Asian Pacific Journal of Cancer Prevention

Asian Pacific Journal of Cancer Prevention (아시아태평양암예방학회)
권호 표지
DOI QR코드

DOI QR Code

Dietary Fibre and the Risk of Colorectal Cancer: a Case-Control Study

  • Song, Y (Department of Public Health, Qingdao University) ;
  • Liu, M (Department of Public Health, Qingdao University) ;
  • Yang, FG (School of Nursing, Qingdao University Medical College, Qingdao University) ;
  • Cui, LH (Department of Public Health, Qingdao University) ;
  • Lu, XY (Basic Medical College, Qingdao University) ;
  • Chen, C (Department of Public Health, Qingdao University)
  • Published : 2015.05.18
Download PDF
⟨ Previous Next ⟩

Abstract

Background: Colorectal cancer is one of the most commonly occurring cancers in China. Dietary fibre has been thought to decrease the risk of colorectal cancer in Western countries. However, studies investigating the association between dietary fibre (particularly soluble and insoluble fibres) and colorectal cancer have hitherto been lacking in China. Objective: This case-control study examined the effect of dietary fibre intake on the risk of colorectal cancer, stratified by tumour site. Materials and Methods: The study included 265 cases (colon cancer, 105; rectal cancer, 144; colon and rectal cancer, 16) and 252 controls residing in Qingdao. A food frequency questionnaire that included 121 food items was used to collect dietary information. Odds ratio (OR) and 95% confidence intervals (CI) were calculated using unconditional logistic regression analysis. Results: For food groups, controls in the study consumed more vegetables, soy food and total fibre than did colorectal cancer patients (p<0.05). The intakes of fruit, meat and sea-food did not differ significantly between cases and controls. However, we did not find any association between soy food intake and colon cancer. We observed inverse associations between total fibre intake and colorectal, colon and rectal cancer (Q4 vs Q1: OR=0.44, 95%CI, 0.27-0.73; OR=0.40, 95%CI, 0.21-0.76; OR=0.52, 95%CI, 0.29-0.91). Vegetable fibre intake showed similar inverse associations (Q4 vs Q1: OR=0.51, 95%CI, 0.31-0.85; OR=0.48, 95%CI, 0.25-0.91; OR=0.53, 95%CI, 0.29-0.97). In addition, inverse associations were observed between soluble fibre and insoluble fibre and both colorectal cancer and colon cancer. No relationship was found between colorectal cancer and fruit, soy or grain fibre intakewhen the results were stratified by tumour site. Conclusions: The present study suggests that vegetable fibre and total fibre play very important roles in protecting against colorectal cancer. Soluble and insoluble fibres were inversely associated with only colorectal cancer and colon cancer.

