Moschetti I, Coe L, Fossati R, et al. Follow-up strategies for women treated for early breast cancer. Cochrane Database Syst Rev 2005:CD001768
  16. Hayes DF. Clinical practice. Follow-up of patients with early breast cancer. N Engl J Med 2007;356:2505-2513 https://doi.org/10.1056/NEJMcp067260
  17. Association of Breast Surgery @ BASO, Royal College of Surgeons of England. Guidelines for the management of symptomatic breast disease. Eur J Surg Oncol 2005;31 Suppl 1:1-21
  18. Gabe R, Duffy SW. Evaluation of service screening mammography in practice: the impact on breast cancer mortality. Ann Oncol 2005;16 Suppl 2:ii153-ii162 https://doi.org/10.1093/annonc/mdi718
  19. Roder D, Houssami N, Farshid G, Gill G, Luke C, Downey P, et al. Population screening and intensity of screening are associated with reduced breast cancer mortality: evidence of efficacy of mammography screening in Australia. Breast Cancer Res Treat 2008;108:409-416 https://doi.org/10.1007/s10549-007-9609-5
  20. Saslow D, Boetes C, Burke W, Harms S, Leach MO, Lehman CD, et al. American Cancer Society guidelines for breast screening with MRI as an adjunct to mammography. CA Cancer J Clin 2007;57:75-89 https://doi.org/10.3322/canjclin.57.2.75
  21. Montgomery DA, Krupa K, Jack WJ, Kerr GR, Kunkler IH, Thomas J, et al. Changing pattern of the detection of locoregional relapse in breast cancer: the Edinburgh experience. Br J Cancer 2007;96:1802-1807 https://doi.org/10.1038/sj.bjc.6603815
  22. Paszat L, Sutradhar R, Grunfeld E, Gainford C, Benk V, Bondy S, et al. Outcomes of surveillance mammography after treatment of primary breast cancer: a population-based case series. Breast Cancer Res Treat 2009;114:169-178 https://doi.org/10.1007/s10549-008-9986-4
  23. Lu WL, Jansen L, Post WJ, Bonnema J, Van de Velde JC, De Bock GH. Impact on survival of early detection of isolated breast recurrences after the primary treatment for breast cancer: a meta-analysis. Breast Cancer Res Treat 2009;114:403-412 https://doi.org/10.1007/s10549-008-0023-4
  24. Obdeijn IM, Winter-Warnars GA, Mann RM, Hooning MJ, Hunink MG, Tilanus-Linthorst MM. Should we screen BRCA1 mutation carriers only with MRI? A multicenter study. Breast Cancer Res Treat 2014;144:577-582 https://doi.org/10.1007/s10549-014-2888-8
  25. Berg WA, Zhang Z, Lehrer D, Jong RA, Pisano ED, Barr RG, et al. Detection of breast cancer with addition of annual screening ultrasound or a single screening MRI to mammography in women with elevated breast cancer risk. JAMA 2012;307:1394-1404 https://doi.org/10.1001/jama.2012.388
  26. Dershaw DD, Lee CH, Morris EA. Mammographic surveillance after breast conservation therapy. Radiology 2013;266:685 https://doi.org/10.1148/radiol.12121630
  27. Berg WA, Blume JD, Cormack JB, Mendelson EB, Lehrer D, Bohm-Velez M, et al. Combined screening with ultrasound and mammography vs mammography alone in women at elevated risk of breast cancer. JAMA 2008;299:2151-2163 https://doi.org/10.1001/jama.299.18.2151
  28. Kim MJ, Kim EK, Kwak JY, Park BW, Kim SI, Oh KK. Bilateral synchronous breast cancer in an Asian population: mammographic and sonographic characteristics, detection methods, and staging. AJR Am J Roentgenol 2008;190:208-213 https://doi.org/10.2214/AJR.07.2714
  29. Moon WK, Noh DY, Im JG. Multifocal, multicentric, and contralateral breast cancers: bilateral whole-breast US in the preoperative evaluation of patients. Radiology 2002;224:569-576 https://doi.org/10.1148/radiol.2242011215
