Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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A Case of Treatment of Idiopathic Immune-Mediated Polyarthritis in a Dog

개에서 발생한 특발성 면역매개성 다발성관절염의 치료 증례

  • Eom, Na-Young (Research Institute of Natural Science, College of Veterinary Medicine, Gyeongsang National University) ;
  • Lee, Hee-Chun (Research Institute of Natural Science, College of Veterinary Medicine, Gyeongsang National University) ;
  • Jang, Hyo-Mi (Research Institute of Natural Science, College of Veterinary Medicine, Gyeongsang National University) ;
  • Jung, Dong-In (Research Institute of Natural Science, College of Veterinary Medicine, Gyeongsang National University)
  • 엄나영 (경상대학교 수의과대학 기초과학연구소) ;
  • 이희천 (경상대학교 수의과대학 기초과학연구소) ;
  • 장효미 (경상대학교 수의과대학 기초과학연구소) ;
  • 정동인 (경상대학교 수의과대학 기초과학연구소)
  • Accepted : 2015.06.26
  • Published : 2015.08.31
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Abstract

A 12-year-old, castrated male, mixed-breed dog was referred to us with a history of depression, lameness, neck and multiple joints pain. Clinical signs had been deteriorating from rear limbs lameness leading to pain on all four limbs lameness for 7 days. Mild leukocytosis and increased C-reactive protein concentration were revealed in blood work. On radiography, degenerative change of humerus and cervical intervertebral space narrowing were found. The results of synovial fluid analysis revealed severe neutrophilic pleocytosis, decreased viscosity, increased turbidity and bacterial culture was negative. The antinuclear antibody test was negative and MRI results revealed mild cervical intervertebral disk disease (IVDD). Based on all tests, we diagnosed this case as idiopathic immune-mediated polyarthritis (IMPA). Prednisolone and mycophenolate mofetil were administered and clinical signs were resolved after 7 days. This case report demonstrated that clinical, diagnostic imaging and synovial fluid analysis findings and successful treatment result with prednisolone and mycophenolate mofetil in canine idiopathic IMPA.

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References

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