Keywords

References

  1. Armstrong B, Doll R (1975). Environmental factors and cancer incidence and mortality in different countries, with special reference to dietary practices. Int J Cancer, 15, 617-31. https://doi.org/10.1002/ijc.2910150411
  2. Banque M, Raido B, Masuet C, et al (2012). Food groups and nutrient intake and risk of colorectal cancer: a hospital-based case-control study in Spain. Nutr Cancer, 64, 386-92. https://doi.org/10.1080/01635581.2012.657334
  3. Bennink MR (2001). Dietary soy reduces colon carcinogenesis in human and rats: soy and colon cancer. Adv Exp Med Biol, 492, 11-7.
  4. Bingham SA (1990). Mechanisms and experimental and epidemiological evidence relating dietary fiber (non-starch polysaccharides) and starch to protection against large bowel cancer. P Nutr Soc, 49, 153-71. https://doi.org/10.1079/PNS19900021
  5. Burkitt DP (1971). Epidemiology of cancer of the colon and rectum. Cancer, 28, 3-13. https://doi.org/10.1002/1097-0142(197107)28:1<3::AID-CNCR2820280104>3.0.CO;2-N
  6. Chen Q, Liu ZC, Cheng LP, et al (2012). Analysis of incidence and mortality of colorectal cancer in china, 2003-2007. Chin Cancer, 21, 179-82.
  7. Fechner A, Fenske K, Jahreis G (2013). Effects of legume kernel fibres and citrus fibre on putative risk for colorectal cancer: a randomized, double-blind, crossover human intervention trial. Nutr J, 12, 101. https://doi.org/10.1186/1475-2891-12-101
  8. Franceschi S, Favero A, La Vecchia C, et al (1997). Food groups and risk of colorectal cancer in Italy. Int J Cancer, 72, 56-61. https://doi.org/10.1002/(SICI)1097-0215(19970703)72:1<56::AID-IJC8>3.0.CO;2-3
  9. Fuchs CS, Giovannucci EL, Colditz GA, et al (1999). Dietary fiber and the risk of colorectal cancer and adenoma in woman. New Engl J Med, 340, 169-76. https://doi.org/10.1056/NEJM199901213400301
  10. Goncalves P, Martel F (2013). Butyrate and colorectal cancer: the role of butyrate transport. Curr Drug Metab, 14, 994-1008. https://doi.org/10.2174/1389200211314090006
  11. Hawk ET, Limburg PJ, Viner JL (2002). Epidemiology and prevention of colorectal cancer. Surg Clin North Am, 82, 905-41. https://doi.org/10.1016/S0039-6109(02)00046-4
  12. Jansen MCJF, Bueno-de-Mesquita HB, Buzina R, et al (1999). Dietary fiber and plant foods in relation to colorectal cancer mortality: the seven countries study. Int J Cancer, 81, 174-79. https://doi.org/10.1002/(SICI)1097-0215(19990412)81:2<174::AID-IJC2>3.0.CO;2-#
  13. Kato I, Akhmedkhanov A, Koenig K, et al (1997). Prospective study of diet and female colorectal cancer: the New York university women's health study. Nutr Cancer, 8, 276-81.
  14. Kojima M, Wakai K, Tamakoshi K, et al (2004). Diet and colorectal cancer mortality: results from the Japan collaborative cohort study. Nutr Cancer, 50, 23-32. https://doi.org/10.1207/s15327914nc5001_4
  15. Larsson S C, Rafter J, Holmberg L, Bergkvist L, Wolk A (2005). Red meat consumption and risk of cancers of the proximal colon, distal colon and rectum: the Swedish mammography cohort. Int J Cancer, 113, 829-34. https://doi.org/10.1002/ijc.20658
  16. Lin J, Zhang SM, Cook NR, et al (2005). Dietary intakes of fruit, vegetables, and fiber, and risk of colorectal cancer in a prospective cohort of women (United States). Cancer Causes Control, 16, 225-33. https://doi.org/10.1007/s10552-004-4025-1
  17. Li M, Zhang Z, Hill DL, et al (2005). Genistein, a dietary isoflavone, down-regulates the MDM2 oncogene at both transcriptional and posttranslational levels. Cancer Res, 65, 8200-8. https://doi.org/10.1158/0008-5472.CAN-05-1302
  18. Mai V, Flood A, Peters U, et al (2003). Dietary fibre and risk of colorectal cancer in the breast cancer detection demonstration project (BCDDP) follow-up cohort. Int J Epidemiol, 32, 234-9. https://doi.org/10.1093/ije/dyg052
  19. Ma J, Giovannucci E, Pollak M, et al (2004). A prospective study of plasma C-peptide and colorectal cancer risk in men. J Natl Cancer Inst, 96, 546-53. https://doi.org/10.1093/jnci/djh082
  20. Mason JB, Levesque T (1996). Folate: effects on carcinogenesis and the potential for cancer chemoprevention. Oncology, 10, 1727-36.
  21. McNeil NI, Rampton DS (1981). Is the rectum usually empty?-A quantitative study in subjects with and without diarrhea. Dia Colon Rectum, 24, 596-9. https://doi.org/10.1007/BF02605753
  22. Michels KB, Fuchs CS, Giovannucci E, et al (2005). Fiber intake and incidence of colorectal cancer among 76,947 women and 47,279 men. Cancer Epidemiol Biomarkers Prev, 14, 824-9.
  23. Michels KB, Giovannucci E, Joshipura KJ, et al (2000). Prospective study of fruit and vegetable consumption and incidence of colon and rectal cancers. J Natl Cancer Inst, 92, 1740-52. https://doi.org/10.1093/jnci/92.21.1740
  24. Negri E, Franceschi S, Parpinel M, et al (1998). Fiber intake and risk of colorectal cancer. Cancer Epidemiol Biomarkers Prev, 7, 667-71.
  25. Nomura AMY, Hankin JH, Henderson BE, et al (2007). Dietary fiber and colorectal cancer risk: the multiethnic cohort study. Cancer Cause Control, 18, 753-64. https://doi.org/10.1007/s10552-007-9018-4
  26. Norat T, Bingham S, Ferrari P, et al (2005). Meat, fish, and colorectal cancer risk: the European prospective investigation into cancer and nutrition. J Natl Cancer Inst, 97, 906-16. https://doi.org/10.1093/jnci/dji164
  27. Pietinen P, Malila N, Virtanen M, et al (1999). Diet and risk of colorectal cancer in a cohort of Finnish men. Cancer Causes Control, 10, 387-96. https://doi.org/10.1023/A:1008962219408
  28. Potter JD (1999). Colorectal cancer: molecules and populations. J Natl Cancer Inst, 91, 916-32. https://doi.org/10.1093/jnci/91.11.916
  29. Sandhu M S, White I R, McPherson K (2001). Systematic review of the prospective cohort studies on meat consumption and colorectal cancer risk a meta-analytical approach. Cancer Epidemiol Biomarkers Prev, 10, 439-46.
  30. Sato Y, Nakaya N, Kuriyama S, et al (2006). Meat consumption and risk of colorectal cancer in Japan: the miyagi cohort study. Eur J Cancer Prev, 15, 211-8. https://doi.org/10.1097/01.cej.0000197455.87356.05
  31. Sato Y, Tsubono Y, Nakaya N, et al (2005). Fruit and vegetable consumption and risk of colorectal cancer in Japan: the miyagi cohort study. Public Health Nutr, 8, 309-14.
  32. Schatzkin A (2000). Going against the grain? current status of the dietary fiber-colorectal cancer hypothesis. Biofactors, 12, 305-11. https://doi.org/10.1002/biof.5520120145
  33. Schatzkin A, Mouw T, Park Y, et al (2007). Dietary fiber and whole-grain consumption in relation to colorectal cancer in the NIN-AARP diet and health study. Am J Clin Nutr, 85, 1353-60
  34. Slattery ML, Curtin KP, Edwards SL, et al (2004). Plant foods, fiber, and rectal cancer. Am J Clin Nutr, 79, 274-81.
  35. Slavin JL, Martini MC, Jacobs DR, et al (1990). Plausible mechanisms for the protectiveness of whole grains. Am J Clin Nutr, 70, 459-63.
  36. Tabatabaei SM, Fritschi L, Knuiman MW, et al (2011). Meat consumption and cooking practices and the risk of colorectal cancer. Eur J Clin Nutr, 65, 668-75. https://doi.org/10.1038/ejcn.2011.17
  37. Terry P, G iovannucci E, Michels K B, et al (2001). Fruit, vegetables, dietary fiber, and risk of colorectal cancer. J Natl Cancer Inst, 93, 525-33. https://doi.org/10.1093/jnci/93.7.525
  38. Wakai K, Date C, Fukui M, et al (2007). Dietary fiber and risk of colorectal cancer in the Japan collaborative cohort study. Cancer Epidemiol Biomarkers Prev, 16, 668-75. https://doi.org/10.1158/1055-9965.EPI-06-0664
  39. Yang G, Shu X O, Li H, et al (2009). Prospective cohort study of soy food intake and colorectal cancer risk in women. Am J Clin Nutr, 89, 577-83. https://doi.org/10.3945/ajcn.2008.26742
  40. Yang Y, He M, Pan X (2004). China Food Composition Tables 2004. Peking Univ Med Press.
  41. Yin W, Huang C, Feng L (2004). Determination of total, soluble and insoluble dietary fiber in foods. J Hyg Res, 33, 331-3.
  42. Zhong X, Fang YJ, Pan ZZ, et al (2014). Dietary fiber and fiber fraction intakes and colorectal cancer risk in Chinese adults. Nutr Cancer, 66, 351-61. https://doi.org/10.1080/01635581.2013.877496

