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일개 대학병원의 임상검체에서 분리된 6년간의 효모균 분포에 관한 연구

Study on Distribution of Yeast Isolated from Clinical Specimens for Six Years in a University-affiliated Hospital

  • 마판곤 (대구보건대학교 임상병리과) ;
  • 김선주 (경상대학교 의과대학 진단검사의학교실) ;
  • 서충원 (송호대학교 임상병리과) ;
  • 유영빈 (건양대학교 임상병리학과) ;
  • 김영권 (건양대학교 임상병리학과)
  • Ma, Pan-Gon (Dept. of Biomedical Laboratory Science, Daegu Health Science College) ;
  • Kim, Sun-Joo (Dept. of Laboratory Medicine, Gyeongsang National University School of Medicine) ;
  • Seo, Choong-Won (Dept. of Biomedical Laboratory Science, Songho College) ;
  • Yu, Young-Bin (Dept. of Biomedical Laboratory Science, Konyang University) ;
  • Kim, Young-Kwon (Dept. of Biomedical Laboratory Science, Konyang University)
  • 투고 : 2015.07.12
  • 심사 : 2015.09.20
  • 발행 : 2015.09.28

초록

본 연구는 한 대학병원에서 6 년간 (2006-2011) 다양한 임상 검체에서 분리된 진균의 빈도를 조사하여 임상검체에서 진균의 종류에 따른 연관성을 파악하여 이와 관련된 환자 관리에 필요한 정보를 제공하기 위함이다. 경상남도의 단일 대학병원 진단검사의학과 미생물검사실로 의뢰된 검체 163,530건을 대상으로 하였고 배양에서 양성으로 판정된 진균 5,378주(3.3%)에 대하여 환자의 일반적인 특징과 성별, 연령, 검체 종류를 분석하였다. 균주별 분리빈도는 Candida albicans가 41.9%로 가장 많았고, Candida glabrata (15.5%), Candida tropicalis (14.6%)가 그 다음 순서로 분리되었다. 분리건수는 2006년 526건에서 2011년이 1,145건으로 2배이상 증가하였다. 연령별로는 60대(27.0%)와 70대(26.5%)에서 가장 흔히 분리되었다. 검체별로는 소변이 44.8%로 가장 많았다. 성별에 따른 분리는 남성이 52.4%로 여성 47.6%보다 약간 높았다. 추후 전국적인 분포도를 연구하고, 항진균 융복합 약제 감수성을 분석한다면 더 유익한 자료를 제공할 것으로 사료된다.

We investigated the prevalence of fungi isolated from a university-affiliated hospital during 6 years (2006-2011) to provide relevent information for the patient management. The general characteristics of the clinical isolates and gender, age, and type of specimens were analyzed. Among a total of 163,530 requested samples to culture for the Laboratory of Clinical Microbiology, Department of Laboratory Medicine, Gyeongsang National University Hospital in the Republic of Korea, 5,387 (3.3%) showd positive results for fungi. The most prevalent isolates were Candida albicans 41.9%, Candida glabrata 15.5%, and Candida tropicalis 14.6%. Total isolates of fungi increased from 526 in 2006 to 1,145 in 2011. They were most commonly isolated from sixties (27.0%) and seventies (26.5%). The most common clinical specimen was urine (44.8%). Males (52.4%) were slightly more than females (47.6%). In the future, a nationwide survey and additional antifungal convergence drugs susceptibility results will provide more useful information.

키워드

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