Asian Pacific Journal of Cancer Prevention

Asian Pacific Journal of Cancer Prevention (아시아태평양암예방학회)
권호 표지
DOI QR코드

DOI QR Code

Accuracy of Endoscopic Ultrasonography for Determination of Tumor Invasion Depth in Gastric Cancer

  • Razavi, Seyed Mohsen (Hematology and Oncology Department, Iran University of Medical Sciences) ;
  • Khodadost, Mahmoud (Department of Epidemiology, Faculty of Public health, Shahid Beheshti University of Medical Sciences) ;
  • Sohrabi, Masoudreza (Gastrointestinal and Liver Diseases Research Centre, Firoozgar Hospital, Iran University of Medical Sciences) ;
  • Keshavarzi, Azam (Hematology and Oncology Department, Iran University of Medical Sciences) ;
  • Zamani, Farhad (Gastrointestinal and Liver Diseases Research Centre, Firoozgar Hospital, Iran University of Medical Sciences) ;
  • Rakhshani, Naser (Gastrointestinal and Liver Diseases Research Centre, Firoozgar Hospital, Iran University of Medical Sciences) ;
  • Ameli, Mitra (Gastrointestinal and Liver Diseases Research Centre, Firoozgar Hospital, Iran University of Medical Sciences) ;
  • Sadeghi, Reza (Gastrointestinal and Liver Diseases Research Centre, Firoozgar Hospital, Iran University of Medical Sciences) ;
  • Hatami, Khadijeh (Gastrointestinal and Liver Diseases Research Centre, Firoozgar Hospital, Iran University of Medical Sciences) ;
  • Ajdarkosh, Hossein (Gastrointestinal and Liver Diseases Research Centre, Firoozgar Hospital, Iran University of Medical Sciences) ;
  • Golmahi, Zeynab (Aging Research Center, Sabzevar University of Medical Sciences and Health Services) ;
  • Ranjbaran, Mehdi (Department of Epidemiology, Faculty of Health, Arak University of Medical Sciences)
  • Published : 2015.04.29
Download PDF
⟨ Previous Next ⟩

Abstract

Background: Gastric cancer (GC) is one the common lethal cancers in Iran. Detection of GC in the early stages would assesses to improve the survival of patients. In this study, we attempt to evaluate the accuracy of EUS in detection depth of invasion of GC among Iranian Patients. Materials and Methods: This study is a retrospective study of patients with pathologically confirmed GC. They underwent EUS before initiating the treatment. The accuracy of EUS and agreement between the two methods was evaluated by comparing pre treatment EUS finding with post operative histopathological results. Results: The overall accuracy of EUS for T and N staging was 67.9% and 75.47, respectively. Underestimation and overestimation was seen in 22 (14.2%) and 40 (25.6%) respectively. The EUS was more accurate in large tumors and the tumors located in the middle and lower parts of the stomach. The EUS was more sensitive in T3 staging. The values of weighted Kappa from the T and N staging were 0.53 and 0.66, respectively. Conclusions: EUS is a useful modality for evaluating the depth of invasion of GC. The accuracy of EUS was higher if the tumor was located in the lower parts of the stomach and the size of the tumor was more than 3 cm. Therefore, judgments made upon other criteria evaluated in this study need to be reconsidered.