Cited by

  1. Dietary Ziziphus jujuba Fruit Influence on Aberrant Crypt Formation and Blood Cells in Colitis-Associated Colorectal Cancer Mice vol.16, pp.17, 2015, https://doi.org/10.7314/APJCP.2015.16.17.7561
  2. AMPK/p53 Axis Is Essential for α-Lipoic Acid–Regulated Metastasis in Human and Mouse Colon Cancer Cells vol.63, pp.7, 2015, https://doi.org/10.1097/JIM.0000000000000233
  3. BG-4, a novel anticancer peptide from bitter gourd (Momordica charantia), promotes apoptosis in human colon cancer cells vol.6, pp.1, 2016, https://doi.org/10.1038/srep33532
  4. Gut Fermentation of Dietary Fibres: Physico-Chemistry of Plant Cell Walls and Implications for Health vol.18, pp.10, 2017, https://doi.org/10.3390/ijms18102203
  5. Chinese consensus on the prevention of colorectal cancer (2016, Shanghai) vol.18, pp.2, 2017, https://doi.org/10.1111/1751-2980.12450
  6. Priority and prejudice: does low socioeconomic status bias waiting time for endoscopy? A blinded, randomized survey pp.1502-7708, 2017, https://doi.org/10.1080/00365521.2017.1402207
  7. ) to the Western-style diet attenuates the onset of metabolic disorders in rats pp.0034-6659, 2018, https://doi.org/10.1108/NFS-08-2018-0231
  8. Effects of Dietary Fibre from the Traditional Indonesian Food, Green Cincau (Premna oblongifolia Merr.) on Preneoplastic Lesions and Short Chain Fatty Acid Production in an Azoxymethane Rat Model of Colon Cancer vol.19, pp.9, 2018, https://doi.org/10.3390/ijms19092593