Asian Pacific Journal of Cancer Prevention

  • 제16권10호
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  • Pages.4247-4250
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  • 2015
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  • 1513-7368(pISSN)
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  • 2476-762X(eISSN)
아시아태평양암예방학회 (Asian Pacific Journal of Cancer Prevention)
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Predicting Lympho-Vascular Space Invasion in Endometrial Cancers with Mucinous Carcinomatous Components

  • Ilker, Selcuk (Gynecologic Oncology Unit, Zekai Tahir Burak Women's Health, Education and Research Hospital) ;
  • Nilufer, Cetinkaya (Gynecologic Oncology Unit, Zekai Tahir Burak Women's Health, Education and Research Hospital) ;
  • Firat, Cuylan Zeliha (Gynecologic Oncology Unit, Zekai Tahir Burak Women's Health, Education and Research Hospital) ;
  • Bulent, Ozdal (Gynecologic Oncology Unit, Zekai Tahir Burak Women's Health, Education and Research Hospital) ;
  • Hatice, Bayramoglu (Pathology Unit, Zekai Tahir Burak Women's Health, Education and Research Hospital) ;
  • Tayfun, Gungor (Department of Obstetrics and Gynecology, Hitit University, Faculty of Medicine)
  • 발행 : 2015.06.03
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초록

Objective: To determine the predictors of lympho-vascular space invasion (LVSI) in endometrial cancers which contain mucinous carcinomatous histology. Materials and Methods: Clinical and histopathological data of endometrial carcinomas with a mucinous carcinomatous component diagnosed between January 2007 and January 2014 at the Gynecologic Oncology Department of Zekai Tahir Burak Women's Health Education and Research Hospital were reviewed retrospectively. Results: Twelve patients (25.5%) were positive for LVSI and 35 (74.5%) patients were negative. Patients with LVSI were mostly staged higher than 1A. Mean age, BMI and parity were not significantly different between patient groups. Larger tumor diameter (${\geq}2cm$) (p=0.04) and elevated Ca125 and Ca-19.9 (p=0.01) levels were significant for predicting LVSI. We also found>1/2 myometrial invasion (p<0.001), cervical stromal involvement (p=0.002) and higher grade (2-3) (p=0.001) significant for predicting LVSI. In multivariate analysis we found only grade significant for predicting LVSI. Conclusions: Especially grade of tumor is a crucial factor for determining LVSI in endometrial cancers with mucinous carcinomatous components.

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참고문헌

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피인용 문헌

  1. Accuracy of Sentinel Node in Detecting Lymph Node Metastasis in Primary Endometrial Carcinoma vol.16, pp.15, 2015, https://doi.org/10.7314/APJCP.2015.16.15.6691