Keywords

References

  1. Aghaei A, Ahmadi-Jouibari T, Baiki O, et al (2013). Estimation of the gastric cancer incidence in Tehran by two-source capture-recapture. Asian Pac J Cancer Prev, 14, 673-7. https://doi.org/10.7314/APJCP.2013.14.2.673
  2. Bohle W, Scheidig A, Zoller WG (2011). Endosonographic tumor staging for treatment decision in resectable gastric cancer. J Gastrointestin Liver Dis, 20, 135-9.
  3. Botet JF, Lightdale C (1992). Endoscopic ultrasonography of the upper gastrointestinal tract. Radiol Clin North Am, 30, 1067-83.
  4. Botet JF, Lightdale C (1995). Endoscopic ultrasonography of the gastrointestinal tract. Gastroenterol Clin North Am, 24, 385-412.
  5. De Angelis C, Pellicano R, Manfre SF, et al (2013). Endoscopic ultrasound in the 2013 preoperative evaluation of gastric cancer. Minerva Gastroenterol Dietol, 59, 1-12.
  6. Ganpathi IS, So JB, Ho KY (2006). Endoscopic ultrasonography for gastric cancer: does it influence treatment? Surg Endosc, 20, 559-62. https://doi.org/10.1007/s00464-005-0309-0
  7. Garlipp B, Schwalenberg J, Adolf D, et al (2011). Epidemiology, surgical management and early postoperative outcome in a cohort of gastric cancer patients of a tertiary referral center in relation to multi-center quality assurance studies. Pol Przegl Chir, 83, 123-34.
  8. Goh LY, Leow AH, Goh KL (2014). Observations on the epidemiology of gastrointestinal and liver cancers in the Asian-Pacific region. J Dig Dis, 15, 463-8. https://doi.org/10.1111/1751-2980.12164
  9. Haidari M, Nikbakht MR, Pasdar Y, et al (2012). Trend analysis of gastric cancer incidence in Iran and its six geographical areas during 2000-2005. Asian Pac J Cancer Prev, 13, 3335-41. https://doi.org/10.7314/APJCP.2012.13.7.3335
  10. Japanese Gastric Cancer Association (1998). Japanese classification of gastric carcinoma - 2nd English edition. Gastric Cancer, 1, 10-24. https://doi.org/10.1007/PL00011681
  11. Jurgensen C, Brand J, Nothnagel M, et al (2013). Prognostic relevance of gastric cancer staging by endoscopic ultrasound. Surg Endosc, 27, 1124-9. https://doi.org/10.1007/s00464-012-2558-z
  12. Karimi P, Islami F, Anandasabapathy S, et al (2014). Gastric cancer: descriptive epidemiology, risk factors, screening, and prevention. Cancer Epidemiol Biomarkers Prev, 23, 700-13. https://doi.org/10.1158/1055-9965.EPI-13-1057
  13. Kikuchi D, Iizuka T, Hoteya S, et al (2011). Usefulness of endoscopic ultrasound for the prediction of intraoperative bleeding of endoscopic submucosal dissection for gastric neoplasms. J Gastroenterol Hepatol, 26, 68-72.
  14. Kim J, Ryu JK, Park JM, et al (2014). Clinical factors associated with accuracy of EUS-FNA for pancreatic or peripancreatic solid mass without on-site cytopathologists. J Gastroenterol Hepatol, 29, 887-92. https://doi.org/10.1111/jgh.12497
  15. Kim MK (2012). Endoscopic ultrasound in gastroenteropancreatic neuroendocrine tumors. Gut Liver, 6, 405-10. https://doi.org/10.5009/gnl.2012.6.4.405
  16. Koessler T, Roth A, Cacheux W (2014). Early gastric cancer:epidemiology, diagnostic and management. Rev Med Suisse, 10, 1118-22 (in German).
  17. Kolahdoozan S, Sadjadi A, Radmard AR, et al (2010). Five common cancers in Iran. Arch Iran Med, 13, 143-6.
  18. Kutup A, Vashist YK, Groth S, et al (2012). Endoscopic ultrasound staging in gastric cancer: does it help management decisions in the era of neoadjuvant treatment? Endoscopy, 44, 572-6. https://doi.org/10.1055/s-0032-1308950
