DOI QR코드

DOI QR Code

Eyelid Tumors: Clinical Data from an Eye Center in Ankara, Turkey

  • Gundogan, Fatih Cakir (Ophthalmology, Medical School, Gulhane Military Medical Academy) ;
  • Yolcu, Umit (Ophthalmology, Medical School, Gulhane Military Medical Academy) ;
  • Tas, Ahmet (Ophthalmology, Medical School, Gulhane Military Medical Academy) ;
  • Sahin, Omer Faruk (Department of Ophthalmology, Etimesgut Military Hospital) ;
  • Uzun, Salih (Department of Ophthalmology, Etimesgut Military Hospital) ;
  • Cermik, Hakan (Department of Pathology, Etimesgut Military Hospital, Pathology) ;
  • Ozaydin, Sukru (Department of Pathology, Etimesgut Military Hospital, Pathology) ;
  • Ilhan, Abdullah (Ophthalmology, Medical School, Gulhane Military Medical Academy) ;
  • Altun, Salih (Ophthalmology, Medical School, Gulhane Military Medical Academy) ;
  • Ozturk, Mustafa (Medical Oncology, GATA Medical School) ;
  • Sahin, Fahri (Hitit University, Education and Research Hospital) ;
  • Erdem, Uzeyir (Hitit University, Education and Research Hospital)
  • Published : 2015.06.03

Abstract

Introduction: The aim of the study was to explore the distribution of eyelid tumors in Ankara, the capital city of Turkey, from a histopathological point of view. Materials and Methods: Medical records of 1,502 patients who had eyelid surgery because of tumoral lesions were retrospectively reviewed after obtaining institutional review board approval. A total of 1,541 lesions with histopathologic diagnosis were included. Inflammatory tumoral lesions were excluded. The lesions were categorized into three groups according to the origin: epidermal, adnexal tumors and 'others', including melanocytic, neural and vascular lesions. Results: Of the total of 1,541, 908 lesions were epidermal in origin. Only 22 (1.5%) were malignant, and 6.0% was premalignant lesions such as actinic keratosis and Bowen's disease. Twenty-one of 22 malignant lesions were basal cell carcinoma. There was only one patient with squamous cell carcinoma and no sebaceous cell carcinoma. Among the benign tumors (92.5%), squamous papilloma was the most frequent (21.8% of all lesions). The other frequent lesions were nevus (17.6%), seborrheic keratosis (17.3%), hydrocystomas (10.6%), xanthelasma (7.6%) and epidermal cysts (7.2%). Conclusions: The results of this study are in accordance with published literature. The absence of sebaceous cell carcinomas needs to be stressed.

Keywords

References

  1. Abdi U, Tyagi N, Maheshwari V, et al (1996). Tumours of eyelid: a clinicopathologic study. J Indian Med Assoc, 94, 405-9.
  2. Allali J, D’Hermies F, Renard G (2005). Basal cell carcinomas of the eyelids. Ophthalmologica, 219, 57-71. https://doi.org/10.1159/000083263
  3. Bagheri A, Tavakoli M, Kanaani A, et al (2013). Eyelid masses: a 10-year survey from a tertiary eye hospital in Tehran. Middle East Afr J Ophthalmol, 20, 187-92. https://doi.org/10.4103/0974-9233.114788
  4. Bhurgri Y, Bhurgri H, Usman A, et al (2003). Epidemiology of ocular malignancies in Karachi. Asian Pac J Cancer Prev, 4, 352-7.
  5. Bianciotto C, Demirci H, Shields CL, et al (2009). Metastatic tumors to the eyelid: report of 20 cases and review of the literature. Arch Ophthalmol, 127, 999-1005. https://doi.org/10.1001/archophthalmol.2009.120
  6. Chang CH, Chang SM, Lai YH, et al (2003). Eyelid tumors in southern Taiwan: a 5-year survey from a medical university. Kaohsiung J Med Sci, 19, 549-54. https://doi.org/10.1016/S1607-551X(09)70505-4
  7. Coroi MC, Rosca E, Mutiu G, et al (2010). Eyelid tumors: histopathological and clinical study performed in County Hospital of Oradea between 2000-2007. Rom J Morphol Embryol, 51, 111-5.
  8. Deprez M, Uffer S (2009). Clinicopathological features of eyelid skin tumors. A retrospective study of 5504 cases and review of literature. Am J Dermatopathol, 31, 256-62.
  9. Frost CA, Green AC, Williams GM (1998). The prevalence and determinants of solar keratoses at a subtropical latitude (Queensland, Australia). Br J Dermatol, 139, 1033-9. https://doi.org/10.1046/j.1365-2133.1998.02560.x
  10. Gajda M, Kaminska-Winciorek G (2014). Do not let to be late: overview of reasons for melanoma delayed diagnosis. Asian Pac J Cancer Prev, 15, 3873-7. https://doi.org/10.7314/APJCP.2014.15.9.3873
  11. Hilovsky JP (1995). Lid lesions suspected of malignancy. J Am Optom Assoc, 66, 510-5.
  12. Lai TF, Huilgol SC, Selva D, et al (2004). Eyelid sebaceous carcinoma masquerading as in situ squamous cell carcinoma. Dermatol Surg, 30, 222-5.
  13. Leffell DJ (2000). The scientific basis of skin cancer. J Am Acad Dermatol, 42, 18-22. https://doi.org/10.1067/mjd.2000.103340
  14. Lin HY, Cheng CY, Hsu WM, et al (2006). Incidence of eyelid cancers in Taiwan: a 21-year review. Ophthalmology, 113, 2101-7. https://doi.org/10.1016/j.ophtha.2006.06.001
  15. Mannor GE, Chern PL, Barnette D (2009). Eyelid and periorbital skin basal cell carcinoma: oculoplastic management and surgery. Int Ophthalmol Clin, 49, 1-16.
  16. Margo CE, Waltz K (1993). Basal cell carcinoma of the eyelid and periocular skin. Surv Ophthalmol, 38, 169-92. https://doi.org/10.1016/0039-6257(93)90100-L
  17. Ni Z (1996). [Histopathological classification of 3,510 cases with eyelid tumor]. Zhonghua Yan Ke Za Zhi, 32, 435-7.
  18. Piest KL (1992). Malignant lesions of the eyelids. J Dermatol Surg Oncol, 18, 1056-9. https://doi.org/10.1111/j.1524-4725.1992.tb02783.x
  19. Salasche SJ (2000). Epidemiology of actinic keratoses and squamous cell carcinoma. J Am Acad Dermatol, 42, 4-7. https://doi.org/10.1067/mjd.2000.103342
  20. Salomon J, Bieniek A, Baran E, et al (2004). Basal cell carcinoma on the eyelids: own experience. Dermatol Surg, 30, 257-63.
  21. Takamura H, Yamashita H (2005). Clinicopathological analysis of malignant eyelid tumor cases at Yamagata university hospital: statistical comparison of tumor incidence in Japan and in other countries. Jpn J Ophthalmol, 49, 349-54. https://doi.org/10.1007/s10384-005-0229-5
  22. Turgay AS, Sari D, Can M, et al (2005). Determination of sunburn and skin cancer risk of outpatients in a dermatology polyclinic. Asian Pac J Cancer Prev, 6, 143-6.
  23. Xu XL, Li B, Sun XL, et al (2008). Clinical and pathological analysis of 2639 cases of eyelid tumors. Zhonghua Yan Ke Za Zhi, 44, 38-41 (in Chinese).