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Review of Association between Air Pollution and Heart Rate Variability (HRV)

대기오염과 심박변이도(Heart Rate Variability, HRV)의 연관성에 대한 고찰

  • Guak, Sooyoung (Department of Environmental Health Graduate School of Public Health, Seoul National University) ;
  • Lim, Chaeyun (Department of Environmental Health Graduate School of Public Health, Seoul National University) ;
  • Lee, Kiyoung (Department of Environmental Health Graduate School of Public Health, Seoul National University) ;
  • Park, Ji Young (Institute of Health and Environment, Seoul National University)
  • 곽수영 (서울대학교 보건대학원 환경보건학과) ;
  • 임채윤 (서울대학교 보건대학원 환경보건학과) ;
  • 이기영 (서울대학교 보건대학원 환경보건학과) ;
  • 박지영 (서울대학교 보건환경연구소)
  • Received : 2015.04.06
  • Accepted : 2015.07.14
  • Published : 2015.08.28

Abstract

Objectives: There is considerable evidence that polluted ambient air contributes to the risk of cardiovascular morbidity and mortality. Heart rate variability (HRV) is defined as the variation in heartbeat intervals and has been reported as a biological marker of cardiovascular disease. This article reviews the existing literature in order to examine the association between air pollution and HRV. Methods: Literature was searched using Web of Science with the key words of "air pollution", "heart rate variability" and other related terms. A total of 156 articles were listed. For review, 21 of those listed publications were chosen after excluding studies regarding chamber studies, occupational environment, secondhand smoke and automobile exhaust. Results: Research methods employed in the publications were classified by type of participants (elderly/adult), air pollution monitoring (ambient/personal) and HRV monitoring (continuous/spot). Among HRV parameters, power in the low frequency range (LF), power in the high frequency range (HF) and standard deviation of all NN intervals (SDNN) were all associated with air pollutants. The chosen studies were mostly based on elderly populations. In studies based on continuous HRV monitoring, LF and SDNN significantly decreased when $PM_{2.5}$ exposure increased. Conclusion: Continuous HRV monitoring combined with personal exposure monitoring has been one of the most common study methods in recent publications. We expect that this review will be useful for the study of the association between air pollution and cardiovascular effects using HRV.

Keywords

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