  19. Lee HH, Lim CH, Park JM, et al (2012). Low accuracy of endoscopic ultrasonography for detailed T staging in gastric cancer. World J Surg Oncol, 10, 190. https://doi.org/10.1186/1477-7819-10-190
  20. Lee YT, Ng EK, Hung LC, et al (2005). Accuracy of endoscopic ultrasonography in diagnosing ascites and predicting peritoneal metastases in gastric cancer patients. Gut, 54, 1541-5. https://doi.org/10.1136/gut.2004.055772
  21. Liu J, Huang X-E, Tian G-Y, et al (2013). Phase II study on safety and efficacy of $Yadanzi^{(R)}$ (Javanica oil emulsion injection) combined with chemotherapy for patients with gastric cancer. Asian Pac J Cancer Prev, 14, 2009-12. https://doi.org/10.7314/APJCP.2013.14.3.2009
  22. Mandai K, Yasuda K (2012). Accuracy of endoscopic ultrasonography for determining the treatment method for early gastric cancer. Gastroenterol Res Pract, 2012, 245390.
  23. Massarrat S, Stolte M (2014). Development of gastric cancer and its prevention. Arch Iran Med, 17, 514-20.
  24. Mocellin S, Marchet A, Nitti D (2011). EUS for the staging of gastric cancer: a meta-analysis. Gastrointest Endosc, 73, 1122-34. https://doi.org/10.1016/j.gie.2011.01.030
  25. Mouri R, Yoshida S, Tanaka S, et al (2009). Usefulness of endoscopic ultrasonography in determining the depth of invasion and indication for endoscopic treatment of early gastric cancer. J Clin Gastroenterol, 43, 318-22. https://doi.org/10.1097/MCG.0b013e3181775966
  26. Opacic M, Rustemovic N (2003). Endoscopic ultrasonography and diagnostic algorithms in diseases of the gastrointestinal tract. Lijec Vjesn, 125, 192-9.
  27. Park JM, Ahn CW, Yi X, et al (2011). Efficacy of endoscopic ultrasonography for prediction of tumor depth in gastric cancer. J Gastric Cancer, 11, 109-15. https://doi.org/10.5230/jgc.2011.11.2.109
  28. Piazuelo MB, Correa P (2013). Gastric cancer: overview. Colomb Med (Cali), 44, 192-201.
  29. Puli SR, Reddy JB, Bechtold ML, et al (2008). Staging accuracy of esophageal cancer by endoscopic ultrasound: a metaanalysis and systematic review. World J Gastroenterol, 14, 1479-90. https://doi.org/10.3748/wjg.14.1479
  30. Tsuzuki T, Okada H, Kawahara Y, et al (2011). Usefulness and problems of endoscopic ultrasonography in prediction of the depth of tumor invasion in early gastric cancer. Acta Med Okayama, 65, 105-12.
  31. Viera AJ, Garrett JM (2005). Understanding interobserver agreement: the kappa statistic. Fam Med, 37, 360-3.
  32. Wang Z, Ma L, Zhang X-M, et al (2014). Risk of lymph node metastases from early gastric cancer in relation to depth of invasion: experience in a single institution. Asian Pac J Cancer Prev, 15, 5371. https://doi.org/10.7314/APJCP.2014.15.13.5371
  33. Yoshino J, Inui K, Kobayashi T, et al (2012). Diagnosis of the depth of gastric cancer invasion by endoscopic ultrasonography. Nihon Rinsho, 70, 1752-7.

Cited by

  1. Effects of premedication with Pronase for endoscopic ultrasound of the stomach: A randomized controlled trial vol.22, pp.48, 2016, https://doi.org/10.3748/wjg.v22.i48.10673
  2. Endoscopic ultrasound in gastric cancer staging before and after neoadjuvant chemotherapy. A comparison with PET-CT in a clinical series vol.5, pp.5, 2017, https://doi.org/10.1177/2050640616684697
  3. The role of endoscopic ultrasound on the preoperative T staging of gastric cancer vol.95, pp.36, 2016, https://doi.org/10.1097/MD.0000000000004580
  4. Validation of the prognostic impact of the new tumor-node-metastasis clinical staging in patients with gastric cancer pp.1436-3305, 2018, https://doi.org/10.1007/s10120-018-0799-9