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Relationship between duration of hospital-acquired acute kidney injury and mortality: a prospective observational study

  • Yoo, Jinyoung (Division of Nephrology, Soonchunhyang University Hospital) ;
  • Lee, Ji Sung (Biostatistical Consulting Unit, Soonchunhyang University Hospital) ;
  • Lee, Jiyeon (Division of Nephrology, Soonchunhyang University Hospital) ;
  • Jeon, Jin Seok (Division of Nephrology, Soonchunhyang University Hospital) ;
  • Noh, Hyunjin (Division of Nephrology, Soonchunhyang University Hospital) ;
  • Han, Dong Cheol (Division of Nephrology, Soonchunhyang University Hospital) ;
  • Kwon, Soon Hyo (Division of Nephrology, Soonchunhyang University Hospital)
  • 투고 : 2014.04.29
  • 심사 : 2014.06.30
  • 발행 : 2015.03.01

초록

Background/Aims: New definitions of acute kidney injury (AKI) have recently emerged. Some studies have suggested that duration of AKI is an additional predictive parameter for mortality. Here, we evaluated whether AKI duration was predictive of long-term mortality in patients with hospital-acquired acute kidney injury (HAAKI). Methods: We prospectively enrolled patients who developed HAAKI at an urban university hospital, from September 2007 to August 2008 and followed them until December 2011. Patients were divided into two groups by duration of the AKI (1 to 5 days vs. ${\geq}6days$), and long-term mortality was compared. Results: HAAKI developed in 1.2% of patients during the enrollment period. The median follow-up period was 240 days (interquartile range, 53 to 1,428). In 42.3% of patients (n = 52), the AKI lasted 1 to 5 days, while it lasted ${\geq}6days$ in 57.7% (n = 71). Survival analysis showed that a longer duration of AKI increased the risk of death. Long-term survival was significantly different in the two groups. Conclusions: The duration of AKI influenced mortality rates in hospitalized patients. Thus, AKI duration is a parameter affecting mortality in HAAKI.

키워드

과제정보

연구 과제 주관 기관 : Soonchunhyang University

참고문헌

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피인용 문헌

  1. Clinical evaluation of acute kidney injury in Al-Zahraa University Hospital, Cairo, Egypt vol.29, pp.None, 2017, https://doi.org/10.4103/ejim.ejim_3_17
  2. A decrease in serum creatinine after ICU admission is associated with increased mortality vol.12, pp.8, 2017, https://doi.org/10.1371/journal.pone.0183156
  3. The prognostic importance of duration of AKI: a systematic review and meta-analysis vol.19, pp.1, 2015, https://doi.org/10.1186/s12882-018-0876-7
  4. Mortality and predictors of acute kidney injury in adults: a hospital-based prospective observational study vol.11, pp.1, 2021, https://doi.org/10.1038/s41598-021-94946-3