Asian Pacific Journal of Cancer Prevention

  • 제16권10호
  • /
  • Pages.4257-4260
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  • 2015
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  • 1513-7368(pISSN)
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  • 2476-762X(eISSN)
아시아태평양암예방학회 (Asian Pacific Journal of Cancer Prevention)
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Lympho-Vascular Space Invasion Indicates Advanced Disease for Uterine Papillary Serous Tumors Arising from Polyps

  • Ilker, Selcuk (Gynecologic Oncology Unit, Zekai Tahir Burak Women's Health, Education and Research Hospital) ;
  • Elmas, Korkmaz (Gynecologic Oncology Unit, Zekai Tahir Burak Women's Health, Education and Research Hospital) ;
  • Emre, Ozgu (Gynecologic Oncology Unit, Zekai Tahir Burak Women's Health, Education and Research Hospital) ;
  • Mengu, Turker (Pathology Unit, Zekai Tahir Burak Women's Health, Education and Research Hospital) ;
  • Erkaya, Salim (Obstetrics and Gynecology, Hitit University, Faculty of Medicine, Corum, Turkey and Gynecologic Oncology Unit, Zekai Tahir Burak Women's Health, Education and Research Hospital) ;
  • Tayfun, Gungor (Department of Obstetrics and Gynecology, Hitit University, Faculty of Medicine, Corum, Turkey and Gynecologic Oncology Unit, Zekai Tahir Burak Women's Health, Education and Research Hospital)
  • 발행 : 2015.06.03
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초록

Background: Uterine papillary serous tumors are rarely seen and behave aggressively. Our aim was to evaluate uterine papillary serous tumors arising from polyps. Materials and Methods: Clinicopathological data of patients with uterine serous cancer arising from a polyp at the Gynecological Oncology Department of Zekai Tahir Burak Women's Health Education and Research Hospital were reviewed retrospectively. Results: We analyzed patients according to FIGO 2009 staging system as stage 1A and higher than stage 1A (3 and 6, respectively). All the patients were postmenopausal. Mean CA-125, CA-19.9 and CA15.3 levels were elevated in higher than stage 1A group. However we did not find a statistical difference between age, parity, polyp size, CA-125, CA-15.3, CA-19.9 and CEA levels. Lympho-vascular space invasion (LVSI) showed predictivity for advanced disease (p=0.025). Conclusions: The histopathologic nature of uterine serous carcinoma is a unique entity. LVSI is a prognosticator for defining an advanced stage uterine papillary tumor.

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참고문헌

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피인용 문헌

  1. Adjuvant Pelvic Radiation “Sandwiched” Between Paclitaxel/Carboplatin Chemotherapy in Women With Completely Resected Uterine Serous Carcinoma pp.1048-891X, 2018, https://doi.org/10.1097/IGC.0000000000001359
  2. Malignant Endometrial Polyps in Uterine Serous Carcinoma: The Prognostic Value of Polyp Size and Lymphovascular Invasion vol.28, pp.3, 2018, https://doi.org/10.1097/IGC.0000000000001213