  30. Balu-Maestro C, Bruneton JN, Geoffray A, Chauvel C, Rogopoulos A, Bittman O. Ultrasonographic posttreatment follow-up of breast cancer patients. J Ultrasound Med 1991;10:1-7 https://doi.org/10.7863/jum.1991.10.1.1
  31. Belli P, Costantini M, Romani M, Marano P, Pastore G. Magnetic resonance imaging in breast cancer recurrence. Breast Cancer Res Treat 2002;73:223-235 https://doi.org/10.1023/A:1015868406986
  32. Kim SM, Park JM. Normal and abnormal US findings at the mastectomy site. Radiographics 2004;24:357-365 https://doi.org/10.1148/rg.242035072
  33. Kim MJ, Kim EK, Kwak JY, Park BW, Kim SI, Sohn J, et al. Sonographic surveillance for the detection of contralateral metachronous breast cancer in an Asian population. AJR Am J Roentgenol 2009;192:221-228 https://doi.org/10.2214/AJR.07.4048
  34. Shin JH, Han BK, Choe YH, Nam SJ, Park W, Im YH. Ultrasonographic detection of occult cancer in patients after surgical therapy for breast cancer. J Ultrasound Med 2005;24:643-649 https://doi.org/10.7863/jum.2005.24.5.643
  35. Eubank WB, Mankoff DA, Vesselle HJ, Eary JF, Schubert EK, Dunnwald LK, et al. Detection of locoregional and distant recurrences in breast cancer patients by using FDG PET. Radiographics 2002;22:5-17 https://doi.org/10.1148/radiographics.22.1.g02ja055
  36. Katz A, Strom EA, Buchholz TA, Thames HD, Smith CD, Jhingran A, et al. Locoregional recurrence patterns after mastectomy and doxorubicin-based chemotherapy: implications for postoperative irradiation. J Clin Oncol 2000;18:2817-2827 https://doi.org/10.1200/JCO.2000.18.15.2817
  37. Kanso H, Kazzi H, Menassa-Moussa L, Abi Khalil S, Ghosn M, Chahine G, et al. [Value of US imaging following mastectomy]. J Radiol 2008;89(9 Pt 1):1077-1080 https://doi.org/10.1016/S0221-0363(08)73911-8
  38. Kim SJ, Moon WK, Cho N, Chang JM. The detection of recurrent breast cancer in patients with a history of breast cancer surgery: comparison of clinical breast examination, mammography and ultrasonography. Acta Radiol 2011;52:15-20 https://doi.org/10.1258/ar.2010.100261
  39. Lee JH, Kim EK, Oh JY, Kwon HC, Kim SH, Kim DC, et al. US screening for detection of nonpalpable locoregional recurrence after mastectomy. Eur J Radiol 2013;82:485-489 https://doi.org/10.1016/j.ejrad.2012.10.007
  40. Suh YJ, Kim MJ, Kim EK, Moon HJ, Kim SI, Park BW. Value of ultrasound for postoperative surveillance of asian patients with history of breast cancer surgery: a single-center study. Ann Surg Oncol 2013;20:3461-3468 https://doi.org/10.1245/s10434-013-3020-8
  41. Kim HJ, Kwak JY, Choi JW, Bae JH, Shin KM, Lee HJ, et al. Impact of US surveillance on detection of clinically occult locoregional recurrence after mastectomy for breast cancer. Ann Surg Oncol 2010;17:2670-2676 https://doi.org/10.1245/s10434-010-1087-z
  42. Moon HJ, Kim MJ, Kim EK, Park BW, Youk JH, Kwak JY, et al. US surveillance of regional lymph node recurrence after breast cancer surgery. Radiology 2009;252:673-681 https://doi.org/10.1148/radiol.2523081977
  43. Schmoor C, Sauerbrei W, Bastert G, Schumacher M. Role of isolated locoregional recurrence of breast cancer: results of four prospective studies. J Clin Oncol 2000;18:1696-1708 https://doi.org/10.1200/JCO.2000.18.8.1696
  44. Boetes C, Veltman J. Screening women at increased risk with MRI. Cancer Imaging 2005;5 Spec No A:S10-S15 https://doi.org/10.1102/1470-7330.2005.0040
