The Journal of Pediatrics of Korean Medicine (대한한방소아과학회지)

The Association of Korean Oriental Pediatrics (대한한방소아과학회)
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The Review of the Herbal Medicines with Phytoestrogenic Effect

식물성에스트로겐 작용이 보고된 한약재에 관한 고찰

  • Lee, Sun Haeng (Department of Pediatrics of Korean Medicine, Kyung Hee University Hospital at Gangdong / Pediatrics of Clinical Korean Medicine, Graduate School, Kyung Hee University) ;
  • Kim, Hyung Joong (Department of Pediatrics of Korean Medicine, Kyung Hee University Hospital at Gangdong / Pediatrics of Clinical Korean Medicine, Graduate School, Kyung Hee University) ;
  • Lee, Eun Ju (Department of Pediatrics of Korean Medicine, Kyung Hee University Hospital at Gangdong / Pediatrics of Clinical Korean Medicine, Graduate School, Kyung Hee University) ;
  • Chang, Gyu Tae (Department of Pediatrics of Korean Medicine, Kyung Hee University Hospital at Gangdong / Pediatrics of Clinical Korean Medicine, Graduate School, Kyung Hee University)
  • 이선행 (강동경희대학교병원 한방소아과, 경희대학교 대학원 임상한의학과 소아과학교실) ;
  • 김형중 (강동경희대학교병원 한방소아과, 경희대학교 대학원 임상한의학과 소아과학교실) ;
  • 이은주 (강동경희대학교병원 한방소아과, 경희대학교 대학원 임상한의학과 소아과학교실) ;
  • 장규태 (강동경희대학교병원 한방소아과, 경희대학교 대학원 임상한의학과 소아과학교실)
  • Received : 2015.05.03
  • Accepted : 2015.05.15
  • Published : 2015.05.31
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Abstract

Objectives Medical plant has a big role in Herbal Medicines, and most medical plant has phytoestrogens. Therefore some estrogenic effects have been reported in a lot of Korean Medicine literature. Phytoestrogens should be used carefully in children. The objective of this study is to identify reported phytoestrogenic effects in Herbal Medicines and to evaluate the characteristics of the phytoestrogens in Herbal Medicines. Methods A literature search was done with using 8 databases with a limit of reports until 12/31/2013. The estrogenic effects were summarized by each individual Korean Medicine. The frequency of the phytoestrogens was also investigated depending on the Korean medical categorization by the treatment effect. Results and Conclusions Phytoestrogenic effects were reported in 89 Herbal Medicines. Phytoestrogens were act bidirectionally, and the effect was fairly weak compared to estrogen. Phytoestrogenic effect was variable on different cells and tissues. The most frequent phytoestrogenic effect was in tonifying and replenishing medicinal, the following orders were heat-clearing, exterior-releasing, and blood-activating and stasis-dispelling medicinal. Phytoestrogens were not reported in dampness-resolving, digestant, orifice-opening, emetic medicinal.

Keywords

References

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