Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
권호 표지
DOI QR코드

DOI QR Code

Infectious Cholecystitis and Concurrent Endocarditis in a Dog: Rare but Important Association

개에서 감염성 담낭염과 동시 발병한 감염성 심내막염 1례

  • Jung, Joohyun (Ilsan animal medical center) ;
  • Choi, Mincheol (Veterinary Radiology Department, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University)
  • 정주현 (일산동물메디칼센타) ;
  • 최민철 (서울대 수의과대학 및 수의과학연구소)
  • Accepted : 2015.05.18
  • Published : 2015.08.31
Download PDF
⟨ Previous Next ⟩

Abstract

A 12-year-old castrated male miniature Schnauzer had anorexia, vomiting, lethargy, and fever for four days. The dog had leukocytosis, thrombocytopenia, hypoglycemia, hypoalbuminemia, hyperbilirubinemia, increased hepatic enzymes on hematologic and biochemical examinations. On abdominal ultrasonographs, there was an enlarged gallbladder with hyperechoic irregular wall thickening. Echocardiography showed vegetative change and regurgitation of aortic and mitral valves. E.coli was identified through ultrasound guided percutaneous cholecystocentesis and bile culture. Bacterial cholecystitis and concurrent endocarditis were diagnosed. The dog was recovered from sepsis with antibacterial and aggressive supportive therapy.

12살 중성화 수컷 Miniature Schnauzer 견이 4일 동안 식욕부진, 구토, 기면과 고열로 내원하였다. 혈액 및 혈청검사에서는 백혈구 증가증, 혈소판감소증, 저혈당증, 저알부민혈증, 고빌리루빈혈증, 간효소치의 증가를 보였다. 복부초음파 검사에서 담낭의 고에코성의 불규칙한 벽의 비후 소견이 두드러지고, 심초음파 검사에서 대동맥 및 승모판의 증식성 변화와 역류를 보였다. 초음파유도하에 경피적담낭첨자술을 통하여 담즙을 흡인하고 배양하여 E.coli 감염을 확인하였다. 따라서 세균성 담낭염과 병발한 심내막염을 진단하였다. 항생제 감수성 검사를 통한 적절한 항생 요법과 적극적인 입원 치료를 통하여 패혈증에서 회복이 되었다.