  45. Echevarria JJ, Martin M, Saiz A, Imaz I, Fernandez-Ruanova B, Martin D, et al. Overall breast density in MR mammography: diagnostic and therapeutic implications in breast cancer. J Comput Assist Tomogr 2006;30:140-147 https://doi.org/10.1097/01.rct.0000191684.51215.9c
  46. Lee SG, Orel SG, Woo IJ, Cruz-Jove E, Putt ME, Solin LJ, et al. MR imaging screening of the contralateral breast in patients with newly diagnosed breast cancer: preliminary results. Radiology 2003;226:773-778 https://doi.org/10.1148/radiol.2263020041
  47. Mainiero MB, Lourenco A, Mahoney MC, Newell MS, Bailey L, Barke LD, et al. ACR Appropriateness Criteria Breast Cancer Screening. J Am Coll Radiol 2013;10:11-14 https://doi.org/10.1016/j.jacr.2012.09.036
  48. Lee CH, Dershaw DD, Kopans D, Evans P, Monsees B, Monticciolo D, et al. Breast cancer screening with imaging: recommendations from the Society of Breast Imaging and the ACR on the use of mammography, breast MRI, breast ultrasound, and other technologies for the detection of clinically occult breast cancer. J Am Coll Radiol 2010;7:18-27 https://doi.org/10.1016/j.jacr.2009.09.022
  49. Brennan S, Liberman L, Dershaw DD, Morris E. Breast MRI screening of women with a personal history of breast cancer. AJR Am J Roentgenol 2010;195:510-516 https://doi.org/10.2214/AJR.09.3573
  50. Viehweg P, Heinig A, Lampe D, Buchmann J, Heywang-Kobrunner SH. Retrospective analysis for evaluation of the value of contrast-enhanced MRI in patients treated with breast conservative therapy. MAGMA 1998;7:141-152 https://doi.org/10.1007/BF02591331
  51. Morris EA, Liberman L, Ballon DJ, Robson M, Abramson AF, Heerdt A, et al. MRI of occult breast carcinoma in a high-risk population. AJR Am J Roentgenol 2003;181:619-626 https://doi.org/10.2214/ajr.181.3.1810619
  52. Quinn EM, Coveney AP, Redmond HP. Use of magnetic resonance imaging in detection of breast cancer recurrence: a systematic review. Ann Surg Oncol 2012;19:3035-3041 https://doi.org/10.1245/s10434-012-2341-3
  53. Groheux D, Espie M, Giacchetti S, Hindie E. Performance of FDG PET/CT in the clinical management of breast cancer. Radiology 2013;266:388-405 https://doi.org/10.1148/radiol.12110853
  54. Pan L, Han Y, Sun X, Liu J, Gang H. FDG-PET and other imaging modalities for the evaluation of breast cancer recurrence and metastases: a meta-analysis. J Cancer Res Clin Oncol 2010;136:1007-1022 https://doi.org/10.1007/s00432-009-0746-6
  55. Aukema TS, Rutgers EJ, Vogel WV, Teertstra HJ, Oldenburg HS, Vrancken Peeters MT, et al. The role of FDG PET/CT in patients with locoregional breast cancer recurrence: a comparison to conventional imaging techniques. Eur J Surg Oncol 2010;36:387-392 https://doi.org/10.1016/j.ejso.2009.11.009
  56. Parmar AD, Sheffield KM, Vargas GM, Han Y, Chao C, Riall TS. Quality of post-treatment surveillance of early stage breast cancer in Texas. Surgery 2013;154:214-225 https://doi.org/10.1016/j.surg.2013.04.004
  57. Rosselli Del Turco M, Palli D, Cariddi A, Ciatto S, Pacini P, Distante V. Intensive diagnostic follow-up after treatment of primary breast cancer. A randomized trial. National Research Council Project on Breast Cancer follow-up. JAMA 1994;271:1593-1597 https://doi.org/10.1001/jama.1994.03510440053032
  58. Drew PJ, Kerin MJ, Turnbull LW, Imrie M, Carleton PJ, Fox JN, et al. Routine screening for local recurrence following breast-conserving therapy for cancer with dynamic contrast-enhanced magnetic resonance imaging of the breast. Ann Surg Oncol 1998;5:265-270 https://doi.org/10.1007/BF02303784

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