Keywords

References

  1. Aguirre, Ale. Diseases of the gallbladder and extrahepatic biliary system In: textbook of veterinary internal medicine. 7th ed. St. Louis, M issouri: Saunders Elsevier 2010; 1691-1692.
  2. Armstrong JA, Taylor SM, Tryon KA, Porter CD. emphysematous cholecystitis in a Siberian husky. Can Vet J 2000; 41: 60-62.
  3. Baddour LM, Wlison WR, Bayer AS, Fowler VG Jr, Bolger AF, Levison ME, Ferrieri P, Gerber MA, Tani LY, Gewitz MH, Tong DC, Steckelberg JM, Baltimore RS, Shulman ST, Burns JC, Falace DA, Newburger JW, Pallasch TJ, Takahashi M, Taubert KA. Infective endocarditis: diagnosis, antimicrobial therapy, and management complications. Circulation 2005; 111: 394-434. https://doi.org/10.1161/01.CIR.0000153812.64956.EF
  4. Boon JA. Acquired valvular disease. In: Veterinary echocardiography. 2nd ed. Wiley blackwelll, 2011; 267-318.
  5. Calvert C. Valvular bacterial endocarditis in the dog. J Am Vet Med Assoc 1982; 180: 1080-1084.
  6. Chomel BB, Wey AC, Kasten RW. Isolation of Bartonella washoensis from a dog with mitral valve endocarditis. J. Clin. Microbiol 2003; 41: 5327-5332. https://doi.org/10.1128/JCM.41.11.5327-5332.2003
  7. Goodman RA, Breitschwerdt EB. Clinicopathologic findings in dogs seroreactive to Bartonella henselae antigens. Am J Vet Res 2005; 66: 2060-2064. https://doi.org/10.2460/ajvr.2005.66.2060
  8. Henn JB, Gabreil MW, Kasten RW, Brown RN, Koehler JE, MacDonald KA, Kittleson MD, Thomas WP, Chomel BB. Infective endocarditis in a dog caused by Bartonella rochalimae and its phylogenic relationship with isolates from dogs, gray foxes and a human. J. Clin Microbiol 2009; 47: 787-790. https://doi.org/10.1128/JCM.01351-08
  9. Karchmer AW. Infective endocarditis In: A Textbook of Cardiovascular Medicine. 7th ed. Philadelphia: WB Saunders. 2005; 1077-1099.
  10. Ludwig LL, McLoughlin MA, Graves TK, Crisp MS. Surgical treatment of bile peritonitis in 24 dogs and 2 cats: a retrospective study (1987-1994). Vet Surg 1997; 26: 90-98. https://doi.org/10.1111/j.1532-950X.1997.tb01470.x
  11. Macdonald K. 2010. Infective endocarditis in dogs: diagnosis and therapy. Vet Clin North Am Small Anim Pract 2010; 40: 665-684. https://doi.org/10.1016/j.cvsm.2010.03.010
  12. Miller MW, Fox PR. Saunders AB. Pathologic and clinical features of infectious endocarditis. J Vet Cardiol 2004; 6: 35-43. https://doi.org/10.1016/S1760-2734(06)70056-X
  13. Muna WF, Ferrans VJ, Pierce JE, Roberts WC. Discrete subaortic stenosis in Newfoundland dogs: association of infective endocarditis. Am J Cardiol 1978; 41: 746-754. https://doi.org/10.1016/0002-9149(78)90827-5
  14. Neer MT. A review of disorders of the gallbladder and extrahepatic biliary tract in the dog and cat. J Vet Intern Med 1992; 6: 186-192. https://doi.org/10.1111/j.1939-1676.1992.tb00335.x
  15. Nyland TG, Mattoon JS, Herrgesell EJ, Wisner ER. Liver. In: Nyland TG, Mattoon JS, ed. Small animal diagnostic ultrasonography, 2nd ed. Philadelphia: Saunders 2002; 93-127.
  16. Ohad DG, Morick D, Avidor B, Harrus S. Molecular detection of Bartonella henselae and Bartonella koehlerae from aortic valves of Boxer dogs with infective endocarditis. Vet Microbiol 2010; 141: 182-185. https://doi.org/10.1016/j.vetmic.2009.08.005
  17. Olsen LH, Haggstrom J, Petersen HD. Acquired valvular heart disease In: textbook of veterinary internal medicine 7th ed. St. Louis, Missouri: Saunders, Elsevier. 2010; 1315-1319.
  18. Peddle G, Sleeper MM. Canine bacterial endocarditis: a review. J Am Anim Hosp Assoc 2007; 43: 258-263. https://doi.org/10.5326/0430258
  19. Perez C, Fujii Y, Fauls M. Hummel J, Breitschwerdt E. Fatal aortic endocarditis associated with community-acquired Serratia marcescens infection in a dog. J Am Anim Hosp Assoc 2011; 47: 133-137. https://doi.org/10.5326/JAAHA-MS-5616
  20. Rivers BJ, Walter PA, Johnston GR, Merkel LK, Hardy RM. Acalculous cholecystitis in four canine cases: ultrasonographic findings and use of ultrasonographic-guided, percutaneous cholecystocentesis in diagnosis. J Am Anim Hosp Assoc 1977; 33: 207-214.
  21. Sykes JE, Kittleson MD, Chomel BB, Byrne BA, MacDonald KA, Chomel BB. Clinicopathologic findings and outcome in dogs with infectious endocarditis: 71 cases (1992-2005). J Am Vet Med Assoc 2006; 228: 1735-1747. https://doi.org/10.2460/javma.228.11.1735
  22. Voros K, Nemeth T, Vrabely T, Manczur F, Toth J, Magdus M. Perge E. Ultrasonography and surgery of canine biliary diseases. Acta Vet Hung 2001; 49: 141-154. https://doi.org/10.1556/004.49.2001.2.3
  23. Voros K, Sterczer A, Manczur F, Gaal T. Percutaneous ultrasound-guided cholecystocentesis in dogs. Acta Vet Hung 2002; 50: 385-393. https://doi.org/10.1556/AVet.50.2002.4.2
  24. Wagner KA, Hartmann FA, Trepanier LA. Bacterial culture results from liver, gallbladder, or bile in 248 dogs and cats evaluated for hepatobiliary disease: 1998-2003. J Vet Intern Med 2007; 21: 417-424.
  25. Winter RL, Gordon SG, Zhang S, Hariu CD, Miller MW. Mural Endocarditis Caused by Corynebacterium mustelae in a Dog with a VSD. J Am Anim Hosp Assoc 2014; 50: 366-372. https://doi.org/10.5326/JAAHA-MS-6016